2LUL,2YS2,4Y94


Conserved Protein Domain Family
BTK

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pfam00779: BTK (This model is not part of the current CDD release)
BTK motif
Zinc-binding motif containing conserved cysteines and a histidine. Always found C-terminal to PH domains. The crystal structure shows this motif packs against the PH domain. The PH+Btk module pair has been called the Tec homology (TH) region.
Statistics
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PSSM-Id: 513741
Aligned: 55 rows
Threshold Bit Score: 40.6219
Created: 12-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2LUL_A       129 KYHPKFWTDGSYQCCRQTEKLAPGCEKYNL 158 human
XP_019477451 706 AYHPGVFRGDKWSCCHQKDRTEPGCGRTRH 735
XP_006641032 683 SYHPGIYKGDKWSCCHQKDKTAVGCDKTRH 712
NP_001092921 678 CFHPGIYKADRWSCCHQKEKSDPGCDKTRH 707
ELK06884     169 SYHPGVFRGDKWSCCHQKDKTDLGCDKTRS 198
XP_007259442 120 KYHKGFWMDGKFSCCGQTVKNAPGCIQWHK 149
XP_015219159 119 KYHSGFWADGKFLCCKQASKNAPGCTLWDS 148
OWR43174     134 RYHPAVWSARRWWCCDAERKTAPGCSLASL 163
EDW55936      98 RYHPGLWSGKKWSCCKGLSRSTFGCRAAAH 127
2YS2_A        14 KYHSGFFVDGKFLCCQQSCKAAPGCTLWEA 43  human
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