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Lanthionine-containing peptide SapB precursor RamS This entry represents a member of a biosynthetic gene cluster (BGC). The BGC (BGC0000551) is described by MIBiG as an example of the following biosynthetic class, RiPP (ribosomally synthesized and post- translationally modified peptide). This family includes RamS, the precursor of lanthionine-containing peptide SapB (also known as ProSapB). SapB, which does not appear to exhibit antibiotic activity, is formed from RamS through proteolytic cleavage and subsequent creation of lanthionine bridges. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",