4IS7,1OXJ,5J8Y,3TAD,3BS5,2KIV,4IS7,2KIV,3HIL,5ZRY,2QKQ,1SGG


Conserved Protein Domain Family
SAM_1
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pfam00536: SAM_1 
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SAM domain (Sterile alpha motif)
It has been suggested that SAM is an evolutionarily conserved protein binding domain that is involved in the regulation of numerous developmental processes in diverse eukaryotes. The SAM domain can potentially function as a protein interaction module through its ability to homo- and heterooligomerize with other SAM domains.
Links
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Statistics
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PSSM-Id: 425739
Aligned: 55 rows
Threshold Bit Score: 41.486
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4IS7_A   95 SY-IPTDLLEWLCALGLPQYHKQLvsSGYDSMGLVADLTWEELQE-IGVNKlGHQKKLMLGVKRLA 158  human
Q9QX74 1409 HLwTKPDVADWLESLNLGEHKETFm-DNEIDGSHLPNLQKEDLID-LGVTRvGHRMNIERALKQLL 1472 Norway rat
Q9WV48 2102 GFwTKFDVADWLEWLGLSEHRAQFl-DHEIDGSHLPALTKEDYVD-LGVTRvGHRMNIDRALKFFL 2165 Norway rat
O35711  637 DH---IWVTRWLDDIGLPQYKDQFh-ESRVDGRMLQYLTVNDLLF-LKVTSqLHHLSIKCAIHVLH 697  house mouse
Q86W92  720 DF---NWVTRWLDDIGLPQYKTQFd-EGRVDGRMLHYMTVDDLLS-LKVVSvLHHLSIKRAIQVLR 780  human
3TAD_B  122 DMnHEWIGNEWLPSLGLPQYRSYFm-ECLVDARMLDHLTKKDLRVhLKMVDsFHRTSLQYGIMCLK 186  human
Q9W263  657 QLgHTWVATEWLPDIGLPQYAEPFv-QSLVDARMLDTLSKKELEKfLGVTRkFHQASIVHGIHVLR 721  fruit fly
O35711  562 AQwSTERVCTWMEDFGLGQYVIFAr-QWVTSGHTLLTATPQDMEKeLGIKHpLHRKKLVLAVKAIN 626  house mouse
Q86W92  645 AKwTKEQVCNWLMEQGLGSYLNSGk-HWIASGQTLLQASQQDLEKeLGIKHsLHRKKLQLALQALG 709  human
Q94071  696 VDwRSEQLADWIAEIGYPQYMNEVs-RHVRSGRHFLNMSMNEYEGvLNIKNpVHRKRVAILLRRIE 760  Caenorhabditis elegans
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