1QU2_A 26 QIQEKWDAEDQ-YHKAleKNKG-NET--FILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPI 101 Staphylococcu... Q05873 20 DRYDFWLKGKF-FEAG--SDQT-KEP--YSVVIPPPNVTGRLHLGHAWDTTLQDIVTRMKRMQGYDVLWLPGMDHAGIAT 93 Bacillus subt... P28350 148 AWYQWWEKAGY-FKPEs-CRKPsAGK--FVIPLPPPNVTGALHCGHALANSLQDTLIRWYRMKGYETLWVPGCDHAGIST 223 Neurospora cr... P07806 156 SWYDWWIKTGV-FEPEftADGKvKPEgvFCIPAPPPNVTGALHIGHALTIAIQDSLIRYNRMKGKTVLFLPGFDHAGIAT 234 Saccharomyces... P07118 13 PLYEHWEKQGY-FKPN---GDEsQES--FCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIAT 86 Escherichia c... P43834 19 ALYQRWEESGY-FKPS---ENEnAPS--YCIAIPPPNVTGSLHMGHAFQQTLMDTLIRFNRMEGHNTLWQTGTDHAGIAT 92 Haemophilus i... P41252 17 KILEFWTEFNC-FQEClkQSKH-KPK--FTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPV 92 human XP_001023177 42 nILKFWDEINA-FKQQleKTKD-CPP--FTFYDGPPFATGLPHYGNLLAGTIKDVVCRYASQNGKYVERRFGWDCHGLPV 117 Q2FZ82 26 QIQEKWDAEDQ-YHKAleKNKG-NET--FILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPI 101 Staphylococcu... P41257 26 QRFKKWFEQNYaYEKMkeNRKNaKKS--FTLHDGPPYANGHIHIGHALNKILKETIIKTHYFKGESVRFTPGWDCHGLPI 103 Campylobacter... P00956 27 GMLARWTDDDL-YGIIraAKKG-KKT--FILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI 102 Escherichia c... P09436 16 KVLSLWDEIDA-FHTSleLTKD-KPE--FSFFDGPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPI 91 Saccharomyces...
1QU2_A 102 EQALTKK-----GVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLI 176 Staphylococcu... Q05873 94 QAKVEAKlr-eeGKSRYDLGREKFLEETWKWKEEYADFIRSQWAKLGLGLDYSRERFTLDEGLSKAVREVFVKLYEKGLI 172 Bacillus subt... P28350 224 QSVVEKMlwkkeKKIRQELGREKFTDLVWEWKGEYHQRINNAQKLMGGSMDWSREAFTMDKNLTAATMETFCRLHDEGLI 303 Neurospora cr... P07806 235 QSVVEKQiwakdRKTRHDYGREAFVGKVWEWKEEYHSRIKNQIQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVI 314 Saccharomyces... P07118 87 QMVVERKiaaeeGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLI 166 Escherichia c... P43834 93 QMVVERKiaaeeGKTRHDYGREAFINKIWDWKAYSGGTISQQMRRLGNSIDWERERFTMDDGLSNAVKEVFVRLHEEGLI 172 Haemophilus i... P41252 93 EYEIDKTlgirgPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLV 172 human XP_001023177 118 EYEIDKKlgitnRQEVLKMGVDKYNAECRSIVMRYAQEWRSIVNRFGRWVDFDNDYKTLDLKFMESVWWVFKQMFDKGLV 197 Q2FZ82 102 EQALTKKgv-----drKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLI 176 Staphylococcu... P41257 104 EQQVEVKlgekkK----SLSKKEIREFCRQHASEFVDIQREEFKDLGIIADWDKPYLTMKFEFEAAIYRTLCEIAKKGLL 179 Campylobacter... P00956 103 ELKVEQEygkpgE----KFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHL 178 Escherichia c... P09436 92 EHIIDKKlgitgKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYPSFMESTWWAFKQLHEKGQV 171 Saccharomyces...
1QU2_A 177 YKGKKPVYWSPSSESSLAEAEI--EYHDKR----------------SASIYVAFNV------KDDKgvvdaDa------- 225 Staphylococcu... Q05873 173 YRGEYIINWDPATKTALSDIEV--IYKDVQ----------------GAFYHMSYPL------ADGS-----G-------- 215 Bacillus subt... P28350 304 YRSNRLVNWCTHLNTALSGLEV--ETKEITgrtlldvpgydkkvefGVLTHFKYQI------DGSE-----E-------- 362 Neurospora cr... P07806 315 YRASRLVNWSVKLNTAISNLEV--ENKDVKsrtllsvpgydekvefGVLTSFAYPV------IGSD-----E-------- 373 Saccharomyces... P07118 167 YRGKRLVNWDPKLRTAISDLEV--ENRESK----------------GSMWHIRYPLadgaktADGK-----D-------- 215 Escherichia c... P43834 173 YRGKRLVNWDPKLHTAISDLEV--ENKESK----------------GSLWHFRYPLandaktADGK-----D-------- 221 Haemophilus i... P41252 173 YRGVKVMPFSTACNTPLSNFEShqNYKDVQ----------------DPSVFVTFPL------EEDE-----Tv------- 218 human XP_001023177 198 YRGCKVMPYSNGCATVLSNFETqqNYKEVD----------------DPSLFIAFKT------AEDP-----Kt------- 243 Q2FZ82 177 YKGKKPVYWSPSSESSLAEAEI--EYHDKR----------------SASIYVAFDV------KDDK-----Gvvd--ada 225 Staphylococcu... P41257 180 CERSKPVFWSWAAKSALAEAEV--EYQDKE----------------DYSIFVAFDL------DVKA-----Ceklgvska 230 Campylobacter... P00956 179 HKGAKPVHWCVDCRSALAEAEV--EYYDKT----------------SPSIDVAFQAvdqdalKAKF-----Avsnvngpi 235 Escherichia c... P09436 172 YRGFKVMPYSTGLTTPLSNFEAqqNYKDVN----------------DPAVTIGFNV------IGQE-----Kt------- 217 Saccharomyces...
1QU2_A 226 KFIIWTTTPWTIPSNVAITVHPElkygqynvngekyiiaealsdavaealdwdkasiklekEYTGKELEWVVAQHPF--- 302 Staphylococcu... Q05873 216 SIEIATTRPETMLGDTAVAVHPE--------------------------------------DERYKHLIGKTVILPI--- 254 Bacillus subt... P28350 363 TIEVATTRPETMLGDTGIAVNPE--------------------------------------DPRYTHLVGKFARHPF--- 401 Neurospora cr... P07806 374 KLIIATTRPETIFGDTAVAVHPD--------------------------------------DDRYKHLHGKFIQHPF--- 412 Saccharomyces... P07118 216 YLVVATTRPETLLGDTGVAVNPE--------------------------------------DPRYKDLIGKYVILPL--- 254 Escherichia c... P43834 222 YLVVATTRPETMLGDTAVAVHPE--------------------------------------DERYQSLIGKTVVLPL--- 260 Haemophilus i... P41252 219 SLVAWTTTPWTLPSNLAVCVNPEmqyvkikdvargrllilm--earlsalyklesdyeileRFPGAYLKGKKYRPLFdyf 296 human XP_001023177 244 KFIAWTTTPWTLPSNLALVINKDfdyvkvldaktqehyilae-crlpelykkdkdgykileKFKGSELVGREYEPLFpyf 322 Q2FZ82 226 KFIIWTTTPWTIPSNVAITVHPElkygqynvngekyiiaealsdavaealdwdkasiklekEYTGKELEYVVAQHPF--- 302 Staphylococcu... P41257 231 SAVIWTTTPWTLVANQAIALNPNenyvitkeglifasal------lksmvekgltsgeiqkELNAKEFEKLEAINPL--- 301 Campylobacter... P00956 236 SLVIWTTTPWTLPANRAISIAPDfdyalvqidgqavilakd--lvesvmqrigvtdytilgTVKGAELELLRFTHPF--- 310 Escherichia c... P09436 218 QLVAWTTTPWTLPSNLSLCVNADfeyvkiydetrdryfillesliktlykkpknekykiveKIKGSDLVGLKYEPLFpyf 297 Saccharomyces...
1QU2_A 303 ----LDRESLVING-DHVTTDAGTGCVHTAPGHGEDDYIVGQQYEL-----PVISPIDDKGVFTEEG------------- 359 Staphylococcu... Q05873 255 ----VNREIPIVGD-DYVDMEFGSGAVKITPAHDPNDFELGNRHNL-----ERILVMNEDGTMNENA------------- 311 Bacillus subt... P28350 402 ----VDRLLPIVTD-NYVDKEFGTGAVKLTPAHDFNDYQLGQRHNL-----EFINILNENGTLNDNA------------- 458 Neurospora cr... P07806 413 ----LPRKIPIITDkEAVDMEFGTGAVKITPAHDQNDYNTGKRHNL-----EFINILTDDGLLNEECg------------ 471 Saccharomyces... P07118 255 ----VNRRIPIVGD-EHADMEKGTGCVKITPAHDFNDYEVGKRHAL-----PMINILTFDGDIRESAqvfdtkgnesdvy 324 Escherichia c... P43834 261 ----ANREIPIIAD-EYVDREFGTGVVKITPAHDFNDYEVGKRHNL-----PMVNVLTLNANIRDEAeiigtdgkplagy 330 Haemophilus i... P41252 297 lkckENGAFTVLVD-NYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIirkdsLPVCPVDASGCFTTEV------------- 362 human XP_001023177 323 lsrkQDGCFRILAG-DFVTADAGTGIVHCAPGFGDDDYKVSVANNIik-pdDPPVPVDENGHFTNVV------------- 387 Q2FZ82 303 ----LDRESLVING-DHVTTDAGTGCVHTAPGHGEDDYIVGQKYEL-----PVISPIDDKGVFTEEG------------- 359 Staphylococcu... P41257 302 ----NGRKSVLIMG-EHVLMDGGSGLVHTAPGHGEDDYYACLKYGI-----EVLMPVDDSGCYDETLrakgll------- 364 Campylobacter... P00956 311 ----MGFDVPAILG-DHVTLDAGTGAVHTAPGHGPDDYVIGQKYGL-----ETANPVGPDGTYLPGTy------------ 368 Escherichia c... P09436 298 aeqfHETAFRVISD-DYVTSDSGTGIVHNAPAFGEEDNAACLKNGVisedsVLPNAIDDLGRFTKDV------------- 363 Saccharomyces...
1QU2_A 360 -----GQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISK-------VRQDILDAI 427 Staphylococcu... Q05873 312 -----LQYQGMDRFECRKKLVKDLQEAGVLFKIEDHMHSVGHSERSGAVVEPYLSTQWFVRMQP-------LADAAIELQ 379 Bacillus subt... P28350 459 -----GPFKGQKRFDARYTVVEELTKLGLFVKKEPNPMKIPLCEKSKDVIEPMMTEQWWVRMKE-------MGEAALQVV 526 Neurospora cr... P07806 472 -----PEWQGMKRFDARKKVIEQLKEKNLYVGQEDNEMTIPTCSRSGDIIEPLLKPQWWVSQSE-------MAKDAIKVV 539 Saccharomyces... P07118 325 sseipAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADV-------LAKPAVEAV 397 Escherichia c... P43834 331 eatipADYRGLERFAARKKIVADFEALGLLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKP-------LADVAIKAV 403 Haemophilus i... P41252 363 -----TDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVEN-------MVDQLLRNN 430 human XP_001023177 388 -----SDFAGVYIKEADKLIRKNLKERGLLLVDSSFKHNYPFCWRSDTPLIYKAVHCWFIKVTA-------LKDDLLANN 455 Q2FZ82 360 -----GQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISK-------VRQDILDAI 427 Staphylococcu... P41257 365 pshllEEFIGLHIFKANEKILELLGEK--LLHSSKFIHSYPFCWRTHKPVIYRATKQWFILMDEpklqgktLRECAKEQL 442 Campylobacter... P00956 369 -----PTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQk-----gLRAQSLKEI 438 Escherichia c... P09436 364 -----PDFEGVYVKDADKLIIKYLTNTGNLLLASQIRHSYPFCWRSDTPLLYRSVPAWFVRVKN-------IVPQMLDSV 431 Saccharomyces...
1QU2_A 428 E---NTNFKVNW-GKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAEN-GEIIMtketvn-hvadlFAEHGSNIWfereak 501 Staphylococcu... Q05873 380 KkeeKVNFVPDR-FEKTYLHWMENIRDWCISRQLWWGHRIPAWYHKEtGELYVg----------lEAPEDSENW------ 442 Bacillus subt... P28350 527 Ee-gKVKISPES-ATKSYKRWLADIQDWCISRQLWWGHRIPAYRVIFeGEEGQreneksewvvgrTQEEAQAKAeakfag 604 Neurospora cr... P07806 540 Rd-gQITITPKS-SEAEYFHWLGNIQDWCISRQLWWGHRCPVYFINIeGEEHDridgdy-wvagrSMEEAEKKAaakypn 616 Saccharomyces... P07118 398 En-gDIQFVPKQ-YENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEA-GNVYVg----------rNEDEVRKENnlga-- 462 Escherichia c... P43834 404 Ed-gEIQFVPKQ-YENLYFSWMRDIQDWCISRQLWWGHRIPAWYDAEgN-VYVa----------rNEEEVRSKYnlds-- 468 Haemophilus i... P41252 431 D---LCYWVPELvREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDfEEVVCigsv----aeleELSGAKISDlhresv 503 human XP_001023177 456 K---KAYWVPKFaQEGRFNNWLQNVSDWCFSRSRFWGNPIPIWVSEDfEEVVCigsve---elkkLTGATEITDlhkdfi 529 Q2FZ82 428 E---NTNFKVNW-GKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENgE-IIMtketvn-hvadlFAEHGSNIWfereak 501 Staphylococcu... P41257 443 L---KTTFYPQS-GVKRIGSMVENRPDWCISRQRDWGTPIAFFRDKNtKEVIFddelfd-fvaaiFEKHGADAWwefeik 517 Campylobacter... P00956 439 K---GVQWIPDW-GQARIESMVANRPDWCISRQRTWGVPMSLFVHKDtEELHPrtlelmeevakrVEVDGIQAWwdldak 514 Escherichia c... P09436 432 M---KSHWVPNTiKEKRFANWIANARDWNVSRNRYWGTPIPLWVSDDfEEVVCvgsik---eleeLTGVRNITDlhrdvi 505 Saccharomyces...
1QU2_A 502 dllpegfthpgspngtfTKETDIMDVWFDSGSSHRGVL----E-TRPELS--FPADMYLEGSDQYRGWFNSSITTSVATR 574 Staphylococcu... Q05873 443 -----------------EQDTDVLDTWFSSALWPFSTMgwpdV-TAEDFKryYPTDVLVTGYDIIFFWVSRMIFQGIEFT 504 Bacillus subt... P28350 605 ------------rkftlEQDPDCLDTWFSSGLWPMAILgwpnT-ENLDFKkfFPTSMLETGWDILFFWVSRMIMLSLKMT 671 Neurospora cr... P07806 617 ------------skftlEQDEDVLDTWFSSGLWPFSTLgwpeK--TKDMEtfYPFSMLETGWDILFFWVTRMILLGLKLT 682 Saccharomyces... P07118 463 -------------dvvlRQDEDVLDTWFSSALWTFSTLgwpeN--TDALRqfHPTSVMVSGFDIIFFWIARMIMMTMHFI 527 Escherichia c... P43834 469 -------------avelKQDEDVLDTWFSSGLWTFSTLgwpeQ--TKELKmfHPTDVLITGFDIIFFWVARMIMFTMHFV 533 Haemophilus i... P41252 504 dhlt---ipsrcgkgslHRISEVFDCWFESGSMPYAQVhypfE-NKREFEdaFPADFIAEGIDQTRGWFYTLLVLATALF 579 human XP_001023177 530 dhlt---ipsqkgkgvlRRIDEVFDCWFESGSMPYGQQhypfSmNEEEFSkrFPADFIGEGIDQTRGWFYTLNVISTALR 606 Q2FZ82 502 dllpegfthpgspngtfTKETDIMDVWFDSGSSHRGVLe-----TRPELS--FPADMYLEGSDQYRGWFNSSITTSVATR 574 Staphylococcu... P41257 518 dlip---tnskykaenlEKVYDILDVWFDSGSTFNAVLnsglY-DAGEKR----ASMYLEGSDQHRGWFQSSLLVGTAIN 589 Campylobacter... P00956 515 ei-------lgdeadqyVKVPDTLDVWFDSGSTHSSVVd---V--RPEFAg-HAADMYLEGSDQHRGWFMSSLMISTAMK 581 Escherichia c... P09436 506 dklt---ipskqgkgdlKRIEEVFDCWFESGSMPYASQhypfE-NTEKFDerVPANFISEGLDQTRGWFYTLAVLGTHLF 581 Saccharomyces...
1QU2_A 575 GVS------PYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVK------------------------------------- 611 Staphylococcu... Q05873 505 GER------PFKDVLIHGLIRDEQGRKMSKSLGNGVDPMDVID------------------------------------- 541 Bacillus subt... P28350 672 GEV------PFTEVYCHSLIRDSEGRKMSKSLGNVIDPLDIIRgieledlhakllvgnlkeeevaratkyqktafpggip 745 Neurospora cr... P07806 683 GSV------PFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITgiklddlhakllqgnldprevekakigqkesypngip 756 Saccharomyces... P07118 528 KDEngkpqvPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDgislpellekrtgnmmqpqladkirkrtekqfpngie 607 Escherichia c... P43834 534 KDEngkpqvPFKTVYVTGLIRDEQGQKMSKSKGNVLDPIDMIDgisledllekrtgnmmqpqlaekiakatrkefaegia 613 Haemophilus i... P41252 580 GQP------PFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQ------------------------------------- 616 human XP_001023177 607 NSN------PYKNLIVNGIVLAADGKKMSKSKKNYDDPLLIAS------------------------------------- 643 Q2FZ82 575 GVS------PYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVK------------------------------------- 611 Staphylococcu... P41257 590 ESA------PYESILTHGFTTDEKGQKMSKSKGNVIASEYVAK------------------------------------- 626 Campylobacter... P00956 582 GKA------PYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMN------------------------------------- 618 Escherichia c... P09436 582 GSV------PYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLN------------------------------------- 618 Saccharomyces...
1QU2_A 612 QKGADIARLWVS-STDYLADVRIS 634 Staphylococcus aureus Q05873 542 KYGADSLRYFLAtGSSPGQDLRFS 565 Bacillus subtilis subsp. subtilis str. 168 P28350 746 ECGADAMRFTLLsYTTGGGDINFD 769 Neurospora crassa OR74A P07806 757 QCGTDAMRFALCaYTTGGRDINLD 780 Saccharomyces cerevisiae S288C P07118 608 PHGTDALRFTLAaLASTGRDINWD 631 Escherichia coli K-12 P43834 614 AHGTDALRFTLAaLASNGRDINWD 637 Haemophilus influenzae Rd KW20 P41252 617 KYGADALRLYLI-NSPVVRAENLR 639 human XP_001023177 644 KYSVDAIRLYMI-NSPLVRAEEMS 666 Q2FZ82 612 QKGADIARLWVS-STDYLADVRIS 634 Staphylococcus aureus subsp. aureus NCTC 8325 P41257 627 TYGVEILRLWIL-LSDYSSDLKIS 649 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 P00956 619 KLGADILRLWVA-STDYTGEMAVS 641 Escherichia coli K-12 P09436 619 KYGADALRLYLI-NSPVLKAESLK 641 Saccharomyces cerevisiae S288C
Jiyao W et al.(2023). "The conserved domain database in 2023.",