6JZB


Conserved Protein Domain Family
DnaJ_CXXCXGXG

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pfam00684: DnaJ_CXXCXGXG 
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DnaJ central domain
The central cysteine-rich (CR) domain of DnaJ proteins contains four repeats of the motif CXXCXGXG where X is any amino acid. The isolated cysteine rich domain folds in zinc dependent fashion. Each set of two repeats binds one unit of zinc. Although this domain has been implicated in substrate binding, no evidence of specific interaction between the isolated DNAJ cysteine rich domain and various hydrophobic peptides has been found.
Statistics
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PSSM-Id: 425819
Aligned: 1245 rows
Threshold Bit Score: 38.695
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6JZB_A       155 CRTCNGSGakPGTSP-----VtCGRCHGAGVi-NVDTQTPLGMM-RRQVTCDVCHGRGKEIKy--PCTTCHGTG 219
Q5CTW2       235 CDACNGAG-----IIkglklAkCSNCGGSGL-----NVYHNGPL-LIKSLCMKCSGTGYSNl--mLCIKCNGSG 295 Cryptosporidium parvum
XP_001609996 307 CPDCNSSKsaQQKYI-----SrCNKCSGRGM--ITKNQRTPFGYiSTSRTCMQCQGRGMARi--qDCTTCNNSG 371 Babesia bovis T2Bo
Q4N5K9       270 CNFCNYND-----DSmnefiDqCNVCKGQGMe-TKEKRTKNGFF-RSSRTCTKCRGTGYQRl--kDCNKCDNTG 334 Theileria parva
Q2GI75       150 CSSCSGSGseGSAKS-----VqCSTCHGVGNv-RTQQ----GFF-TIERTCHVCNGEGEIIQn--KCKKCSGSG 210 Ehrlichia chaffeensis...
B9KH92       148 CSSCSGIGseGAVNS-----VkCGNCNGAGSv-RTRK----GFL-TIEEVCNVCNGEGEVIKn--KCRRCGGSG 208 Anaplasma marginale s...
Q2GLU9       152 CSHCSGSGgeGTAKS-----VkCGTCNGAGRi-RTRK----GFL-TIEELCHTCSGEGEVVKn--KCKRCAGSG 212 Anaplasma phagocytoph...
XP_002975700 140 CEKCKGAGvpSGVKPq----T-CKSCRGAGRifMQK-----GFF-SVESSCTACGGSGQFVKe--HCKACQGSG 200 Selaginella moellendo...
Q22WR9       251 CEKCNGTKrapg-----skkKlCKTCKGTGS-----VQFQQGLY-VWEFKCEECNGQGQIVd--cPCKNCKASG 311 Tetrahymena thermophi...
Q8QNB4       156 CPKCVGEGgke------ineKpCVACAGKGF-----SVTSHGSVfRSSIRCQACDATGKLRKigdPCSACKSTG 218 Ectocarpus siliculosu...
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