4MWS_A         11 PG---LAKQ---PSF----RQYSGYL---------KGSgsKHLHYWFVES--QK--DPENSPVVLWLNGGPGCSSLDGLL 67   human
O60123         38 PVdyeG-------------RMHAGHLn-------qTDQldGDLFFWMFES--VK--PEYEHRSILWLNGGPGCSSEDGSL 93   Schizosacchar...
P09620         37 PGlseVPDPsniP------QMHAGHIplrsedadeQDSsdLEYFFWKFTN--NDsnGNVDRPLIIWLNGGPGCSSMDGAL 108  Saccharomyces...
C4QZV7         26 dylvldlpglshlsetqrpTMHAGLLpln---lsfVADddTEYFFWRFSK--QD---VDRADIVFWLNGGPGCSSMDGAL 97   Komagataella ...
O13849        578 PEslgIDTV----------KQYTGYLd-------vEd--dRHLFFWFFES--RN--DPENDPVVLWLNGGPGCSSLTGLF 634  Schizosacchar...
Q96VC4        137 PSslgIDPDv---------KQYTGYLd-------dN-EndKHLFYWFFES--RN--DPKNDPVVLWLNGGPGCSSLTGLF 195  Aspergillus n...
P52710        112 PEvlkVDFT----------KQYSGYLd-------vE-AddKHFFYWFFES--RN--DPQNDPIILWLNGGPGCSSLTGLF 169  Komagataella ...
P00729        116 PKilgIDPNv---------TQYTGYLd-------vE-DedKHFFFWTFES--RN--DPAKDPVILWLNGGPGCSSLTGLF 174  Saccharomyces...
XP_013936465  120 rvkktdpgalgldHT----RQYSGYLd-------vE-DedKHFFYWMFES--RN--DPVNDPVILWLNGGPGCSSLTGML 183 
1AC5_A         15 PG---LSEV---PDPsnipQMHAGHIplrsedadeQDSsdLEYFFWKFTNndSN--GNVDRPLIIWLNGGPGCSSMDGAL 86   brewer's yeast

4MWS_A         68 TEHGPFLVQpD-GVTLEYNPYSWNLIANVLYLESPAGVGFSYS-DDKFy--------ATNDTEVAQSNFEALQDFFRLFP 137  human
O60123         94 MEVGPFRLDd--NNTFQLNPGRWDELGNLLFVDQPLGTGYSYS-LAKDf--------QSNNEKMANDFSIFFEKFLEEFP 162  Schizosacchar...
P09620        109 VESGPFRVNs--DGKLYLNEGSWISKGDLLFIDQPTGTGFSVE-QNKDegkidknkfDEDLEDVTKHFMDFLENYFKIFP 185  Saccharomyces...
C4QZV7         98 MELGPFVINp--KQEVEYNEGTWVEAADVVFVDQPGGTGFSST-TNy----------LTELTEVADGFVTFLARYFHLFP 164  Komagataella ...
O13849        635 MELGPSSIN-IeTLKPEYNPHSWNSNASVIFLDQPINTGFSNG-DDSVl----------DTVTAGKDVYAFLNLFFAKFP 702  Schizosacchar...
Q96VC4        196 MELGPSSIDe--NIKPVYNPYAWNSNASVIFLDQPVNVGYSYS-GSTVs----------DTVAAGKDVYALLTLFFKQFP 262  Aspergillus n...
P52710        170 FELGSSRINe--NLKPIFNPYSWNGNASIIYLDQPVNVGFSYS-SSSVs----------NTVVAGEDVYAFLQLFFQHFP 236  Komagataella ...
P00729        175 FELGPSSIGp--DLKPIGNPYSWNSNATVIFLDQPVNVGFSYSgSSGVs----------NTVAAGKDVYNFLELFFDQFP 242  Saccharomyces...
XP_013936465  184 FELGSASIGp--DLKPINNPYSWNSNATVIFLDQPVNVGFSYS-SKSVs----------NTVAAGKDVYAFLELFYQQFP 250 
1AC5_A         87 VESGPFRVNsD-GK-LYLNEGSWISKGDLLFIDQPTGTGFSVE-QNKDegkidknkfDEDLEDVTKHFMDFLENYFKIFP 163  brewer's yeast

4MWS_A        138 EYKNN--KLFLTGESYAGIYIPTLAVLVMQDp----------------SMNLQGLAVGNGLSSYEQNDNSLVY-----FA 194  human
O60123        163 ERAND--EWFIAGESFAGQYIPHIAAKLKEKn----------------LVNLGGLAIGNGWINPLSHYETYLN-----YL 219  Schizosacchar...
P09620        186 EDLTR--KIILSGESYAGQYIPFFANAILNHnkfsk--------idgdTYDLKALLIGNGWIDPNTQSLSYLP-----FA 250  Saccharomyces...
C4QZV7        165 ADVYK--KFTLGGESYAGQYVPYILKAIMDDlksds-------gqlpkELYLKGALIGNGWIDPNEQSLSYLE-----FF 230  Komagataella ...
O13849        703 QYAHL--DFHIAGESYAGHYIPQFAKEIMEHnqganffvasgyemekqYINLKSVLIGNGLTDPLVQYYFYGKma--cES 778  Schizosacchar...
Q96VC4        263 EYAEQ--DFHIAGESYAGHYIPVFTSEILSHqk--------------rNINLKSVLIGNGLTDGLTQYEYYRPma-cgEG 325  Aspergillus n...
P52710        237 EYQTN--DFHIAGESYAGHYIPVFADEILSQkn--------------rNFNLTSVLIGNGLTDPLTQYRYYEPma-cgEG 299  Komagataella ...
P00729        243 EYVNKgqDFHIAGESYAGHYIPVFASEILSHkd--------------rNFNLTSVLIGNGLTDPLTQYNYYEPma-cgEG 307  Saccharomyces...
XP_013936465  251 HLLKN--DFHIAGESYGGHYIPVFASEILTHad--------------rSFNLTSVLIGNGLTDPLNQYPFYERmacstDG 314 
1AC5_A        164 EDLTR--KIILSGESYAGQYIPFFANAILNHnkfsk--------idgdTYDLKALLIGNGWIDPNTQSLSYLP-----FA 228  brewer's yeast

4MWS_A        195 YYHGLLG-NRLWSSLQTHCCsqNKCNFYDNKDLECVTNLQEVARIVg------------------------NS------- 242  human
O60123        220 VEKGMVDfESELG------------QYLHHSWAECLLAFDKIGSGSgdlskces---------flgdilymVSkep---- 274  Schizosacchar...
P09620        251 MEKKLID-ESNPNF-----------KHLTNAHENCQNLINSASTDEaahfsyqe----------cenilnlLLsytress 308  Saccharomyces...
C4QZV7        231 IKKELIDiHGSYM------------PGLLQQQEKCQNLINHSSGEAsesqisysacekilndalrftrdkkAPld----- 293  Komagataella ...
O13849        779 PYGPIMS-QEECDRITGAY------DTCAKLITGCYQTGFTPVCIGa------------------------SLycnnami 827  Schizosacchar...
Q96VC4        326 GYPAVLD-ESSCRSMDNAL------GRCQSMIESCYNSESAWVCVPa------------------------SIycnnall 374  Aspergillus n...
P52710        300 GAPSVLP-ADECENMLVTQ------DKCLSLIQACYDSQSAFTCAPa------------------------AIycnnaqm 348  Komagataella ...
P00729        308 GEPSVLP-SEECSAMEDSL------ERCLGLIESCYDSQSVWSCVPa------------------------TIycnnaql 356  Saccharomyces...
XP_013936465  315 GYEPTLD-ESECEGMLETL------PRCLSLIESCYSSQSVFSCVPa------------------------SIycnnaql 363 
1AC5_A        229 MEKKLID-ES---------N--PNFKHLTNAHENCQNLINSASTDE-------------------------AA------- 264  brewer's yeast

4MWS_A        243 ------GLNIY---NLY--------------APCAGGVPSHF-RSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIP-EQ 297  human
O60123        275 ---gkaCMNMY---DIS--------------LES-----------TYPTCGMDWPYDLSYLTEFLSTREAMTSLNVNlEK 323  Schizosacchar...
P09620        309 qkgtadCLNMY---NFN--------------LKD-----------SYPSCGMNWPKDISFVSKFFSTPGVIDSLHLDsDK 360  Saccharomyces...
C4QZV7        294 ----qqCINMY---DYT--------------LRD-----------TYPSCGMSWPPYLPDVTAFLQKKSVLEALHL--DS 339  Komagataella ...
O13849        828 gpftktGLNIY---DIR--------------EEC-------------RDQEHLCYPETGAIESYLNQEFVQEAL----GV 873  Schizosacchar...
Q96VC4        375 apyqrtGQNVY---DVR--------------GKC-------------EDESNLCYKGMGYVSEYLNKPEVRAAVG---AE 421  Aspergillus n...
P52710        349 gpyqrtGKNVY---DIR--------------KEC--------------DGGSLCYKDLEFIDTYLNQKFVQDALG---AE 394  Komagataella ...
P00729        357 apyqrtGRNVY---DIR--------------KDC--------------EGGNLCYPTLQDIDDYLNQDYVKEAVG---AE 402  Saccharomyces...
XP_013936465  364 gpfqktGRNVY---DVR--------------KMC---------------EGTLCYKDMEYIDQYLNQDFVKEKVG---AE 408 
1AC5_A        265 ------HFSYQeceNILnlllsytressqkgTADCLNMYNFNlKDSYPSCGMNWPKDISFVSKFFSTPGVIDSLHLDsDK 338  brewer's yeast

4MWS_A        298 LPQWDMCNFLVn---LQ-YRRLYRSMNSQYLKLLSSqkYQILLYNGDVDMACNFMGDEWFVDSLNQKmEVQRR------P 367  human
O60123        324 VHDWEECNDDVa---LQyAREGIESSSKLIQDLVST--VPILLFYGENDFLCNYLSGEKLTRSLEWNgAVGFQ------N 392  Schizosacchar...
P09620        361 IDHWKECTNSVg---TKlSNPISKPSIHLLPGLLESg-IEIVLFNGDKDLICNNKGVLDTIDNLKWGgIKGFS------D 430  Saccharomyces...
C4QZV7        340 SASWSECSARVg---SHlKNKISVPSVDILPDLLQE--IPIILFNGDHDIICNCIGTERMIDKLEFNgDQGFT------E 408  Komagataella ...
O13849        874 EYDYKGCNTEVnigfLFkGDWMRKTFRDDVTAILEAg-LPVLIYAGDADYICNYMGNEAWTDALEWAgQREFY------E 946  Schizosacchar...
Q96VC4        422 VDGYDSCNFDInrnfLFhGDWM-KPYHRLVPGILEQ--IPVLIYAGDADFICNWLGNKAWTEALEWPgHKEFA------A 492  Aspergillus n...
P52710        395 VDTYESCNFEInrnfLFaGDWM-KPYHEHVSSLLNKg-LPVLIYAGDKDFICNWLGNRAWTDVLPWVdADGFE------K 466  Komagataella ...
P00729        403 VDHYESCNFDInrnfLFaGDWM-KPYHTAVTDLLNQd-LPILVYAGDKDFICNWLGNKAWTDVLPWKyDEEFA------S 474  Saccharomyces...
XP_013936465  409 VDTYESCNFDVnrnfLFaGDWM-KPYHKNVINLLEQg-LPVLIYAGDKDFICNWLGNQAWSNELPWSgHDEFE------S 480 
1AC5_A        339 IDHWKECTNSVg---TKlSNPISKPSIHLLPGLLESg-IEIVLFNGDKDLICNNKGVLDTIDNLKWGgIKGFSddavsfD 414  brewer's yeast

4MWS_A        368 Wl--vKYGd----------SGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLN 418  human
O60123        393 Q----SAQpfy-----lpgYSDQPSGSYVSSRNLTFARIVEASHMVPYDHPNEMKTLITAFFN 446  Schizosaccharomyces pombe 972h-
P09620        431 D----AVSfdwihkskstdDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKS-----LVSRGIV 484  Saccharomyces cerevisiae S288C
C4QZV7        409 G----TEYip-------wfYNEVNVGKVISERNLTYVRVYNSSHMVPFDNTPVSRGLLDIYFD 460  Komagataella phaffii GS115
O13849        947 A----ELKpw--------sPNGKEAGRGKSFKNFGYLRLYEAGHMVPFNQPEASLEMLNSWID 997  Schizosaccharomyces pombe 972h-
Q96VC4        493 A----PMEdlki---vdneHTGKKIGQIKTHGNFTFMRLYGGGHMVPMDQPEASLEFFNRWLG 548  Aspergillus nidulans FGSC A4
P52710        467 A----EVQdw--------lVNGRKAGEFKNYSNFTYLRVYDAGHMAPYDQPENSHEMVNRWIS 517  Komagataella phaffii GS115
P00729        475 Q----KVRnwt------asITDEVAGEVKSYKHFTYLRVFNGGHMVPFDVPENALSMVNEWIH 527  Saccharomyces cerevisiae S288C
XP_013936465  481 A----ELYnl-------tlKDGTKVGEVKNAGKFTFARMFDGGHMVPYDQPESSLAMVNRWIA 532 
1AC5_A        415 WihksKSTd----------DSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVSRGIVdiysn 467  brewer's yeast