Conserved Protein Domain Family

cl00188: BPI Superfamily 
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BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Taxonomy: root
PubMed: 16 links
Protein: Related Protein
Related Structure
Accession: cl00188
PSSM Id: 412206
Name: BPI
Created: 8-Feb-2008
Updated: 24-Nov-2020
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