1ZFN_A 11 YSRQILl-dDI-ALDG----QQKLLDS-QVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDI-- 81 Escherichia coli Q9UBE0 19 YDRQIR---LW-GLEA----QKRLRAS-RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV-- 87 human Q82IR6 104 LRPDLAslsLVaRAPGagiqRLAARRSlRVQVRGAGRVGVVLASLLAGAGVGEVDVQDTGRVEPWDVAPGGL-PAESI-- 180 Streptomyces avermit... O95352 335 LNLKLMcwrLV-PTLD----LDKVVSV-KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDClg 408 human Q6CBC3 281 LNLKLMkwrIA-PELD----LDTIKHT-RCLLLGAGTLGSYVSRSLLAWGVEQVTFVDNGTVSFSNPVRQPLYKYVDCld 354 Yarrowia lipolytica ... P38756 57 LARNYA---FL-GEEG----MRKIKEQ-YIVIVGAGEVGSWVCTMLIRSGCQKIMIIDPENISIDSLNTHCCAVLSDI-- 125 Saccharomyces cerevi... O13861 109 LARNYA---FF-GEDG----MERLRNS-FVIVVGCGGVGSWVINMLARSGVQKIRIVDFDQVSLSSLNRHSIATLQDV-- 177 Schizosaccharomyces ... Q6C125 72 LARSRV---FF-GDDG----LEVIRKS-SVVIVGAGGVGSWAATMLLRSGVGNVRLVDFDQVTLSSLNRHATASRAHV-- 140 Yarrowia lipolytica P95234 25 FCRNLG---LI-SPTE----QQRLRNS-RVAIAGMGGVGGIDMVALARMGIGKFTIADPDVFEIRNSNRQYGAMRSTN-- 93 Mycobacterium tuberc... Q72WQ5 315 FSRNLG---LV-DYAG----QRRLLRS-RVAIAGLGGVGGIHLMTLARTGIGNFNLADFDAYSPVNLNRQYGASIASF-- 383 Desulfovibrio vulgar...
1ZFN_A 82 -DRPKSQVSQQRLTQLNPDI--Q--LTALQQR-----LTGe-----------A---LKDAVA----RADVV-LDCTDN-- 130 Escherichia coli Q9UBE0 88 -GRNRAEASLERAQNLNPMV--D--VKVDTED-----IEKk----------pE-----SFFT----QFDAV-CLTCCS-- 135 human Q82IR6 181 -GERRNEAARRAVRSAAPERppRqeRASRRTT-----AGAa-----------DpglSLVILT----PRDGLgIHAPDP-- 237 Streptomyces avermit... O95352 409 gGKPKALAAADRLQKIFPGV--N--ARGFNMSipmpgHPVnfssvtleqarrDveqLEQLIE----SHDVV-FLLMDT-- 477 human Q6CBC3 355 gGKPKAETAAEALKEIYPAV--K--TSGITLEvp--mIGHsttsssekrvhqQydeLVSLIK----SHDAV-FLLMDS-- 421 Yarrowia lipolytica ... P38756 126 -GKPKVQCLKEHLSKIAPWS--E--IKARAKA-----WTKe-----------N---SHDLIFadgeSPTFI-VDCLDN-- 178 Saccharomyces cerevi... O13861 178 -GTPKTLAIKKAIKKFAPWI--E--VDARNAL-----FNPd-----------S---ADDLLSg---NPDFV-IDAIDN-- 227 Schizosaccharomyces ... Q6C125 141 -GIPKVESVKQYFSGVVPWA--N--IEAVQDL-----WVPaklskseqeyteM---AERLIYvngdKPDWV-LDCIDN-- 204 Yarrowia lipolytica P95234 94 -GQAKAEVMRNIVHDINPEA--E--IRAFCEP-----IGKe-----------N---AATFLE----GADVL-VDGIDAfe 144 Mycobacterium tuberc... Q72WQ5 384 -GRGKLDVMTERALSVNPFL--D--IRSFPEG-----VAAe-----------T---IDAFLK----DVDLL-VDGIDFfa 434 Desulfovibrio vulgar...
1ZFN_A 131 MATRQEINAACVALNTPLITASAVGFGGQLMVL--T----PPwEQG------------------------------CYRC 174 Escherichia coli Q9UBE0 136 RDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANlgEhefvEE-KTK------------------------------VAKV 184 human Q82IR6 238 AAAEPLIT-----SGTPHLYAGVVEGTGVVGPF--Vl---PG-ESG------------------------------CAGC 276 Streptomyces avermit... O95352 478 RESRWLPAVIAASKRKLVINAAL-GFDTFVVMR--HglkkPK-QQGagdlcpnhpvasadllgsslfanipgyklgCYFC 553 human Q6CBC3 422 RESRWLPTVICAALKKKCITAAI-GFDSFVVMR--HgvegVN-DLG------------------------------CYFC 467 Yarrowia lipolytica ... P38756 179 LESKVDLLEYAHHNKIDVISSMGVATKSDPTRVsiNdismTE-FDP------------------------------ISRC 227 Saccharomyces cerevi... O13861 228 IQTKVDLLSYCYNHKLPVIASTGSACKSDPTRVniAdisaTS-EDP------------------------------LSRA 276 Schizosaccharomyces ... Q6C125 205 IDAKVDLLHFCKSRDIKVISSMGAGCKSDFTQVriAdisqTA-EDP------------------------------LSKA 253 Yarrowia lipolytica P95234 145 IDLRRLLYREAQQRGIYALGAGPLGFSTAWVVF--D-----P-KGM------------------------------TFDR 186 Mycobacterium tuberc... Q72WQ5 435 LDIRRRLFNRALELGIPVITAGPLGYSCALLVF--M-----P-GGM------------------------------NFDS 476 Desulfovibrio vulgar...
1ZFN_A 175 lwp------------------dnQEPERNCRT--AGV------------------------------------------- 191 Escherichia coli Q9UBE0 185 sqgvedgpdtkrakldssettmvKKKVVFCPV--KEAlevdwssekakaalkrttsdyfllqvllkfrtdkgrdpssdty 262 human Q82IR6 277 ldqgradrdrtwprlvaqwrsgrPRQVQACDV------------------------------------------------ 308 Streptomyces avermit... O95352 554 ndvvap-----------gdstrdRTLDQQCTV------------------------------------------------ 574 human Q6CBC3 468 ndvvap-----------tdsmndRTLDQQCTV------------------------------------------------ 488 Yarrowia lipolytica ... P38756 228 v---------------------rRKLRKRGIA--TGIsvvfsnemldprrddilspi----------------------- 261 Saccharomyces cerevi... O13861 277 t---------------------rRRLRLLGIM--EGIpvvfstekpdprkasllplseee-------------------- 313 Schizosaccharomyces ... Q6C125 254 t---------------------rVKLRKLGVY--EGIpvifstekpgeakllpledsefekk------------------ 292 Yarrowia lipolytica P95234 187 yfdl----------------sdaMNTVDKFVAfiAGIapsathrrsidl------------------------------- 219 Mycobacterium tuberc... Q72WQ5 477 yfgi----------------dddTPPMEGYLRfgMGLaprpahlgymdr------------------------------- 509 Desulfovibrio vulgar...
1ZFN_A 192 ------------------------------------VGPVVGVMGTLQALEAIKLLSGI---------------ETP--A 218 Escherichia coli Q9UBE0 263 eedselllqirndvldslgispdllpedfvrycfseMAPVCAVVGGILAQEIVKALSQR---------------DPPh-- 325 human Q82IR6 309 --------------------------------------ALATAVAGVAAGHALAFLDGE----------------LPssA 334 Streptomyces avermit... O95352 575 ------------------------------------SRPGLAVIAGALAVELMVSVLQHpeggyaiasssddrmNEPptS 618 human Q6CBC3 489 ------------------------------------TRPGIAPIVSGYGVEILQAMCQDep------------sAPHqlR 520 Yarrowia lipolytica ... P38756 262 ----------------dcehrainavrdealrhlpeLGTMPGIFGLSIATWILTKVSGYp-------------mKENevK 312 Saccharomyces cerevi... O13861 314 --------------fekgdvdelsalpefrarilpvIGPMPGIFGLTIATYVLTSIAKYp-------------mDPIstM 366 Schizosaccharomyces ... Q6C125 293 ------------neenettvgelsvlpqyrvrilpvLGSLPAIFGLSMATHVLTSIGDYa-------------sIPEyiV 347 Yarrowia lipolytica P95234 220 ------------------------syvdienrtgpsVGLACHLASGVVAAEVLKILLGH---------------GRVyaA 260 Mycobacterium tuberc... Q72WQ5 510 ------------------------rfvslhdrrgpsLDIACHLCAGMAATEAVRILLHR---------------RGIrpV 550 Desulfovibrio vulgar...
1ZFN_A 219 G----ELRLFDGKSSQ--WRSLAL-R-RASG------CPV 244 Escherichia coli Q9UBE0 326 ----nNFFFFDGMKGNgiVE-----------------CLG 344 human Q82IR6 335 G----ARWETSVPRLD--WHARPVwAhPACS------CGA 362 Streptomyces avermitilis O95352 619 L----GLVPHQIRGFLsrFDNVLPvSlAFDK------CTA 648 human Q6CBC3 521 G----FLHNFSTVKIT--GQRFKC-------------CSA 541 Yarrowia lipolytica CLIB122 P38756 313 N----RLKFYDSILETfqKQMARL----NENkersslLGL 344 Saccharomyces cerevisiae S288C O13861 367 T----RPRLYEEA-----VKRLHA-EaRKAGvnldktFNA 396 Schizosaccharomyces pombe 972h- Q6C125 348 TqsrhKPKAYDQIQQTlvGQLARE-SkRRTG------ENG 380 Yarrowia lipolytica P95234 261 P----YFHQFDAYRSIyvRKRLR--------------CGN 282 Mycobacterium tuberculosis Q72WQ5 551 P----YFRQFDPLTGRhvRGRLRK-GlRSPL------QRL 579 Desulfovibrio vulgaris str. Hildenborough
Jiyao W et al.(2023). "The conserved domain database in 2023.",