Conserved Protein Domain Family

cl41769: toxin_MLD_like Superfamily 
membrane localization domain (MLD) of Vibrio MARTX, Pasteurella PMT, clostridial glycosylating cytotoxins, toxin effectors BteA (Bordetella T3SS effector A) and related proteins
This family includes membrane localization domains (MLDs) for toxin effectors such as the Rho-inactivation domain of Vibrio MARTX, Pasteurella mitogenic toxin (PMT), where it has been termed PMT C1 domain, and clostridial glycosylating cytotoxins including Clostridium difficile toxins A (TcdA) and B (TcdB), Clostridium novyi alpha-toxin (TcnA), and Clostridium sordellii lethal toxin (TcsL). It also includes the MLD located in the N-terminal minimal membrane-binding fragment of BteA, a type III secretion system (T3SS) effector protein from Bordetella pertussis, the causative agent of whooping cough.
Accession: cl41769
PSSM Id: 425400
Name: toxin_MLD_like
Created: 24-Nov-2020
Updated: 24-Nov-2020
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