Conserved Protein Domain Family

cl19731: SipA Superfamily 
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Salmonella invasion protein A
Salmonella invasion protein A is an actin-binding protein that contributes to host cytoskeletal rearrangements by stimulating actin polymerization and counteracting F-actin destabilizing proteins. Members of this family possess an all-helical fold consisting of eight alpha-helices arranged so that six long, amphipathic helices form a compact fold that surrounds a final, predominantly hydrophobic helix in the middle of the molecule.
Accession: cl19731
PSSM Id: 418630
Name: SipA
Created: 16-Jan-2014
Updated: 24-Nov-2020
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