2G3N,4KMQ,2XVG


Conserved Protein Domain Family
Glyco_hydro_31

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pfam01055: Glyco_hydro_31 
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Glycosyl hydrolases family 31
Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.
Statistics
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PSSM-Id: 460044
Aligned: 659 rows
Threshold Bit Score: 247.087
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2G3N_C        148 YVIE--GP---RIEDVLEKYTELTGKPFLPPMWAFGYMISRYsYYPQDKVVELVDIMQKEGFRVAGVFLDIHYMD--SYK 220  Saccharolobus...
WP_025336249 1499 YFIA--GDtggSLNSIMKSFSSLTGTAPIPPMWALGYMQSRFgYRSWNEVDGIVDTFRSKDIPLDSMVLDVYWAKknHYF 1576 Paenibacillus...
CDF78716      333 YLVA--GE---NPEAVISEYQKLTGTSPLFAKSAYGFWQCRErYHNQEELLANAREMRERKIPFDNIVQDWFYWPe-GTK 406 
CDA06274      227 FIR---GE---NLDEIIKGFRLLTGRAVMLPKWSFGYVQSKEaYKTQDEVVGIAKKYRDLDIPLDCVVQDWNTWEpgKWG 300 
WP_003527800  233 FIH---GS---TLDDIIKGYRTLTGNAPLLPKWAYGYIQSKEaYRTQEELVATAAEYRKKGIPLDCIVQDWNTWEpgKWG 306  [Clostridium]...
CCX66778      248 FLAGedGRf--RMEGVVAAYRKLTGKAALLPRWCFGYLQSKErYCSQEELLSVAETYRKKHIGLDGVILDWCSWKdgQWG 325 
CDF08225      241 FIN---GE---SMDGVIAQYRSLTGKTTILPRWAYGYIQSQErYETKKEILDTVKEYRERNIGLDGIVLDWCSWKgnLWG 314 
CDC44651      250 FIA---GE---TLGETVKGIRKLTGKAVLLPKWAYGYIQSQErYETAEELVKTAEEFRRREIGLDALVLDWMSWEgnLWG 323 
WP_013280416  229 FIP---GT---VTTDVIKGFRKLTGRASMLPKWAYGYIQSKErYKTQEEMLEVAKEFRRRKIGIDCLVLDWLSWEdgKWG 302  Butyrivibrio ...
WP_015924523  242 FIR---GE---SFDQIIGGYRQLTGRASMLPLWAFGFMQSQErYETQQEIIDTVKRYRELGVPLDGIVLDWQSWEegMWG 315  Ruminiclostri...
2G3N_C        221 LFTW---HPYRFPEPKKLIDE-LHKRNVKLITIVDHGI-RvDqnYSPFLSGM--GKFCEIESGELFVGKmWPGTTVYPDF 293  Saccharolobus...
WP_025336249 1577 DMTWnddPAQDFSSPKANMAE-LQEKGVNIVTIVDPYIqV-T--ASNFKEGDskGYFVKDASGKTVIYPaWYGKAGLIDF 1652 Paenibacillus...
CDF78716      407 GPEW---DPVKYPDPDAMVDE-LTRLNLNLMVSVWPEV---K--N---EPLEkkYGLTK-I-------E----SSNYVDI 462 
CDA06274      301 NKRV---DRERYPSLTEMNQK-LHDMHVHSMVSVWPNM---NsgTEDYEEMKaaGHLFY-D-------Y------ATYNA 359 
WP_003527800  307 NKHL---DLSRYPNIREANRQ-LHEMHVHSMVSIWPNM---NmgCADINEFLeeNLLLG-D-------A------STYDA 365  [Clostridium]...
CCX66778      326 QKTL---DPERFPD-AAVMNHaLHLQNVHSMISIWPNM---DesCPDYQEMReqGCLLP--------------ASHLYDA 384 
CDF08225      315 QKTF---DETRFPDPDDMMEQ-LHEAQVHFMLSIWPNM---DqeTENYKEFAerQLLLP-G-------C------SIYNA 373 
CDC44651      324 QKTF---DKIRFPNPKEMIEK-LHEKNIHFMISIWPNM---NenCENYREFQerNLLLP-A-------S------DIYNA 382 
WP_013280416  303 QKSF---DKSRFPTPKEMTDE-LHRMGIHFMMSIWPNM---SpnTEDNAEFKalNLLLP-G-------T------DIYNA 361  Butyrivibrio ...
WP_015924523  316 QKTF---DTERFPDAKNMMEQ-VHELGAHLMISIWPNM---VehCENYKEMKanNGLFQ-R-------S------EIYNA 374  Ruminiclostri...
2G3N_C        294 FREDTREWWAGLiSEWLSQ-GVDGIWLDMNEPTDFSrAIEIrDVLSSLPVQFRDDrlvttfpdnvvhylrgkrVKHEKVR 372  Saccharolobus...
WP_025336249 1653 TNPEAAKWYSSQ-VKKLHDaGVKGYWIDLNEP-EQPtDSLR-DQFA---A--G---------------------SAAEIT 1703 Paenibacillus...
CDF78716      463 YDEKVSENFYRAlSDSMFHkGVKSIWLDGTEPEGVKnTKVN-TAI----G------------------------PYESVQ 513 
CDA06274      360 FSEEARELYWKQaEKELFSgGFDSWWCDSTEPFSGPdWNGEfKREPWERFRLVGDehrr-----------flgAE---RA 425 
WP_003527800  366 FQEKARDLYWRQaDAELFQgGFDSWWCDSTEPFSGPdWGGEtLREPWERYSLVGGehkk-----------yldPA---CA 431  [Clostridium]...
CCX66778      385 FDRRARELYWEQtRRELYRsGFDAFWMDSSEGVT---PEWGhSIKPEPWQMMQEFlmv------------agaYMPEKLT 449 
CDF08225      374 LSAEGRQLYWEQvKRGLYAhGVDAWWCDSSEPFTPEwNHVErTEPAKMYAEYCETten------------hlpAE---KT 438 
CDC44651      383 FSEEARKLYWEQvKRGLFChGVDAWWCDSSEPFTPEwSRLYkPDPSEMYRDFVDVagk------------smpIE---KG 447 
WP_013280416  362 FDEKARNLYFSQvERNLLPsEVDAFWCDSSEPITPEwEHHIePEDGEKYCEFKTDagn------------impLE---MA 426  Butyrivibrio ...
WP_015924523  375 FSSEARKLYWKQaKEGLFSkGVDAWWCDSSEPFTPEwNNPVkPEPDQNLTAFHNTcrt------------ymdEV---YT 439  Ruminiclostri...
2G3N_C        373 NAYPLYEAMATFKGFRTShr------neI-FILSRAGYAGIQRYA-FIWTGDNTPSWDDLKLQLQLVLGLSISGVPFVGC 444  Saccharolobus...
WP_025336249 1704 NVYALNEAKAFYDGQRSYtg-------dRvWTLARSGFTGIQQYGtTVWSGDIDASWVSFSHQLQLGLSAAASGISYFTN 1776 Paenibacillus...
CDF78716      514 NPYSLLVTKAMYEGRRKEfp------keRvFNLTRSAYAGQQRYGaTSWSGDVEASWEQFEEQIAAGLNFTMAGVPYWTH 587 
CDA06274      426 NLYAAAHAQGIYENQRKSnp------dkRvLNLTRSGYASSQKFGtVLWSGDIFASWDTMKKQIHEGLNMCMSGMPYWTL 499 
WP_003527800  432 NLFALKHAQGIFEHQKKQap------ekRvVNLTRSGYAGSQQYGtILWSGDISANWDTLRRQITEGLNFCMSGLPYWTL 505  [Clostridium]...
CCX66778      450 NAYSFFHALGVYEHFKRSekrrkqgsqrRpVILTRSATIGQQRYGcILWSGDTGASWETLRAQVLQVQSFSLSGFPYWCV 529 
CDF08225      439 NAYALYHAQGIYEGQRGEqdn-----ekRvFNLTRSAWTGQQRFGtVLWSGDIEASWETLRKQIAAGLHFSASGLPFWTV 513 
CDC44651      448 NAYGLYHAQALYEGQRSVte------dkRvVNLTRNGYLGSQKYGtILWSGDTYASWETLRRQIVAGLQFCISGLPYWTL 521 
WP_013280416  427 NSYGLYHAMTIWDGLRRIrp------dkRvVNLTRSGWAGSQKYGtILWSGDVSASWDCLRKQVRAGLQMAASGMPYWTL 500  Butyrivibrio ...
WP_015924523  440 NAYPYMHAKTIYEGQRETdg------qkRvVNLTRSGYTGIQKYGtILWSGDTSAKWSTLKNQIAAGLNYCASGLPYWTM 513  Ruminiclostri...
2G3N_C        445 DIGGF--------------------------------Q--GRnfaeidNsMDLLVKYYALALFFPFYRSHKAT------D 484  Saccharolobus...
WP_025336249 1777 DTGGFn-------------------------------GkpSP---------ELYTRWMQAASLMPIFRSHVALgdnpsdP 1816 Paenibacillus...
CDF78716      588 DIGGFfrdsnsin-----------------pefdnqyT--NP------EfIELLTRWFQFGTFSPIFRIHG--------- 633 
CDA06274      500 DIGGFftvnenwqhrgcscskdptpkwfwrgdyeegvE--DY------GyRELYVRWFEQGVFLPMFRSHGT-------- 563 
WP_003527800  506 DIGGFfvvgtdytkrgcgcndnpnplwfwsghynggcE--DL------GyRELYTRWLEYGVFLPIFRSHGT-------- 569  [Clostridium]...
CCX66778      530 DIGGFfvkrgepwy--------------wggeypqtwK--DP------AyRELYVRWFQFGAFLPIFRAHGT-------- 579 
CDF08225      514 DIGAFfvkngnlwf--------------wkghydagtE--DL------GyRELFVRWYQWACFLPVFRGHGT-------- 563 
CDC44651      522 DIGAFfvksgmpwf--------------wkgeyeggnT--DP------AyRELYVRWLQYGAFLPIFRSHGT-------- 571 
WP_013280416  501 DAGAFfvkrgfqwy--------------wngdydginE---D------Y-KKLYTRWLEFAAFLPIFRSHGT-------- 548  Butyrivibrio ...
WP_015924523  514 DIGAFfvkqghmwf--------------wdgdyeggcS--DL------GyRELYTRWYQLGAFLPVFRSHGT-------- 563  Ruminiclostri...
2G3N_C        485 GIDTE--PVFLPDy------YKEKVKEIVELRYKFLPYIYSLALEASEKGHPVIRPLFYEFQDDDDMYRieDEYMVGKYL 556  Saccharolobus...
WP_025336249 1817 TNIRE--PWAFGAe------AEASVTKAINQRYQLLPYIYSTAKQTADGEASLMKPLVMDYANDSNVYNiqDQWMFGGSI 1888 Paenibacillus...
CDF78716      634 -YVSEteIWRYDDa------FESTARKFIDLRYQLMPYIYSQAWQITTNSKQLMSPLAYFYPEDKKTWGikDQLIFGESF 706 
CDA06274      564 DTPRE--VWNFGRpg---epFYDALVKNIELRYRLMPYIYSNAARIWTDDYTMMRSLLFDFAQDKRAAAlgDEYMFGDSL 638 
WP_003527800  570 DTPRE--IWNFGEpg---spFYDAIEKFIRLRYRLLPYIYSLAASVTFRQDTVLRSLLFDFSEDTAARQvsDEFMFGRSL 644  [Clostridium]...
CCX66778      580 DCSRE--VWQIKRqegknspSCDALIGTIRLRYFLLPYIYSEAGKTWLEDGMLIRPLVSAFPDDRTAREaqYQYLFGPSL 657 
CDF08225      564 DCRRE--LWHFENte---ipFYDVLVQMNHLRYTLMPYIYSCAGLCWLKDRSMMKLLAFAYPEETAVFHimDQYLFGEEL 638 
CDC44651      572 DCRRE--PWNFGDkg---dpFYEAILSAIRLRYQLLPYIYSVAGAIWLEDETMMRPLIMDFPEDSHVVEisDEYLFGPSL 646 
WP_013280416  549 DVSRE--PWAFGDag---dkYYEAIVSAIKGRYRLFPYIYSVGAMACIRDDMIIRPLFFDYPEEENICEisDQYMFGPSL 623  Butyrivibrio ...
WP_015924523  564 DCRRE--IWNYGKkg---efFYDAIEKITHLRYQLMPYIYSLAGMVSQKHGTILRLLAFDFINDAKVYDidDQFMFGPSL 638  Ruminiclostri...
2G3N_C        557 LYAPIVsKE-------------ESRLVTLP-RG-KWYNYwngeii--ngksvVKST-HeLPIYLREGSII 608  Saccharolobus solfataricus
WP_025336249 1889 MAAPVNkEGa------------SQRMVYLP-SG-TWYDWnseqkfnggheitYNADlNtIPMLVKEGAII 1944 Paenibacillus sabinae
CDF78716      707 MVGFVTeYKs------------REMSMYFP-KG-QWYNYwtnqiieggkevtVKANlDeTPLFVKAGSII 762 
CDA06274      639 LVCPVTePMyyeres-raidreKLWNCYLP-AGtKWYDFhtlkeyeggteveADASlDhIPVFVKAGAVI 706 
WP_003527800  645 LVCPVYqPMyydags-vplekeRKRTCYLP-SGcTWYDFwtnepydggqsitADAPlDkIPVFVRSGSLI 712  [Clostridium] innocuum
CCX66778      658 MVCPVLnPGi------------REMEVYLPrGT-GWYDWhtsqrfeggqwirTETQyDrIPLFVMEGAII 714 
CDF08225      639 MVCPVTePMyygensseltdtvKTRRVYLP-EAhGWYDYwtntyyeggqwieVCASiDrIPLFVKEGGIL 707 
CDC44651      647 LICPVMtPMyyqtggaalekvqYTRRVYLP-EGtDWYDLytrekyeggqeieANADiEhIPVYVRAGAIL 715 
WP_013280416  624 MVCPVL--Ded----------dK-LSIYLP-AGnDWYDYytgdfyeggrtidYKCPiDrIAVFAKAGSII 679  Butyrivibrio proteoclas...
WP_015924523  639 MVCPVTaPMyyeadskpiegvaKTRKVYLP-AGsDWYDFwtekrfkggqsieAEAPiDrIPIYVKAGSIL 707  Ruminiclostridium cellu...
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