5CP1,1YZX,1R4W,2IJY,5QNE,4GXZ


Conserved Protein Domain Family
DSBA
?
pfam01323: DSBA 
Click on image for an interactive view with Cn3D
DSBA-like thioredoxin domain
This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyze one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways. This family also contains members with functions other than HCCA isomerisation, such as Kappa family GSTs, whose similarity to HCCA isomerases was not previously recognized. Some members have been annotated as dioxygenases, dehydrogenases, or putative glycerol-3-phosphate transfer proteins, but are most likely HCCA isomerase enzymes.
Links
?
Statistics
?
PSSM-Id: 426200
Aligned: 30 rows
Threshold Bit Score: 90.5654
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
5CP1_A        13 RVDIWSDIACPWCYIGKRRFESALGQFpqr-dqVEVVWHSFELDPSarplnpiamrdglamkysispaqaqgsldhmtqt 91  Deinococcus rad...
2IJY_A        21 VVSEFFSFYCPHCNTFE---PIIAQLKqqlpegAKFQKNHVSFMGG---------------------------------- 63  Vibrio cholerae
P31810        43 EVIEFFSFYCPHCYAFEMEYKIPQQVVdalpkdVKFKQYHVNFLGH---------------------------------- 88  Haemophilus inf...
5QNE_A        21 QVLEFFSFFCPHCYQFEEVLHISDNVKkklpegVKMTKYHVNFMGG---------------------------------- 66  Escherichia col...
P52234        40 QVLEFFSFYCPHCYQFAQVYHIPDAIQkalpadAKLTKYHVDFLGE---------------------------------- 85  Dickeya dadanti...
4GXZ_A        42 TLVNFTDYNCPYCKQLDPMLEKIVQKYp----dVAVIIKPLPFKGE---------------------------------- 83  Salmonella ente...
1_pfamImport   1 TIIAFYDYNCSFCKKGDFSINELLKNDq----kVKVVLRPLPILGD---------------------------------- 42 
Q9A747        94 TVTEFFDYRCGYCRQATPAVLELVQKNp----dIRLVLKDFVIFGN---------------------------------- 135 Caulobacter vib...
O07644        98 TLVEFFDYQCGHCKAMNSVIQAIVKQNk----nLRVVFKELPIFGG---------------------------------- 139 Coxiella burnetii
WP_010909211 114 TIVEFYDYNCGFCKRAIEDMRALTKSDp----dLRFVLKEFPILGP---------------------------------- 155 Mesorhizobium

5CP1_A        92 aaqegleyhfdrvKLA-NTFLAHQLIHYAAEQGqgdAMKERLLRAYMSEGQNVNDLDTLQKLAAEVGLDAGAARAALEAG 170 Deinococcus rad...
2IJY_A        64 -------------NMGqAMSKAYATMIALEVED---KMVPVMFNRIHTLRKPPKDEQELRQIFLDEGIDAAKFDAAYNGF 127 Vibrio cholerae
P31810        89 --------------QSeNLTRAWALAMALGAES---KVKSPLFEAAQKDALKSMDD--IRAIFLSNGITAEQFDGGINSF 149 Haemophilus inf...
5QNE_A        67 -------------DLGkDLTQAWAVAMALGVED---KVTVPLFEGVQK-TQTIRSASDIRDVFINAGIKGEEYDAAWNSF 129 Escherichia col...
P52234        86 --------------LGkELTQAWAVAIALGVED---KVSPLMFDAVQK-TQTVKQPQDIRQVFVAAGVKAEDYDSALNSF 147 Dickeya dadanti...
4GXZ_A        84 -----------------SSVLAARIALTTWREHp--QQFLALHEKLMQKRVYHTDDS-IKQAQQKAGA-----TPVTLDE 138 Salmonella ente...
1_pfamImport  43 -----------------SSEYLARIVLAVYKVNp--NKFKDIHDKLIKIRAVSQES--IKELLIEHGLNYTEIEEIADSN 101
Q9A747       136 -----------------DSEAAARIALGAKDQ----GKSLELHKALMAENALDARG--ALRIAERLGIDMDKAKAVGESQ 192 Caulobacter vib...
O07644       140 -----------------QSQYAAKVSLAAAKQ----GKYYAFHDALLSVDGQLSEQI-TLQTAEKVGLNVAQLKKDMDNP 197 Coxiella burnetii
WP_010909211 156 -----------------DSQKASVVSMAFHLMMp--EKYGEFHNALLGGQGRATEAA-AIKVALSLGADEATLREKMKDA 215 Mesorhizobium

5CP1_A       171 TYAQAVRYDEAQAQQLGITGVPFFVLGG------Ky----GVSGAQAPETLLGALS 216 Deinococcus radiodurans R1
2IJY_A       128 AVDSMVRRFDKQFQDSGLTGVPAVVVNN------RylvqgQSA------KSLDEYF 171 Vibrio cholerae
P31810       150 AVNGLVNKQVNAAEQFKVRGVPDFYVNG------KfrvnpEGL---NYDDFVKDYV 196 Haemophilus influenzae Rd KW20
5QNE_A       130 VVKSLVAQQEKAAADVQLRGVPAMFVNG------KyqlnpQGMDTSNMDVFVQQYA 179 Escherichia coli K-12
P52234       148 VVKSLVAQQEKAAADLQLRGVPAVFVNG------KymiksDGLDTSSMDNYVKQYA 197 Dickeya dadantii 3937
4GXZ_A       139 KSMETIRTNLQLARLVGVQGTPATIIGD------E-----LIPGAVPWDTLEAVVK 183 Salmonella enterica subsp. enterica ser...
1_pfamImport 102 EIKDLITQNIKIARSLRMQGVPTYIINS------K-----LIHGLIDLPQLLNIVQ 146
Q9A747       193 AITQHLADTDALARALNLSGTPAFIVGD------------TLVPGADIDALKLAIE 236 Caulobacter vibrioides
O07644       198 AIQKQLRDNFQLAQSLQLAGTPTFVIGNkaltkfG-----FIPGATSQQNLQKEID 248 Coxiella burnetii
WP_010909211 216 SIPEAFSKTYDLANKLAITGTPSYVVGN------E-----VVFGALGQDVLAEKIK 260 Mesorhizobium
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap