Conserved Protein Domain Family

cl41740: CC1_SLMAP-like Superfamily 
first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein and similar proteins
The family includes Sarcolemmal membrane-associated protein (SLMAP), its paralog TRAF3-interacting JNK-activating modulator (T3JAM), and similar proteins. SLMAP, also called Sarcolemmal membrane-associated protein, is a cardiac tail-anchored membrane protein that may play a role during myoblast fusion. T3JAM, also called TRAF3-interacting protein 3 (TRAF3IP3), is a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK. It may function as an adapter molecule that regulates TRAF3-mediated JNK activation. SLMAP contains an N-terminal FHA domain, followed by four coiled-coil (CC) domains and a transmembrane domain. The model corresponds to the first CC (CC1) domain that is responsible for the binding of suppressor of IKBKE 1 (SIKE1).
Accession: cl41740
PSSM Id: 425371
Name: CC1_SLMAP-like
Created: 24-Nov-2020
Updated: 24-Nov-2020
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