7L0P,7EWP,2PBI


Conserved Protein Domain Family
G-gamma
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pfam00631: G-gamma (This model is not part of the current CDD release)
GGL domain
G-protein gamma like domains (GGL) are found in the gamma subunit of the heterotrimeric G protein complex and in regulators of G protein signaling (RGS) proteins. It is also found fused to an inactive Galpha in the Dictyostelium protein gbqA. G-gamma likely shares a common origin with the helical N-terminal unit of G-beta. All organisms that posses a G-beta possess a G-gamma.
Links
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Statistics
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PSSM-Id: 513616
Aligned: 36 rows
Threshold Bit Score: 34.2223
Created: 12-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7L0P_G        19 TEKDKLKMEV-DQLKKEVTL-ERMLVSKCCEEVRDYVEerSGEDPLVKGI------P-EDKNPFKELkGGCVIS 83  human
Q9P2W3         4 WDVPQMKKEV-ESLKYQLAF-QREMASKTIPELLKWIEdgIPKDPFLNPD------L-MKNNPWVEK-GKCTIL 67  human
Q8T3F0       202 QNAQGYRCLM-DRLRFAIKTkPWLKALKASDTMVTWVDqrAEFDPFLHPPq----pS----NPWISDeASFWNQ 266 Caenorhabditis elegans
NP_001256419 332 QVQDTLKLEI-VQLNSRLSK-NVLRTSKVVENYLAYYEqrRVFDPLLTPPgsqadpFqSQPNPWINDtVDFWQH 403
Q5T3H5        84 PTEDELQQQI-KYWQIQLDR-HRLKMSKVADSLLSYTEqyLEYDPFLLPPd----pS----NPWLSDdTTFWEL 147 human
EDW56070     344 KTVDDMQRDV-DYLGKSLNR-TRMKMSQACESLVCYSEtfSEYDFFLQPAl----pS----NPWVTEdIAFWQL 407
KAI2584653   217 QTVVAVKKEI-MYYQQALMR-STVKSSVSLGGIVKYSEqfSSNDAIMSGCl----pS----NPWITDdTQFWDL 280
7EWP_C       253 pteDELQQQI-KYWQIQLDR-HRLKMSKVADSLLSYTEqyLEYDPFLl-------pP-DPSNPWLSDdTTFWEL 316 human
2PBI_A       219 QTVTAVRKEI-MYYQQALMR-STVKSSVSLGGIVKYSEqfSSNDAIMSGCl----pS----NPWITDdTQFWDL 282 house mouse
P63219         4 SSSVAAMKKVvQQLRLEAGL-NRVKVSQAAADLKQFCLqnAQHDPLLTGV------S-SSTNPFRPQ-KVCSFL 68  Norway rat
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