Conserved Protein Domain Family
Gla
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pfam00594: Gla 
Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
This domain is responsible for the high-affinity binding of calcium ions. This domain contains post-translational modifications of many glutamate residues by Vitamin K-dependent carboxylation to form gamma-carboxyglutamate (Gla).
Links
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Statistics
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PSSM-Id: 425770
Aligned: 89 rows
Threshold Bit Score: 50.9835
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_018670146   30 FEEAQQGNIERECIEEVC-SWEEAREAFETDvAGLNQFWNQYT 71   vase tunicate
3_pfamImport    1 FEEMKKGNLERECWEETY-YYYEIMHIYEHF-LVNNEFWNKYK 41  
2_pfamImport    1 LEELKQGNIERECYEEPPgDKKEAREAFEMM-RRQMEFWKEYT 42  
XP_022263877   45 LEEMKKGNLERECMEETC-SFEEAREVFEDT-AKTMEFWNKYK 85   dog
XP_027310293  116 LEELKQGDIEHECREEIC-TYEEAREAFENE-EKTKEFWKVYK 156  mallard
XP_014346761   25 LEEIKQGNIERECWEEAC-SYEEAREAFENE-EKTMEFWNQYN 65   coelacanth
XP_007254941  527 FEEFKKGDMERECREERC-SYEEAREIFENN-EKTDEFWNVYY 567  Mexican tetra
XP_006639361   42 FEEFRQGNIERECHEERC-SYEEAREVFENT-ERTDEFWNVYF 82   spotted gar
XP_016154688   45 LEEVRKGNIERECNEERC-SKEEAREAFEDQ-EKTEEFWNIYV 85   Collared flycatcher
ABJ09591      230 FEEFQPGNIERECEEERC-SREEAREAFEDD-ALTTEYWTRYT 270  vase tunicate
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