Conserved Protein Domain Family

cl41753: SUN_cc1 Superfamily 
coiled-coil domain 1 of SUN domain-containing proteins
SUN (Sad1 and UNC-84) proteins (SUN1 and SUN2) are components of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex which is involved in the connection between the nuclear lamina and the cytoskeleton. Besides the core SUN domain, SUN proteins contain two coiled-coil domains (CC1 and CC2), which act as intrinsic dynamic regulators controlling the activity of the SUN domain. The model corresponds to CC1 that functions as an activation segment to release CC2-mediated inhibition of the SUN domain.
Accession: cl41753
PSSM Id: 425384
Name: SUN_cc1
Created: 24-Nov-2020
Updated: 24-Nov-2020
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