7S05,4ZLP,7ABV,7ABV,2OO4,2OO4,1PB5


Conserved Protein Domain Family
Notch
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pfam00066: Notch (This model is not part of the current CDD release)
LNR domain
The LNR (Lin-12/Notch repeat) domain is found in three tandem copies in Notch related proteins. The structure of the domain has been determined by NMR and was shown to contain three disulphide bonds and coordinate a calcium ion. Three repeats are also found in the PAPP-A peptidase.
Links
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Statistics
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PSSM-Id: 513115
Aligned: 96 rows
Threshold Bit Score: 30.195
Created: 12-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7S05_B         406 PNC----AE-GCPGSWiKDGYCDKACNNSACDWDGGDCS 439  human
EGT55952       536 YRCpeniRQ-HCIDRR-GDGICDWECSFIGCGFDGGDCN 572 
XP_045093315   626 YHCpeyiRD-YCIKKR-GNGECDYACSFVGCGFDGGDCN 662 
20_pfamImport    2 EPCnp-iFEaYCSKHY-ADGKCDTWCNNVGCNWDGLDCE 38  
XP_002140175  3090 GYCs-----pSCFSQYvGDGMCDSHCFNESCNWDADDCR 3123
XP_064407862  1529 RTCnv-mYEqYCWHHY-NDGFCDLGCHFPQCAWDGQDCF 1565 coelacanth
XP_040062778  1529 QPCne-hYDtYCMSNY-GNGYCDYGCNNEECNWDGLDCE 1565 black-legged tick
P07207        1557 KSCds-lFDaYCQKHY-GDGFCDYGCNNAECSWDGLDCE 1593 fruit fly
XP_046462605  1543 QPCnp-iYDaYCQSHY-ANGRCDDGCNNAECNWDGLDCE 1579 common water flea
XP_020305236   662 EQCp---KNdYCTAHY-ADGQCDRECNVIGCGWDGGDCD 696  African eye worm
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