pfam01004: Flavi_M (This model is not part of the current CDD release)
Flavivirus envelope glycoprotein M
Flaviviruses are small enveloped viruses with virions comprised of 3 proteins called C, M and E. The envelope glycoprotein M is made as a precursor, called prM. The precursor portion of the protein is the signal peptide for the proteins entry into the membrane. prM is cleaved to form M in a late-stage cleavage event. Associated with this cleavage is a change in the infectivity and fusion activity of the virus.
Jiyao W et al.(2023). "The conserved domain database in 2023.",