2MAH


Conserved Protein Domain Family
Fz

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pfam01392: Fz 
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Fz domain
Also known as the CRD (cysteine rich domain), the C6 box in MuSK receptor. This domain of unknown function has been independently identified by several groups. The domain contains 10 conserved cysteines.
Statistics
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PSSM-Id: 426238
Aligned: 279 rows
Threshold Bit Score: 32.9163
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2MAH_A        16 CYPTsnATNTCFGsklpYELSSLd-----lTDFHtekELndK-----LNDYYA-LKHVpkCWAAIQPFLCAVFKPKCEk- 83  fruit fly
XP_009422599 466 CEPV--QVEMCLGl--sYNTTAFpn---iwVGMTtqeEVaeV-----LSGYKSlTSLP--CYQHFRRLLCGLLVPRCTpl 531 chimpanzee
XP_027691332  94 CEPI--QVEMCQGl--sYNTTAFpn---tlMTLDsqqEVeeM-----LKGYKTlTDLP--CYQPFRRLLCGLLLPHCTps 159 common wombat
XP_005988168 349 CEPV--EVEMCQGl--sYNETSFpn---iwLQVPdqqSAmkI-----LKDYKIlMELF--CYQHLRLLICSLFIPKCSae 414 coelacanth
KFO61645      49 CEPV--EVEMCLGl--gYNATSFpn---iwLAIPdqeGAaeV-----LQDYQTlMELA--CYQHLRLLICSLFVPKCTpd 114 American crow
XP_016853844 360 CEPI--EVEMCLGl--sYNTTSFpn---iwLAIPdqqGAeeI-----LQDYMMlKDLA--CYPHLRLFICSLFVPKCTpd 425 green anole
XP_015193108 468 CEPI--KVEMCQGl--sYNLTSFpn---iwLSISdqrEAanA-----LKHYKVlTELA--CFPALRRLVCAVFVPRCSae 533 spotted gar
CAG06452     358 CETI--EVEMCRGl--sYNLTSFpn---iwLSIAdqrEAaaL-----LQQYRVlMDLA--CFQPLRRLVCGMFLPQCSpq 423 spotted green p...
XP_009289590 459 CELI--QVEMCRDl--sYNLTSFpn---iwLSLSdqrEAasI-----LHKYRVlVDLP--CFESFRQLVCGMFLPRCSpq 524 zebrafish
XP_020563475 240 E-----VCQTVLQ----DNFLVFfnaslsdPEDM---QE--YlvqswWTELEGlSTLCspALLSLLCHSSFPNCNPSGl- 304 Japanese medaka
2MAH_A        84 INGedMVyLPSYEMCRI-TMEPCRILYntT------------------FFPKflrCNEtlFPTK 128 fruit fly
XP_009422599 532 G----SVlPPCRSVCQE-AEHQCQSGL--All--------------gtPWPFn--CNR--LPEA 570 chimpanzee
XP_027691332 160 G----GIlPPCRPVCLD-AEHHCQPDL--Epl--------------giSWSFn--CKS--LPDA 198 common wombat
XP_005988168 415 G----GVlQPCRSVCLS-AENQCQHSL--Sll--------------giLWPFn--CNM--LPDS 453 coelacanth
KFO61645     115 G----GVlQPCRAVCLA-AELRCQQSL--Gll--------------giLWPIn--CNI--LPDS 153 American crow
XP_016853844 426 G----GIlQPCRSICLG-TEQRCQQSL--Sfl--------------gvPWPLn--CNV--LPDS 464 green anole
XP_015193108 534 G----GVlQPCRSVCVS-AEQQCRPAL--Eql--------------avSWPFn--CHL--FPDS 572 spotted gar
CAG06452     424 G----GVlQPCRSVCSS-AEQQCSQAL--Dlf--------------sfSWPFn--CHL--LPDL 462 spotted green pufferfish
XP_009289590 525 S----GVlQLCQSVCST-AELQCSPAL--Slf--------------slNWPFn--CLL--LPDS 563 zebrafish
XP_020563475 305 GPApkPVcREHCLAVKElYCYKEWLLLegSrsvqpelfdsvlgshylpKCQA---LPS--LHAD 363 Japanese medaka
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