6I44,6I44,6I44,2F83,2F83,2F83,3HMT,4A5V,2LL3


Conserved Protein Domain Family
PAN_1
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pfam00024: PAN_1 (This model is not part of the current CDD release)
PAN domain
The PAN domain contains a conserved core of three disulphide bridges. In some members of the family there is an additional fourth disulphide bridge the links the N and C termini of the domain. The domain is found in diverse proteins, in some they mediate protein-protein interactions, in others they mediate protein-carbohydrate interactions.
Links
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Statistics
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PSSM-Id: 513075
Aligned: 93 rows
Threshold Bit Score: 35.217
Created: 12-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6I44_A 100 Ch------RDIYKGVDMRG---VNFNVS-KV----SSVEECQKRCT-NNIR---------CQFFSYATQtfhkaeyrnNC 155 human
Q22815  24 C-------FERYPNHRLVNv-rPYHSEW-RM----KTEDMCLLFCA-QSASr--------CRSVVYDTVq-------hIC 74  Caenorhabditis elegans
Q23328 212 Ckts-sgyYVVVGNEIVLPisgGDVQVYnEV-----EQGDCAKYCS-ENKGpdgs--tinCRSLNYFPVe-------kKC 275 Caenorhabditis elegans
Q21782  32 CplgehsrVQIIEGVEVSR---EATITF-QV----AILEQCVQACR-VSTYadgsrlpllCRSAHFNRAt-------rQC 95  Caenorhabditis elegans
Q9VCR4 241 Cs------YELYANSSFIY---AEARYL-GL-----SQKECQAMCS-HEAKf-------yCQGVSFYYVnql---slsEC 294 fruit fly
Q22815 399 Cs-----nFVAFRDYSVRI---EAVEEFnDLpkgyDGMQLCIELCV-LSTKf-------tCRSSTFNPIt-------gQC 455 Caenorhabditis elegans
O45277 420 C-------YRLYNNSIYNS---FDATIVgGL----QDLESCESECSwSHIRrr-----ekCLGVNWIPTt-------rGC 473 Caenorhabditis elegans
Q10952  49 Cpqg--lhADAIPEYVYFG---TMLATM-TV----DEHDQCLQKCA-EKPR---------CKAVNFFHPfayq--ekgFC 106 Caenorhabditis elegans
Q9VAG2 113 Cnpe-lvgFEIVTGYVFSApekLMDSQPgTL-----MLTDCLDTCR-KNKT---------CQSVNYETG---------LC 167 fruit fly
Q9V9X1 145 G-------FELITGYVLSAp-sKQLETLpGT----LMLTDCLEACQ-ANES---------CSAVNYETG---------LC 193 fruit fly

6I44_A 156 LLKYSPGg--TPTAIKVl--sNVESGFSL 180 human
Q22815  75 HYFSDEGv--dQAILSAk--mTYLRVVSQ 99  Caenorhabditis elegans
Q23328 276 ELYGILAephGSGKLLEn---EKVIYAEK 301 Caenorhabditis elegans
Q21782  96 SVYSDAIn--pNGYLEYkp-nQNVIYIEK 121 Caenorhabditis elegans
Q9VCR4 295 LLHSEDIvs-lGPRSLKl--rENSVYMRR 320 fruit fly
Q22815 456 RLMTEDSm--tSPDSFEydefQKALYFEN 482 Caenorhabditis elegans
O45277 474 MLFHKQId---fNVLQPs---FKAQFLAN 496 Caenorhabditis elegans
Q10952 107 ELLTEGQl--dNPSLMRp--fRKATYYEK 131 Caenorhabditis elegans
Q9VAG2 168 VLFSAHAdq-lPGALTKsq-fPVFTIYAQ 194 fruit fly
Q9V9X1 194 VMFRSTAdq-lPGSLSRsq-yPVFTVYAQ 220 fruit fly
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