1VPX


Conserved Protein Domain Family
TAL_FSA

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pfam00923: TAL_FSA 
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Transaldolase/Fructose-6-phosphate aldolase
Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA). They both belong to the class I aldolase family. Their protein structures have been revealed.
Statistics
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PSSM-Id: 395737
Aligned: 122 rows
Threshold Bit Score: 136.129
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1VPX_K         15 IFLDTANLEEIK-----KGVEwgivDGVTTNPTLISK--------E-----GA-EFKQRVKEICDLv------------- 62  Thermotoga mar...
KIS71595       71 LFHDMTSNQIIVlstysELLT----NDKNKAAKLVEMcvaaakqiKggmwnGKqLSSTVLERISVDgltgaesdeekhqq 146
O32335          3 LIIDDVNIEKIK-----DVFSifqiDGVTSNPSILHK--------Y-----GK-QPYEILIKIREFig------------ 51  Clostridium be...
WP_003790462    3 ILIDHANVDSIA-----KTLEylpiDGVTTNPTILYR--------E-----GK-EPLEVLHAIKQLlp------------ 51  Schaalia
tigr:CLI_3594   3 ILLDTANIESIK-----NINDiyplDGVTTNPTIISK--------E-----KK-DFIGILREIRNVig------------ 51 
WP_006071774    3 YMLDTANLDAIK-----KAVDlypiAGVTTNPTIIAK--------E-----NR-SLRDIILDIRELig------------ 51  Vibrio
Q32IB1         27 LYLDTSDVVAVK-----ALSRifplAGVTTNPSIIAA--------G-----KK-PLEVVLPELHEAmg------------ 75  Shigella dysen...
Q6D0M2          3 FYLDTADVAAVE-----RLAGvlpiKGVTTNPSIVAR--------G-----KS-DIYSVLRDMQAVig------------ 51  Pectobacterium...
jgi:Asuc_0438   3 LYLDTANLETIK-----KFHRtlplQGVTTNPSILAK--------E-----KQ-PVAETLQAIQQIig------------ 51 
WP_009792840    3 LVIDSANIESIK-----KLVEyfpiDGVTTNPSIVVK--------E-----QK-PFLPLLKEIRAVig------------ 51  Bacillus
1VPX_K         63 --------------------KGPVSAEVVS---LDYEGMVREARELAQISE----------YVVIKIPMTPDGIKAVKTL 109 Thermotoga mar...
KIS71595      147 lasdiltvhfglemlpnllaSGNLHAQTATsqaYNASATVRHARRFVALYElisgdtvdssRVCIKIPTTIAGLQAMRFL 226
O32335         52 -------------------eNSELHVQVIS---ESSEGMLKEAHKIIKELGk---------NTYVKIPVTRDGLKAIKIL 100 Clostridium be...
WP_003790462   52 -------------------dGAQLHVQIVS---QRADDMVAEARALRGEIGg---------NLFIKLPVTREGFAAIPRI 100 Schaalia
tigr:CLI_3594  52 -------------------eEKMLHVQVIG---SKAEDMIEEAVYLNEKIGg---------NLYIKIPVTEQGIKAMKKL 100
WP_006071774   52 -------------------sERMLHAQVVG---DTAEVMLEEAKALR-KLDp---------EIIIKVPVTPQGIKAMKLI 99  Vibrio
Q32IB1         76 -------------------gQGRLFAQVMA---ITAEGMVNDARKLR-SIIa---------DIVVKVPVTAEGLAAIKML 123 Shigella dysen...
Q6D0M2         52 -------------------aEGQLFAQVMS---RDPDVMVEEALKLR-EVIp---------SLVVKVPVTHAGLRAIKQL 99  Pectobacterium...
jgi:Asuc_0438  52 -------------------eNGQLFAQTLG---RSAREMIDDALALR-EIVp---------TIAVKIPVTPEGLVAIKEL 99 
WP_009792840   52 -------------------eEKELFAQTIA---GDAEGMGEEARWLCEAVSg---------NVVVKIPVTMEGIKAIKML 100 Bacillus
1VPX_K        110 SAEG---------------IKTNVTLVFSPAQAILAAKA-GATYVSPFVGRMDDLSn---------------DGMRMLGE 158 Thermotoga mar...
KIS71595      227 SSGGildennvggpllegkIQVLATTVFAVEQGLAAAQAaGATYVAPYINALAAHFfdaenpsaedkqkaldAGGRSISE 306
O32335        101 RKEE---------------INVTATAIYTQMQAYLAGKA-GAQYAAPYVNRIDNLGa---------------NGVQVAKD 149 Clostridium be...
WP_003790462  101 VREG---------------MQVTATGIHSSMQGFMAAKA-GARYVAPYVNRMDNYGi---------------DGVRVASE 149 Schaalia
tigr:CLI_3594 101 SKEG---------------YKITATAIFTAQQALMAAKA-GAEFVAPYVNRIDNLMg---------------DGIKVVSD 149
WP_006071774  100 SAEG---------------IRITATAILTPQQALMAAMA-GAEFLAPYVNRLDNICg---------------DGTLVAAE 148 Vibrio
Q32IB1        124 KAEG---------------IPTLGTAVYGAAQGLLSALA-GAEYVAPYVNRIDAQAg---------------SGIQTVTD 172 Shigella dysen...
Q6D0M2        100 TELD---------------IPTLGTAVYGAGQGFYAALA-GARYIAPYVNRIDAQGg---------------DGIALVKE 148 Pectobacterium...
jgi:Asuc_0438 100 TRLS---------------VPVLGTAVYGAAQGFLAALA-GAVYIAPYVNRIDAQGg---------------SGIDVVRE 148
WP_009792840  101 KAEG---------------IRTLATTVYTPMNAYLAAKA-GADYVAPYVNRIDNLTg---------------NGAKVVAE 149 Bacillus
1VPX_K        159 IVEIYNNY-G-------F-ETEIIAASIRHPMHVVeaALMGVDIVTMPFAVLEKLFKhp--------mtDLGIE---RFM 218 Thermotoga mar...
KIS71595      307 IIYPLQRClRrmrqqnnKiKTKVMAASFINAEEAI--ELCGLDHVTLGAGIVQALATtkltdgivetmhQASDKmriAEE 384
O32335        150 IHDIFEKN-N-------F-KTEVLAASFKNSQQVLelCKYGIGAATISPDVIEGLIKnd--------cvDVAVE---NFK 209 Clostridium be...
WP_003790462  150 IHRTLRSY-D-------L-KADVLAASFKNSEQVLelVRQGVGAITAAPDVLAALIKnp--------atDAAIA---DQN 209 Schaalia
tigr:CLI_3594 150 IVNIFEIY-N-------I-NSKVLAASFKNTEQIHnaCLKGAHSVTVNEDLIKQLIYhp--------ltDLSVD---NFV 209
WP_006071774  149 MAHLIDVY-N-------L-DAKVLAASFKNVQQVHevAKAGVQSVTIAPDVFDQLLVhp--------ltDSGVA---GFM 208 Vibrio
Q32IB1        173 LHQLLKMH-A-------P-QAKVLAASFKTPRQALdcLLAGCESITLPLDVAQQMISyp--------avDAAVA---KFE 232 Shigella dysen...
Q6D0M2        149 LQTLINLH-S-------P-QTQVLAASFRTPRQVLdcLLAGCQAITVDPAVAELFLQdp--------avDDALN---RFD 208 Pectobacterium...
jgi:Asuc_0438 149 LQALLDQH-A-------P-DSLICAASFRTPRQALdcLLAGCQSITLPPDIALAFLNdp--------avFAAVE---KFE 208
WP_009792840  150 ITEIFSKH-N-------L-SCEILAASFKNVQQIHnvCLAGSHGITASPELIEALVNip--------siEDNVK---AFR 209 Bacillus
1VPX_K        219 EDWKKYLENL 228 Thermotoga maritima
KIS71595      385 KELERYCATL 394
O32335        210 KDFEILCGQG 219 Clostridium beijerinckii
WP_003790462  210 RDFGFLVGER 219 Schaalia
tigr:CLI_3594 210 KDWENQYGKN 219
WP_006071774  209 SDWHGAYGEG 218 Vibrio
Q32IB1        233 QDWQGAFGRT 242 Shigella dysenteriae Sd197
Q6D0M2        209 HDWQARFGHA 218 Pectobacterium atrosepticum
jgi:Asuc_0438 209 ADWQNAYQRS 218
WP_009792840  210 QDWMGQYGEG 219 Bacillus
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