1WSP


Conserved Protein Domain Family
DIX

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pfam00778: DIX (This model is not part of the current CDD release)
DIX domain
The DIX domain is present in Dishevelled and axin. This domain is involved in homo- and hetero-oligomerisation. It is involved in the homo- oligomerisation of mouse axin. The axin DIX domain also interacts with the dishevelled DIX domain. The DIX domain has also been called the DAX domain.
Statistics
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PSSM-Id: 513740
Aligned: 39 rows
Threshold Bit Score: 84.5282
Created: 12-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1WSP_A         4 SIVVAYYF-CGEP---IPYRTl--vRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDcgvVFEEVREDEAIL-PVFEEKI 76  Norway rat
EFX61233     231 FTKVVYFT-ERTV---TPFLTviprRLGEISLRDFKTLFDRPGVYRFHFKAQDAEYg--fVKEEIADDNMIL-PGFDGKI 303
XP_005472231 552 STKILYFT-GKSP---TPSMInipkRLGEVTLKDVKAAVDREGNYRYHFKALDPEFg--tVKEEVFLDEAIV-PGWEGKI 624
Q8ILP0         4 PTVVFYHIiNDKEdknSQNVFyilkPIGSITLKDIKHEFPLMGTYHFRFKILHNNIP---AWVDVTDESSPV-PSLNSCI 79  Plasmodium falc...
Q22227        11 QIKVFYYL-DDET---TPYVSvieaREGVATLGNFKNSFTKR-GYKYYAKELDPDIqr-eVKVELTTDSDRLrKSQNGFY 84  Caenorhabditis ...
EFO91403      70 MTKVYCHI-DDET---DPYMLevhvPPDLITLGDLKRVLMRT-NFKYYRKALDPDSgy-eVKAEIRDDSQRLsPSSNNLF 143
1_pfamImport   1 ITKVYCHM-DNEE---VPYMVevhvPPDCITLRDVKRKLTRT-NYKFFCIALDPDSgl-eVKAEIRDDSNKLyPLKDGRF 74 
XP_045092342 105 MTKVFYHL-DNDP---VPYTIdvhvPPDCMTLRDVKRKLPRT-NYQYYCIALDPDSgk-eVRAEIRDDSQRLyPLRSGEF 178
Q7RCQ9         4 TTIVFYNIiNDKEdknSQNVFyiskPPNLITLKDISDGFPLPGTYHFRFKINHNNNT---VWVDITDSSSNI-PTFNSSI 79  Plasmodium yoel...
XP_004227212 395 VTRVLYFT-DRDM---TPCMTsiskRVGDITLGEFKTVIKKEGNYRFIFKALDPELg--tVKEEVFHDDDVI-PGWEGKI 467 vase tunicate
1WSP_A        77 IGKV 80  Norway rat
EFX61233     304 IAWV 307
XP_005472231 625 VAWV 628
Q8ILP0        80 YAKV 83  Plasmodium falciparum 3D7
Q22227        85 EIFL 88  Caenorhabditis elegans
EFO91403     144 ELFL 147
1_pfamImport  75 QLFL 78 
XP_045092342 179 RLYM 182
Q7RCQ9        80 CMKV 83  Plasmodium yoelii yoelii
XP_004227212 468 VAWV 471 vase tunicate
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