3QHP,2IV7,5N7Z,5D00


Conserved Protein Domain Family
Glycos_transf_1
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pfam00534: Glycos_transf_1 
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Glycosyl transferases group 1
Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Links
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Statistics
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PSSM-Id: 425737
Aligned: 44 rows
Threshold Bit Score: 80.0108
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3QHP_A   1 TPFKIAMVGRYSNEKNQSVLIKAVALSKY-----KQDIVLLLKG-------KGPDEKKIKLLAQKLGVKAEFGFVNSNE- 67  Helicobacter pylori 2...
O67183 411 KEPFFLMVSTLEPRKGHFQVLKAFEILWKk----GINVNLVIVGk-----eGWKVRKLVKHIKKHRFLGKHLFWFGYVSd 481 Aquifex aeolicus
P72900 190 TQPYFLYVGARGTYKNFDQLLLAFQKVTAkp--kYADLLLCVVG--------SPFENQEKERLEFLGLSKNVVHYGRATd 259 Synechocystis sp. PCC...
P26470 192 DATVLLYAGRISPDKGILLLLQAFKQL-Rt---lRSNIKLVVVGdpyasrkGEKAEYQKKVLDAAKEIGTDCIMAGGQSp 267 Salmonella enterica s...
2IV7_A 195 QQNLLLQVGSDFGRKGVDRSIEALASLPEs---lRHNTLLFVVGq----------DKPRKFEALAEKLGVRSNVHFFSGr 261 Escherichia coli str....
Q9HUF6 195 DDLLLVQIGSGFKTKGLDRSLKALSALPKa---lRRRTRLIAIG--------QDDPKPFLLQIAALGLNDQVQILKGRSd 263 Pseudomonas aeruginosa
O34413 190 DKKVILFAGRLSPTKGPHLLIHSMRRI-Lq---qHPDAVLVIAGgkw-fsdDSENQYVTYLRTLALPYRDHIIFTKFIPa 264 Bacillus subtilis sub...
P46915 190 GKKIVLFVGRLSKVKGPHILLQALPDI-Ie---eHPDVMMVFIGskw-fgdNELNNYVKHLHTLGAMQKDHVTFIQFVKp 264 Bacillus subtilis sub...
P44806 246 EDEIILKSHRALLAKYPNLLLLLVPr--------HPERFNVVADl------LKKEKFQFIRRSTNELPNENTQVILGDSm 311 Haemophilus influenza...
P54166 195 KYNLSPNKKVLLIMAGAHGVLKNVKELCEnlvkdDQVQVVVVCG--------KNTALKESLSALEAENGDKLKVLGYVEr 266 Bacillus subtilis sub...

3QHP_A  68 --LLEILKTCTLYVHAANV-ESEAIACLEAISVGIVPVIANsPLSATRQFALDE---RSLFEPN-NAKDLSAKIDWWLEN 140 Helicobacter pylori 2...
O67183 482 elLKELYKRALALIAASED-EGFGLPIVEAFRNNTPVIARD-IKVFREIAGDNA----FFFENTkNPEVIANAIKTWLEL 555 Aquifex aeolicus
P72900 260 gqLAKLYNQSIAFVYPSLY-EGFGIPPLEAMACGTAVIGSN-VSSIPEVVGDAG----LLFDPK-SMDQLVDQLLYVLEN 332 Synechocystis sp. PCC...
P26470 268 dqMHNFYHIADLVIVPSQVeEAFCMVAVEAMAAGKAVLASK-KGGISEFVLDGIt--GYHLAEPmSSDSIINDINRALAD 344 Salmonella enterica s...
2IV7_A 262 ndVSELXAAADLLLHP-AYqEAAGIVLLEAITAGLPVLTTA-VCGYAHYIADANc--GTVIAEPfSQEQLNEVLRKALTQ 337 Escherichia coli str....
Q9HUF6 264 --IPRFLLGADLLIHPAYN-ENTGTVLLEALVSGLPVLVTD-VCGYAHYIAEADa--GRVLPSPfEQDSLNRLLAEMLED 337 Pseudomonas aeruginosa
O34413 265 ddIPNLFLMADVFVCSSQWnEPLARVNYEAMAAGTPLITTN-RGGNGEVVKHEVt--GLVIDSYnKPSSFAKAIDRAFTD 341 Bacillus subtilis sub...
P46915 265 kdIPRLYTMSDVFVCSSQWqEPLARVHYEAMAAGLPIITSN-RGGNPEVIEEGKn--GYIIHDFeNPKQYAERINDLLSS 341 Bacillus subtilis sub...
P44806 312 geLMLMYGISDIAFVGGSLvKHGGHNPLEPLAFKMPVITGKhTFNFPEIFRMLVevqGVLEVNS-TADALERAVEALLNS 390 Haemophilus influenza...
P54166 267 --IDELFRITDCMITK-----PGGITLTEATAIGVPVILYKpVPGQEKENANFFedrGAAIVVN-RHEEILESVTSLLAD 338 Bacillus subtilis sub...

3QHP_A 141 Kle----rERMQNEYAKSA 155 Helicobacter pylori 26695
O67183 556 YrkglhpkPANLKQYKYTW 574 Aquifex aeolicus
P72900 333 Pi-----kRDSLIQKGKKQ 346 Synechocystis sp. PCC 6803
P26470 345 k------eRHQIAEKAKSL 357 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
2IV7_A 338 Sp-----lRXAWAENARHY 351 Escherichia coli str. K-12 substr. W3110
Q9HUF6 338 Ap-----aRAAWSRNGlay 351 Pseudomonas aeruginosa
O34413 342 Qe-----lMNKMTKNARKH 355 Bacillus subtilis subsp. subtilis str. 168
P46915 342 Se-----kRERLGKYSRRE 355 Bacillus subtilis subsp. subtilis str. 168
P44806 391 Ke-----sRERLGNAGYEV 404 Haemophilus influenzae Rd KW20
P54166 339 Ed-----tLHRMKKNIKDL 352 Bacillus subtilis subsp. subtilis str. 168
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