3U5N,3IU6


Conserved Protein Domain Family
Bromodomain

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pfam00439: Bromodomain 
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Bromodomain
Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.
Statistics
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PSSM-Id: 425683
Aligned: 43 rows
Threshold Bit Score: 48.4636
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3U5N_A        86 CERLL----L---YLYCHE--LSIEFQEP------VPASIPNYYK-------IIKKPMDLSTVKKKLqkkHSQHYQ---I 140  human
XP_001307998   6 YQKVF----EataEFLKDP--FHEIFHTMvf---lNDASLPEYSK-------YVSKPIALEVIKANL---ESKKYS---T 63  
EAY09117       9 LLQEM----D---TMMKDE--MYVPFNDF------LGYVSEEYHQ-------KIARPIDLNTVKANL---ENRQYH---R 60  
EDO18860      24 LEEEF----Pa--DFFEDD--PAKIYESYlgflqnNTVVDGNFIS---------NNQLKLTTINAKY---ENKEYNvdnG 83  
Q6CY60       209 LEAAS----N---NNLDDTlnICQPFLELv-----DKDEYPEYEE-------VIRLPNSLNLVKNNL---ELGYYH---K 263  Kluyveromyces ...
3IU6_A        16 FVSVM----S---HQDDEG--RXYSDSLAe-----IPAVDPNFPN---------KPPLTFDIIRKNV---ENNRYR---R 66   human
XP_011391866 278 YSAVLdcirN---HIDATGrrPAEHLEQCp-----DPEVDPDFYE-------KVEKPTSLSAISQRI---QEGEYP---K 336 
Q7SEY6        54 FLEMI----RrtkDKSGRT--VADCFEDLi-----PREGNEDYYR-------RIKLPISLKTIERKL---HNQDFA---N 109  Neurospora crassa
XP_001704393  25 IRTVL----R---DSMKPL--DSFTLF--------QNPVVVDYPDlkqqyeaVIEFPCSLSEIKQRLsnrSGNTYT---H 84  
Q54Y18       508 ESTPL----D---KWFKNI--PYEDF---------VDSFKLKYYS-------IITEPVSITSILNKL---KSGPNY---Q 556  Dictyostelium ...
3U5N_A       141 PDDFVADVRLIFKNCERFNE-MMKVVQV-YADT 171  human
XP_001307998  64 PAEWYNDINRMYQNAIEYHY-KSPVGTK-EIGI 94  
EAY09117      61 YIDWYHDMELVFKNTIEFYKnEQFSPYPpMATY 93  
EDO18860      84 FYKLYHDIKLVCTMLVHYYP-QGTRNYQ-IIDK 114 
Q6CY60       264 IYDFITDVNLTFQNALVFND-EDTTIYS-DALK 294  Kluyveromyces lactis
3IU6_A        67 LDLFQEHMFEVLERARRMNR-TDSEIYE-DAVE 97   human
XP_011391866 337 ATDFEMDMLQLFENARRLHP-IGTQMYG-DAVV 367 
Q7SEY6       110 LSELEGYFKRMVMNAKEYYN-KGSDIFE-DAER 140  Neurospora crassa
XP_001704393  85 IGDVFCDLCLTISNAMTFNK-SNTVILE-QVRI 115 
Q54Y18       557 LAEVLKDFKQMLINVTLYHK-EPNEYWW-ISHQ 587  Dictyostelium discoideum
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