1X7A,8UF7


Conserved Protein Domain Family
Gla
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pfam00594: Gla (This model is not part of the current CDD release)
Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
This domain is responsible for the high-affinity binding of calcium ions. This domain contains post-translational modifications of many glutamate residues by Vitamin K-dependent carboxylation to form gamma-carboxyglutamate (Gla).
Links
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Statistics
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PSSM-Id: 513583
Aligned: 82 rows
Threshold Bit Score: 25.9626
Created: 12-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1X7A_L          6 LEEFVRGNLERECIEEKCSFEEAREVFENTEKTNEFWKQYV 46  pig
29_pfamImport   1 LEELKMGNLERECMEEKCSYEEAREVYEHDEATNEFWTNYN 41 
7_pfamImport    1 FEEMKKGNLERECWEETYYYYEIMHIYEHFLVNNEFWNKYK 41 
XP_005986997   44 FEEVKNGDLERECFEEVCSKEEAREVFEDTDATEKFWTRYL 84 
Q63772         50 FEEAKQGHLERECVEEVCSKEEAREVFENDPETDYFYPRYQ 90  Norway rat
XP_069035313    2 LEESKKGNLERECIEEVCDREEAREIFENDPETEYFIPRYV 42 
P53813         46 LEETKKGNLERECIEELCNKEEAREVFENNPETDYFYPKYL 86  Norway rat
8UF7_C          5 LEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYT 45  human
NP_001229297   57 FEEFKKGNLERECMEEICSYEEVREIFEDDEKTKEYWTKYK 97  house mouse
Q19AZ8         49 FEEMRKGNLERECVEEQCSREEAYEALESPSETDAFWAKYT 89  pig
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