5WMW


Conserved Protein Domain Family
IDO

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pfam01231: IDO 
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Indoleamine 2,3-dioxygenase
Statistics
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PSSM-Id: 426142
Aligned: 177 rows
Threshold Bit Score: 373.407
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5WMW_B                   1 MSKEYHIDEEVGFA-LPNPQENLPD-F-YNDWMFIAKHLpd--------------------lIESGQLRERVEK-LNMLS 56   human
EKM79031               108 AHKDFDIDKHTGFVpARRPLVRLPSa--WKEWEEARDAAvfarlqlaevtekadekqrdkekAETEKWRASIRK-MSVLS 184  Agar...
Q5KJZ4                  59 ASADFEVDVRTGFLpATKNVERLSGe--YEVWEEALDAArgsavggg--------vmlggkrEKDQLWRAGVES-LPVVA 127  Cryp...
KIS68250               166 AAADFDVDVRSGFLpPEAPVRRLSApY-AEHWEHALDLAkriplmhggg----gtkttphqrLLARRWRRSIRE-MPILP 239  Usti...
KDE04431                99 AAADYDVSVATGFLpPDEPVQRLQLgVeWQRFERLLEMAqkevsrl----------vgggvgrLSESWRRHLRE-LPQPP 167  Micr...
WGS:AAWC:PGTG_09355.3   61 ASADFDVDVRSGFLsPSAPLKRISNpV-YQPWEDALETIsksisqta-------dqdqdtklIEIEEWKKFIASeLPVLN 132  Pucc...
XP_007414362            55 AEADYDVDVDSGFLpPQMPLCRLVGeP-WNVWEEAWDSTsgfrpgi-----------gedddqRIRAWRRYIREeMPVID 122  Mela...
EGG02388                55 QSNHPHIDIRSGFLpRLPPIHRIELhP-WSQWEEALDQAkglqlgl-----------gesrnaHTATWRKHIREgLPILS 122  Mela...
EOR02735                47 AAADFDVDPRSAFLpPEEPLRRLSe-C-YDIWELALDSAqnlplll-----------dganneVSNTWRNAICG-MSVLE 112  Wall...
CCF50593               167 AAADFDVDVRSGFLpPEAPIQRLTDlH-EQHWEHALDQAkqiplmqggg----gvnitqhqrILARRWRRSIRQ-MPVLP 240  Usti...
5WMW_B                  57 I---DHLTDH-K-SQRLARLVLGCITMAYVWGk---GhGDVRK------------------------------------- 91   human
EKM79031               185 I---DELKES-KeKLILARHLLTFLLHCYAHTi---P---TIdp------------------------------------ 218  Agar...
Q5KJZ4                 128 T---DDLRAS-LpHLRRAHLVLTFLAHFYVHTtplpG-PSAQKep----------------------------------- 167  Cryp...
KIS68250               240 Ls--DELAND-IrYARRGHVVLSFLAHFYIHSq--pR-KVT-Aalavapqrtwlnmfsrktp--ddlqdeqdladelagk 310  Usti...
KDE04431               168 I---HELTS--LpLLRRAHVVLTYLAHFYTHAvyp--------------------------------------------- 197  Micr...
WGS:AAWC:PGTG_09355.3  133 I---DPLRND-IvEMRRAHLVLAFLTHAFVHSl--sS-NQPSLaet---------------------------------- 171  Pucc...
XP_007414362           123 V---KPLQDQgVvELRRAHSLLAFLTHTYVHSe--aR-KVVLQddy---------------------------------- 162  Mela...
EGG02388               123 VqadDPLANQ-LpLLRRAHLVLAFLVHFYLHSd--qV-NDDEEeegs--------------------------------t 166  Mela...
EOR02735               113 P---PTILSDgIrSVRRAYTVLSFLAHFFVHSq--pA-HKKQTtqs---------------------------------- 152  Wall...
CCF50593               241 Ls--DQLAND-IrYARRGHLVLSFLAHFYIHSq--pR-KSQDAalvvapqqpswlnlfsrnkspeelqddqdladelagk 314  Usti...
5WMW_B                  92 ---VLPRNIAVPYCQLSKKLELPPILVYADCVLANWkkkdpnkplTY---ENM--DVLFSFRDGDCSKGFFLVSLLVEIA 163  human
EKM79031               219 --iVIPRSISVPLLQTSKILQHPPVLTYFDENLNNWdcpe--ngkFPpsiNDL--RCRTTFTGTTDEAEFHLTLTRIELR 292  Agar...
Q5KJZ4                 168 --tSIPPCISIPLLAVSPLLGLPPILTYADTVLWNFlpln--sliAPsafSNPpnRIITTFTNTRSEEQFYLISALCEIA 243  Cryp...
KIS68250               311 ymrRLPAAIAVPWVQLSQKLDLPPVLTYATTVLWNWdyi---dpsRGlepDNL--SIVETFTATPSEHHFFFTSLLIEAR 385  Usti...
KDE04431               198 ydtHVPATVSVPLVEISESLGLPPILTYADTVLWNWhll---drsRGiqaDNI--VITTTFTSSDSEKAFFFLSILCELH 272  Micr...
WGS:AAWC:PGTG_09355.3  172 -qtLIPLSLAVPFSAISLALDMPPVLTYADTVLYNWsfk---eprLGftaENV--EIPTTFTRSDSERHFYKTSVLVEAL 245  Pucc...
XP_007414362           163 -qvIIPRALAIPFCAVSDILDIPPILTYADTVLYNWklk---nqaLGftvDNV--EIPSTFTRSVSESHFFKTSLLIETI 236  Mela...
EGG02388               167 ktvLVPSSLALPFCAVSQLLDIPPVLTYSDTVLYNWtli---npaNGftsENV--KILTTFTGTKDEEHFYKTSVLIESL 241  Mela...
EOR02735               153 -tqIIPRSIAIPWHTTALALGLPPILTYASTVLWNWeyi---dksKGlrrGNL--RAPLTFTQSRDEEHFYLTSAHIEVE 226  Wall...
CCF50593               315 hmrRLPAAISVPWVQLSQKLDLPPILTYATTVLWNWnyl---dpsRGlqpDNL--RIVETFTGTPSEHHFFFTSLLIEAR 389  Usti...
5WMW_B                 164 AASAIKVIPTVFKAM---Qmq---eRDTLLKALLEIASCLEKALQVFHQI----------HDHVNPKAFFSVLRIYLSGw 227  human
EKM79031               293 GGEALELMRLALVEAvhgNen---gPAKVTDYLERATIVIQELREILLRI----------KNLMDPDLFYNKIRPWLSG- 358  Agar...
Q5KJZ4                 244 GAEALGLMRQSLDELfiaDek---aLRRVTIYLKKLADQIDRISDITMTL----------MNEVDPEEFYHLIRPWFRG- 309  Cryp...
KIS68250               386 GVEALELMRVSLDEAfvaDrv---aRRRIAGYLNRLAVVIKSLTKLLHDV----------RNGCDPKIFYWGIRPWFVG- 451  Usti...
KDE04431               273 GPIILRSMSSTLDEAffaDrt---aLVRIAGHLDNIASALDELALLLHDStrgafgpapvRASISAPVFYWEIRPWFNG- 348  Micr...
WGS:AAWC:PGTG_09355.3  246 GPECLKLMRSSLDEAfmeDei---sVKRIGNNLGRLAKQIDRISKVLSDV----------RAGCDPRTFYWEIRPWFIG- 311  Pucc...
XP_007414362           237 GPQCLRSMRSSLDEAfigDek---sVRRIGEHLVALVINIKCITSFLNDV----------RTACDPREFYWEIRPWFNG- 302  Mela...
EGG02388               242 GPMCLSLMRSLLDEAllaDql---sFARISANLSLLASIIDQITVLLEKV----------RDDCQPACFYWLIRPWMNG- 307  Mela...
EOR02735               227 GRLCLERMSQCLDEAfmaDvspqvsFPRMCRQLTDLAAQINVLTEILVAV----------RAECSPEVFYTSIRRWFNGp 296  Wall...
CCF50593               390 GVEALELMRVSLDEAfvaDrv---aRRRIAGYLNRLAEVIKDLTKLLHDV----------RKGCDPKIFYWGIRPWFVG- 455  Usti...
5WMW_B                 228 --kGNPQ---LSDGLVY--EGf---------------------wEDPk---eFAGGSAGQSSVGQCFDVLLGIQQT---- 272  human
EKM79031               359 ---GDGDt--GGRLWIF--EGkdev----------------gewPGLs---eLSGLSAAQSPIIQALDAYLGIESArg-- 410  Agar...
Q5KJZ4                 310 ---GDADg-pGSVGWDY--LGlaadnanvva----gtheaesasTEGrrgklFSGPSAGQSSLIHAIDIFLTVDHSptee 379  Cryp...
KIS68250               452 ---SDTVdkgEEAGWHF--EGvdp-----------------egiKRV-----FSGPSAGQSSMIHAIDVFLDVDHTrrkq 504  Usti...
KDE04431               349 ------------GRWMY--ESvge--------------------------reYGGPSAGQSSLVHAVDLFLGIDHSprpa 388  Micr...
WGS:AAWC:PGTG_09355.3  312 ---GR---------WIW--EGvqieennkgktaeqareflaeskWKEt---eYGGPSAGQSTLIHAIDVFLGVDHEpn-- 372  Pucc...
XP_007414362           303 ---GK---------WIM--EGvpal----------------pgpWRVt---eFGGPSAGQSTLIHSLDVFLGVDHS---- 345  Mela...
EGG02388               308 ---GT---------RQMgsDGv------------------------Vv---kWGGPSAGQSTLIHSLDVFLGIDHRpr-- 346  Mela...
EOR02735               297 ngeGK---------WHY--EGvd-------------------plGVYr---dYGGPSAGQSSLIHAIDAFLGVNHA---- 339  Wall...
CCF50593               456 ---SDTVdkgEQVGWHF--EQvdp-----------------egvKRV-----FSGPSAGQSSMIHAIDVFLDVDHTrrke 508  Usti...
5WMW_B                 273 ----------------A--------------------G---------------------GghaAQFLQDMRRYMPPAHRN 295  human
EKM79031               411 ---------------kGs-------------------Ya-------------------tAsgkKPFLERMRSYMALGHRK 437  Agar...
Q5KJZ4                 380 erreameaaenrpeqsGvfikmnsspvnastapsaskPhghshgsiappvsnsnpsaaaPkseATFLQRMLAYMPLPHRS 459  Cryp...
KIS68250               505 rl--------hrpaatTn-------------------Ad-------------------aRgadATFMERMSLYMPGHHRA 538  Usti...
KDE04431               389 sttstasvpaslgpepStt----------------lpTpva---------------qakGlsdDTFMMRMSTYMPGHHRA 437  Micr...
WGS:AAWC:PGTG_09355.3  373 --------------lqEl-------------------Ss-------------------gIqdeETFMNRMSTYMPHHHRL 400  Pucc...
XP_007414362           346 ----------------Pr-------------------Pg-------------------eMskeETFMKRMAAYMPHFHRR 371  Mela...
EGG02388               347 ---------------pTe-------------------Gh-------------------sTsheSTFMERMAAYMPHHHRN 373  Mela...
EOR02735               340 ----------------Pv-------------------Dd-------------------eAdfdDTFMRRMQTYMPDYHRR 365  Wall...
CCF50593               509 rlnr-----paatangGg-------------------Gd-------------------aRgadGTFMERMSLYMPGHHRA 545  Usti...
5WMW_B                 296 FLCSL--------------------------------------------------------ES-NPSVREFVLSKGDAg- 317  human
EKM79031               438 FLSEL--------------------------------------------------------RAyPRQIRTYVQTIAEQqg 461  Agar...
Q5KJZ4                 460 FLIHL--------------------------------------------------------SThPTPLRPLVLHFAAShp 483  Cryp...
KIS68250               539 FLSHLrnisfddadqdqdeelq----------------------dlepreansdadgeqqlRElPHPIRSLALKAKSEeh 596  Usti...
KDE04431               438 FLAHLaslyqpt------------------------------------------evseagiAEkLPSVRDLVIRHPQQ-- 473  Micr...
WGS:AAWC:PGTG_09355.3  401 FLKQLsrsc-------------------------------------------------ltqRGqPNLIRSIVINHQDQkf 431  Pucc...
XP_007414362           372 FLQHL--------------------------------------------------------FSyTGEIRSLVLSSGSKs- 394  Mela...
EGG02388               374 FLQHLsqtlspnsh---------------------------------------ltifpqlpNQiTHSVRSLASIASPDs- 413  Mela...
EOR02735               366 FLNHL--------------------------------------------------------KCvEPSCRDVVGTSHNAd- 388  Wall...
CCF50593               546 FLSHLrnisfddgeddeedqegqdhgvatmsnsvatlsasristpatttidaesdsedeapRElPHPIRSLALAAKTEeh 625  Usti...
5WMW_B                 318 ------LREAYDACVKALVSLRSYHLQIVTKYILIPASQ----------------------------------------- 350  human
EKM79031               462 s--dsaVVHAYNIAVKALKDLRDSHMVIVTLFVIGPARRvknea------------------------------------ 503  Agar...
Q5KJZ4                 484 -----tLVQAYDGALESLRRFRERHMRVVSKFIVQQARRkpgerir---------------------------------- 524  Cryp...
KIS68250               597 d---egLPAAYDNALQELKALRDEHMKVAYLYIVAQARGsppdayaplakgftgepn----------------------- 650  Usti...
KDE04431               474 ------LQESYDRAVLSMKKFRDEHMKLATVYIVAQAKKepgrqtvfwqew----------------------------- 518  Micr...
WGS:AAWC:PGTG_09355.3  432 ksgpnnLKENYNLCIQSLENLRKTHTQIVSLFIICQKNSsppdqlsalnsterthpssstapcnqsvshvdsldeklkdl 511  Pucc...
XP_007414362           395 -----lLATRYNSAVAALEELRNSHSRVALFYIISQSRTeppigsafise------------------------------ 439  Mela...
EGG02388               414 -----sLFSAYNQSVQSLLKLRATHSKIALWYVLSQSRIeppl------------------------------------- 451  Mela...
EOR02735               389 ------LQSAYNGAIESMKKLRSEHIKIATLYVVTQSRKae--------------------------------------- 423  Wall...
CCF50593               626 d---egLPAAYDNALQQLKSLRDEHMKIAYLYIVAQARGsppdayaplpkgftgepavd--------------------- 681  Usti...
5WMW_B                 351 ------------------------------QpkenktseDPSKLEAKGTGGTDLMNFLKTVRSTTEKS 388  human
EKM79031               504 --------------------------aameAgsapsardEGKNDQVKGTGGTELVKFLKGVREQTADA 545  Agaricus bisporu...
Q5KJZ4                 525 ------------------------rltgmeMeddedestMANAGELRGTGGTALFKFLKRCRDNTTKA 568  Cryptococcus neo...
KIS68250               651 ------------vdrrlaakakahadaeaeAraildtnsKDNGGGAKGTGGTDLVTFLRDCRVNTIDA 706  Ustilago maydis 521
KDE04431               519 ------------------edkriekerlrqEea------rGRRDVLKGTGGTDLIVFLKMCRERTKEA 562  Microbotryum lyc...
WGS:AAWC:PGTG_09355.3  512 tnrngntkqqenpnklleerstdnhtqpepTavkladhgESQREILKGTGGTDLSKFLKRCKLRTTQA 579  Puccinia gramini...
XP_007414362           440 --------------------weekmvaewkKqqlalsrePGNETVHTGTGGTDLAKFLKRCRERTTEA 487  Melampsora laric...
EGG02388               452 --------------------------nspfLkqweksreLKKRSVQLGTGGTDLARFLKRCRERTSEA 493  Melampsora laric...
EOR02735               424 ----------------------------keSdsnsanvpESRDTDIKGTGGTSLIKFLKTCRDRTHST 463  Wallemia ichthyo...
CCF50593               682 -----------rrlaakakaahadaeaeaeAdaaldtnsEDNGGGAKGTGGTDLVTFLRDCRVNTIDA 738  Ustilago hordei
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