Conserved Protein Domain Family
PPDK_N

?
pfam01326: PPDK_N 
Pyruvate phosphate dikinase, AMP/ATP-binding domain
This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Statistics
?
PSSM-Id: 426201
Aligned: 103 rows
Threshold Bit Score: 170.465
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_015751141         42 ELLVGGKNYNT---------AII---SElED-----VRAPQFRAISAKAFHKHLDESKvnatlVRSIVNQEYDQTDwSDh 104  Desulfo...
Q117L5               15 WNIVGEKAFYL---------ADL----MdKG-----YPISPGFVIPANTLWQFLERINwsdplLANFPDSSLN-FNiDD- 74   Trichod...
jgi:SpiGrapes_1862  446 SGSLGGKGRGLafidmelrsSGIldkYPnIY-----LSIPRTVVVTTDQFSQFLEDNA-----LTDIISSEMPD------ 509 
CDE58667            432 DGSLGGKGRGLaf------iGAMikrYPkLEqenfaVNIPKTVVICTDIFDEFMETNElypiaLSDTDND---------- 495 
Q2LQG3              331 tgYIGGKAVGMmi------aRNMllqDRsFDwh-ncLEPHDSFFIGSDVFYTYIVENGwwklrMDQKTREGYFE------ 397  Syntrop...
WP_012175281        292 tgfIGGKSVGMll------aRNIlarEEgFDwq-gvLEHHDSFYIGSDVFYSFIVQNGwwqtfMAHKTGEGYFD------ 358  Desulfo...
WP_013561090        196 tgRIGGKAAGMll------aLRIlrsSGdPEil-ecLNVPDSYFIGSDVFYTFMTVNN-----LVRWNDQKYKS------ 257  Anaerol...
Q2LW96              346 rgtIGGKGTGMfl------aGKIlkrESeETplfnaIKVPKTWYITTDEMREFLHYNN-----LLGLNEQRYRD------ 408  Syntrop...
WP_014857458        348 hgkLGGKSAGLfv------aSHIlrkEAsNNdllknIKVPNTWYITSDGILNFMQHNN-----LEEVLEQKYKE------ 410  Meliori...
EHO41966            347 ygkLGGKSAGMfl------aYRIlktVEdPQnlfenIRTPKTWYITSDTMIYFMHYNN-----LDELLEQKYKP------ 409 
WP_015751141        105 einkdpdflkkfvrnvaekvreaqskpagssliqlrkfinnvvegfatspegIDQLRKRSILVQVAILSVKLPDEVHAAV 184  Desulfo...
Q117L5               75 ----------------------------------------------------YQQWQHISQSINYYIFSADLPLELVSSL 102  Trichod...
jgi:SpiGrapes_1862  510 ------------------------------------------------------------NNLLKIFLSKPLSSELVLNL 529 
CDE58667            496 -------------------------------------------------------------TILKYFLRASLPSRLIEDL 514 
Q2LQG3              398 ----------------------------------------------------------VAKVLREKMLDGRFPEEIEEQF 419  Syntrop...
WP_012175281        359 ----------------------------------------------------------RAKELKEKIPHGSFPDEIVERL 380  Desulfo...
WP_013561090        258 ----------------------------------------------------EEEMRTDYPQIVRDFESGQFPVDILDHL 285  Anaerol...
Q2LW96              409 ----------------------------------------------------LYEIRIDYPNVIQMMKNSNFPASIIKSL 436  Syntrop...
WP_014857458        411 ----------------------------------------------------IEEVRIEYPHIVQLFKNSEFPPDIVKGL 438  Meliori...
EHO41966            410 ----------------------------------------------------VNEVRKEYPQVVQLFKSSHFPPEIVKGV 437 
WP_015751141        185 AQAYRDICKeaglenVPVAVRSSAAGEDS--------RKKAFAGLQDTYL--NIVDAEHCVE----AYHWDCASAYNLRS 250  Desulfo...
Q117L5              103 ESAINNL-----------------NAESLifqpylasPKLETFGILDVKI--CQAKSEKFTQ----VIKQAWSEIFKAKS 159  Trichod...
jgi:SpiGrapes_1862  530 SEIIQVIR-------QPISVRSSSLLEDS--------HFQPFAGVYETCMipNCGNDKQRLDelcdAIRCVWASTFFRRA 594 
CDE58667            515 MAFSEVVK-------GPIAIRSSSLLEDS--------HYQPFAGIYSTYMipKQEDKYEMLRslsdAIKAVYASVFYQDS 579 
Q2LQG3              420 WRVIEYFGQ------SPIIVRSSSLLEDA--------FGNAFAGKYESIFcvNQGTPEERYRqfreAIRRVYASTLNEDA 485  Syntrop...
WP_012175281        381 TLMLEYFGQ------SPIIVRSSSLLEDA--------FGSAFAGKYDSFFcvNQGSPEKRYRefegAMLRVFESTMGEDA 446  Desulfo...
WP_013561090        286 RDLLARIGK------KPLIVRSSSLLEDN--------FGTSFAGKYESVFlpNQGDVEQNLRelvrGITRVYASTLNPGA 351  Anaerol...
Q2LW96              437 AMALDDFGD------SPLIVRSSSLLEDQ--------SGAAFSGKYKSLFlaNQGTKKDRLEdltnAIIEVYASIYSPDS 502  Syntrop...
WP_014857458        439 SVALDDFGD------VPLVVRSSSLLEDQ--------MDASFSGKYKSLFlaNQGSKAERLAalmdAIAEVYASTFSPDP 504  Meliori...
EHO41966            438 AMALDDFGE------KPLIVRSSSLLEDR--------LGSAFSGKYKSLFiaNQGSKAERLEalldAIAEVYASTIGPDP 503 
WP_015751141        251 MTYRREAILDAvnqaertgddsiatqakeewaiENTSLSVCIMRMINPV--------ISGTAFSAD---------TATGc 313  Desulfo...
Q117L5              160 LLYWHIHQVDI----------------------QKLQPVILVQSLQSAI--------ASGTMQAf--------------- 194  Trichod...
jgi:SpiGrapes_1862  595 KEYLKATDHMM----------------------EDEKMAVVIQQVIGSEhgsywypnISGVARSLNyypi-ggekPEDG- 650 
CDE58667            580 KAYMTATSNLI----------------------DQEKMAIVLQEVVGTQygdhyyptISGVARSLNfypi-gnekAEDG- 635 
Q2LQG3              486 LAYRLQRGLEK----------------------HDEQMALLVQRVSGSYrkdcffpdLAGVGLSYNtfvwkkemdPRAG- 542  Syntrop...
WP_012175281        447 LAYRRQRGLDR----------------------SDEQMALLVQRVSGAYhksyffpeLAGVGLSRNpfvwkkgmdPGAG- 503  Desulfo...
WP_013561090        352 LLYRRSKRLQD----------------------YDERMAILLQVVEGERygryfmphAAGVAFSRNlyrwapqirREDG- 408  Anaerol...
Q2LW96              503 VQYRAERGLLD----------------------YPEEMGIMIQEVVGKRigpyyfplYGGVAFSNNefrwsprikRSDG- 559  Syntrop...
WP_014857458        505 IEYRAERGLLD----------------------FHEEMGIMIQEVIGKRvgdyfipaYAGVAFSVNefrwsprikREDG- 561  Meliori...
EHO41966            504 IEYRAERGLLD----------------------FHEEMGVMIQEVVGKQvgdyffpaFAGVAFSNNefrwsprirREDG- 560 
WP_015751141        314 rgtdrNDLVSMDASYGLGEAVVGG----MVTPDKFYVFQRDGAsevVVRYMGCKDKKIIYDEdkgGTKLVE--------- 380  Desulfo...
Q117L5              195 -----ANSWEIQATYGLGISIELG----QVIPDSFLISPKNYTi--QEKKLGNKIIAYNLDTamtKVSYINtwqeidntq 263  Trichod...
jgi:SpiGrapes_1862  651 ---------VGMLSFGFGKSVVDNgsvfRFSPTHPKRPVQf-----LGGTQSSAQNNFYALNlntG-------------- 702 
CDE58667            636 ---------IANIALGLGKYIVDGgltlRFSPRHPHNILQMSS---TDFALRETQTRFYALD------------------ 685 
Q2LQG3              543 ---------MLRLVLGLGTRAVN-----RVENDYPRIVPLDVPl--LRPHSGENDLRRYSQHdvdV-------------- 592  Syntrop...
WP_012175281        504 ---------MARLVFGLGTRAVN-----RVENDYPRIVAMDDPl--VKPLAGTEDIRRFSQRfvdL-------------- 553  Desulfo...
WP_013561090        409 ---------FVRLVWGLGTRAVD-----RVGNDYPRLVALSHPl--LRPSTDPKQVRRYSQQyvdL-------------- 458  Anaerol...
Q2LW96              560 ---------IIRLVPGLGTRAVD-----RLSDDFPVMLAPGQPg--LRVNTVPEEIKRYSPTkldV-------------- 609  Syntrop...
WP_014857458        562 ---------LLRIVPGLGTRAVD-----RLSDDYPILISPGQSs--IRVNVTPEEVIRYSPKkvdV-------------- 611  Meliori...
EHO41966            561 ---------LVRLVPGLGTRAVD-----RLSDDYPILVAPGQPs--LRANVSLDEIVRYSPRkadV-------------- 610 
WP_015751141        381 -------------V-AEDEVYRW-----------SLSLAQ---------------------------------------- 395  Desulfo...
Q117L5              264 mpipdnllglqafLlPENVQKEF-----------ALRDKY---------------------------------------- 292  Trichod...
jgi:SpiGrapes_1862  703 -------------YhPLekdgpe------nlellDLEEAEkhpeslryiastydretgsltes--irsvghkvitfngil 761 
CDE58667            686 -------------LnPENIVDKFsvddafnlkklTLKEADadgslkfitstydpydmiirdg---yypggrkilsfvnvl 749 
Q2LQG3              593 -------------L-------NIsrnefetipaaDVLSEDmnirselvgvrdyeseeqlker----grggqrkwiltfdg 648  Syntrop...
WP_012175281        554 -------------L-------NLeenrletvsleGLLEKEvpgridlvgvrdteaaqrlrem----grpekahwiltfdp 609  Desulfo...
WP_013561090        459 -------------I-------DLednvfkslpvhEVLDARypplrylaqvdrdgyfeslrsa---lldvtprhlvitfee 515  Anaerol...
Q2LW96              610 -------------I-------NLekntfetveisSFLKSYghlipdvhemvsvykedyvvtpstfdidfehddlivtfeg 669  Syntrop...
WP_014857458        612 -------------I-------NLktnefetieleKLLKEIkrdypafdhvfsvldggmirmps--imdddksdyvvtfeg 669  Meliori...
EHO41966            611 -------------I-------NLktckfetvdivKLLKEHgydypmvekivsvyehgmirnvg-fntnleevdpvvtfng 669 
WP_015751141        396 -------AEEVAHGVRAISRAYDdMIMDTEFCIDk------WDRL--WFVQARPETRW--NEEFEKHPHTIYMRRL 454  Desulfohalo...
Q117L5              293 -------LQLLLEITKKITNEFP-TSFYFKWTLFksd-nheENQL--LITDFKDMQTK--SKKSENSTALTREKQK 355  Trichodesmi...
jgi:SpiGrapes_1862  762 kydafplASIVKDILELGTHAMS-TPIEIEFAVNlnrkapkKPEF--SLLQIRPIAQG--NEENDVQISDMERKES 832 
CDE58667            750 qhdvfplASTLDQLLQIGQKEMG-RPVEIEFAINmnkqdprIATF--YLLQIRPIVDN--KEVMNEDLSVIQQEDt 820 
Q2LQG3              649 llsenpfPQVMQKMLKTLERKYS-YPVDIEFTVNft----rGDSFqiNLVQCRPLQTRgeGKGIQVVIPSDVPESQ 719  Syntrophus ...
WP_012175281        610 flsqtpfVTTMRRLLSRLETVYE-SPVDVEFTVNfa----eNQAMqvNLVQCRPFQGL--DDSVGRRIPETIDRRD 678  Desulfosudi...
WP_013561090        516 llkrtdfAEKMRHILKTLEKNYH-SPVDLEFTLNieyadhtQPHLciTILQCRPQSSL--MPTEVVSLPVNLQPEd 588  Anaerolinea...
Q2LW96              670 likntsfVKKLNGILKTLEDKLK-TPVDVEFAs-------dGKDF--YLLQCRPQSFR--EDGTPAAIPKDIPEKd 733  Syntrophus ...
WP_014857458        670 lfaktdfLKKMDTILKTLQARMK-TPVDIEFVs-------dGNDL--YLLQCRPQSRS--RETSGDPIPKDIPEEK 733  Melioribact...
EHO41966            670 lfqntkfLPQIKQVLKVLQNKLA-TPVDIEFAh-------dGERF--YLLQCRPQSHS--KFSTPAKIPKDLPEEH 733 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap