Conserved Protein Domain Family

cl23853: Condensation Superfamily 
Click on image for an interactive view with Cn3D
Condensation domain
This domain is found in many multi-domain enzymes which synthesize peptide antibiotics. This domain catalyzes a condensation reaction to form peptide bonds in non- ribosomal peptide biosynthesis. It is usually found to the carboxy side of a phosphopantetheine binding domain (pfam00550). It has been shown that mutations in the HHXXXDG motif abolish activity suggesting this is part of the active site.
Accession: cl23853
PSSM Id: 420054
Name: Condensation
Created: 2-Feb-2016
Updated: 24-Nov-2020
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap