1Y3I


Conserved Protein Domain Family
NAD_kinase
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pfam01513: NAD_kinase 
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ATP-NAD kinase N-terminal domain
Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.
Links
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Statistics
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PSSM-Id: 426300
Aligned: 17 rows
Threshold Bit Score: 90.1153
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1Y3I_B   7 VLLVVHTG-------------RDEATETARRVEKVLGDNk-----iALRVLSAEAVDRGSLHlapddm------------ 56  Mycobacterium tubercu...
Q8U1V2   3 FGIVARRD-------------KEEALKLAYRVYDFLKVS-------GYDVVVDKDTYEHFPY------------------ 44  Pyrococcus furiosus D...
O26958   4 IGIIARFD-------------VAEAVEIAERVASFLLNR-------GVEITVDLKLTEELP------------------- 44  Methanothermobacter t...
Q58327 304 FGIVVRED-------------KEEAINLAIEICKYLKDK-------NIPFCVEDFL------------------------ 339 Methanocaldococcus ja...
P27748  15 VGIIANPIsardirrviananSLQLADRVNIVLRLLAALascgverVLMMPDREGLRVMLARhlarrqgpdsglpa---- 90  Cupriavidus necator H16
P44497  11 IALVGKPR-------------NDINLQMHKNLFHWLMER-------GYQVLVEKEVAITLELp----------------- 53  Haemophilus influenza...
P0A7B3   8 IGIVGHPR-------------HPTALTTHEMLYRWLCTK-------GYEVIVEQQIAHELQLk----------------- 50  Escherichia coli K-12
O13863 165 VLLICNDN--------------KESIERSVELAQWLLDTfsf-tpsSSHNNMASSNTQSNTQlsemeseeksfnkdvypn 229 Schizosaccharomyces p...
P32622 109 LIIICNIN-------------DISTVFLMREVVEWILRNf-----hSITVYVQDIFKKSTQFavgdlckds--------- 161 Saccharomyces cerevis...
P73955   6 VIIAHKAG-------------HNESKTYAERCARELEAR-------GCKVLMGPSGIKD--------------------- 44  Synechocystis sp. PCC...

1Y3I_B  57 ------------------------------ramgveIEVVDADQHAADGCELVLVLGGDGTFLRAAELARNaSIPVLGVN 106 Mycobacterium tubercu...
Q8U1V2  45 ------------------------------------FNERDVIPLEEFDVDFIIAIGGDGTILRIEHMTKK-DIPILSVN 87  Pyrococcus furiosus D...
O26958  45 ------------------------------------QLREYGEDIRNMDADMILTIGGDGTILRTRSLIEDkEIPILGIN 88  Methanothermobacter t...
Q58327 340 ------------------------------------RERVGGDKFDISAISHIIAIGGDGTILRASRLVNGeTIPIIAVN 383 Methanocaldococcus ja...
P27748  91 -----------------------vdyldmpvtarvdDTLRAARCMADAGVAAIIVLGGDGTHRAVVRECG--AVPIAGLS 145 Cupriavidus necator H16
P44497  54 ------------------------------------FEHLATLEEIGHRAQLAIVIGGDGNMLGRARVLAKyDIPLIGIN 97  Haemophilus influenza...
P0A7B3  51 ------------------------------------NVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARyDIKVIGIN 94  Escherichia coli K-12
O13863 230 deytpftpknqfviyledtlasldvveslspkknvrFWTSELCTQCPNLFDCVITVGDDSAALRASWLFQDvVPPVLSFS 309 Schizosaccharomyces p...
P32622 162 ----------------------------ncsknrvkYWSKEFVKKHDSFFDLMITLGGDGTVLFASSIFTKdVPPIVPFA 213 Saccharomyces cerevis...
P73955  45 ------------------------------------NPYPVFLASATEKIDLALVLGGDGTTLAAARHLSPeGIPILSVN 88  Synechocystis sp. PCC...

1Y3I_B 107 L-GRIGFLAEA--EAEAIDAVLEHVVA 130 Mycobacterium tuberculosis
Q8U1V2  88 M-GTLGFLTEV--EPSDTFFALSRLIE 111 Pyrococcus furiosus DSM 3638
O26958  89 M-GTVGFLTEV--DPENVFSALEAVLR 112 Methanothermobacter thermautotrophicus str. Delta H
Q58327 384 M-GKVGFLAEF--CKDEVFEIIDKVIY 407 Methanocaldococcus jannaschii DSM 2661
P27748 146 T-GTNNAYPEM--REPTIIGLATGLYA 169 Cupriavidus necator H16
P44497  98 R-GNLGFLTDI--DPKNAYSQLEACLE 121 Haemophilus influenzae Rd KW20
P0A7B3  95 R-GNLGFLTDL--DPDNAQQQLADVLE 118 Escherichia coli K-12
O13863 310 T-AKAGFLSIL--PIAEYTKTLDLIFH 333 Schizosaccharomyces pombe 972h-
P32622 214 L-GSLGFLTNF--EFQNFKETLKHILT 237 Saccharomyces cerevisiae S288C
P73955  89 VgGHLGFLTEPfdVFQDTQKVWDRLNQ 115 Synechocystis sp. PCC 6803 substr. Kazusa
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