8OSB,8OSJ,7XI3,1R05,7UX2,5I50,1AM9,2MH3,7F2F,1NLW,6OD3


Conserved Protein Domain Family
HLH
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pfam00010: HLH (This model is not part of the current CDD release)
Helix-loop-helix DNA-binding domain
Links
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Statistics
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PSSM-Id: 513062
Aligned: 143 rows
Threshold Bit Score: 41.2882
Created: 12-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8OSB_B          9 QRVMANVRERQRTQSLNEAFAALRKIIP-TLPSD-KLSKIQTLKLAARYIDFL 59   human
Q05195         57 SRSTHNEMEKNRRAHLRLCLEKLKGLVP-LGPESsRHTTLSLLTKAKLHIKKL 108  human
Q9NDP3         57 NRTSHNELEKNRRAHLRNCLDGLKAIVP-LNQDAtRHTTLGLLTQARALIENL 108  vase tunicate
P50539         68 NRSTHNELEKNRRAHLRLCLERLKVLIP-LGPDCtRHTTLGLLNKAKAHIKKL 119  human
Q99583        221 TREVHNKLEKNRRAHLKECFETLKRNIP--NVDDkKTSNLSVLRTALRYIQSL 271  human
NP_001162654  247 TREVHNKLEKERRAQLKECYDLLKKVLPmGDEDRkKTSNLTILDTAHKYVNSL 299 
Q19918         43 nQTRKSVSERKRRDEINELLENLKTIVQnPSDSNeKISHETILFRVFERVSGV 95   Caenorhabditis elegans
Q18053         15 sHGHRSETEKQRRDDTNDLLNEFKKIVQ--KSESeKLSKEEVLFRIVKLLSGI 65   Caenorhabditis elegans
Q8IWI9       2424 YRRTHTANERRRRGEMRDLFEKLKITLG--LLHSsKVSKSLILTRAFSEIQGL 2474 human
1NLW_A          1 sRSTHNEMEKNRRAHLRLSLEKLKGLVP-LGPDSsRHTTLSLLTKAKLHIKKL 52   human
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