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Histone-like Protein p6 Family members such as protein p6 from Bacillus subtilis phage phi29 bind double-stranded DNA, forming a large nucleoprotein complex all along the viral genome, and have been proposed to be an architectural protein with a global role in genome organization. P6 is also involved in viral transcriptional control, repressing the C2 early promoter located at the right DNA end,and together with the viral regulatory protein p4, repressing early promoters A2b/A2c and activating late promoter A3.
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