Conserved Protein Domain Family
FAM221

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pfam14753: FAM221 
Protein FAM221A/B
This family of proteins is found in eukaryotes. Proteins in this family are typically between 99 and 305 amino acids in length.
Statistics
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PSSM-Id: 464299
Aligned: 16 rows
Threshold Bit Score: 256.901
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q22AF9        21 YQQLVGDyHNNG-QLMSEKEFEEFKKN-YREKAKNRIYCSWRNERGQDCKMVGPATKCFCDHR-FKDHEY---LDPKDKT 94  Tetrahymena the...
1_pfamImport   1 YKRIVGD-DDGG-QLFTPEEYEEYKKRmLPQRAKNRLYVSVGVPGGIDCKLVGPETPCFCSHRlYKQHRTdfeVVPCERP 78 
XP_003969318  20 YKRIVGD-DDGG-KLFTPEEYEAYKSKiVPQRAKNRLYVSFGVPGGIDCKLIGPETQCFCTHR-YKQHKVdfeEIPCERP 96 
ESO10554      24 YKLIVGD-DDGG-KTFTPEQYEEYKKRvLPQRMMNRLYTSWTNEDGMDCKLIGPETQCFCEHR-YRDHKTdfkEIPTDRP 100
XP_001635654  24 YKKIVGD-DDGG-KLFSPEEYEEYKKKvLPQRLKNRLFVSWTNPDGLDCKLVGPETPCFCEHRlYVQHKTdysSLPDTRP 101
XP_002126539  23 YRSIVGD-DDHG-RLFSPQEYEAYKKKvLPMRMKNRLYVSWSNPEGMDCKLVGPETLCFCQHR-YKQHVTdfkEKVKDSK 99 
XP_002110736  15 YTRIVGD-DDGG-KLFTPQEYEKYKKRvLPIRAKNRLYVSWTSPTGIDCKLIGPETPCFCTHR-YKQHKTdfeVIPSERP 91 
EEN43319      23 YRRIVGE-DDGG-QLFTPEQYEEYKKKvLPMRLKNRLYTSWSSPTGMDCKQIGPETPCFCGHR-YKQHKTdfqKLPEERP 99 
XP_021577918  20 YRRIVGE-DDGG-KLFTPEEYEEYKKKvLPMRLQNRLFVSWRSPTGMDCKLVGPETLCFCTHR-YKQHKTdfeTIPQQRP 96 
XP_031796464  74 YQKNAGE-DDGGcSLFTPEESDVFRNKiLPLRLRNRLYVSWRSPTGMDCKLVGPQTPCFCTHR-YKQHKTefiVLPADRP 151
Q22AF9        95 KV-HCKVPKCNCKCYYYIPAYGSYDFKCL-CKHSYRDHDNIK-KICNNk-CG---CSGFSSTWSCSCGSKFAGHTTVMET 167 Tetrahymena the...
1_pfamImport  79 LSlPCQVSGCHCSAYQYVPRIGTNPVRCR-CKHFPQDHSEAAgRLCKK--CDs--CTGFESPSTCGCGQPGFAHQTLVET 153
XP_003969318  97 LSlPCRVRGCRCSAYLYVPQIGSNHVRCK-CKHLPQDHGETAdHICKK--CGs--CRGFQSTMTCGCGQPSSAHQTLVET 171
ESO10554     101 IMlPCRAKNCRCASYHYIPRRGGSVVRCT-CKHQASQHSVLHpYKCKAasCSt--CQGFKSSYTCPCGQTYMQHKMIVET 177
XP_001635654 102 IPvPCKVAGCKCRHYNFVPKNGSQPIRCQ-CKHYTDDHSECSpHRCLKg-CK---CIAFKSSFTCGCGFPTHEHKTIVET 176
XP_002126539 100 -ElKCKIVGCGCSGYNYVPRNGTQPLRCH-CKHQATEHSEKSpFLCKNhkCG---CSGFRSSYRCGCGSLLEDHVTRVET 174
XP_002110736  92 IAmPCRAKGCLCKSYHYIPAMGSQHIKCSaCKHPSNEHSPKSpYKCARsnCGskqCQGFKTSYTCLCGELANKHQTIIET 171
EEN43319     100 INlPCRVNGCKCAAYHYVPLNGSQPIRCG-CKHYADNHSELFpYRCGAt-CT---CPGFKSSFTCGCGQATYRHETLVET 174
XP_021577918  97 IDlPCRVTGCQCRAYLFVPLNGTQPIRCR-CKHFADQHSPAPgFTCNA--CSk--CSGFHSSFTCACGQPAYAHDTVVET 171
XP_031796464 152 ISlPCKVSQCPCNSFHYVPLSGTRPIRCK-CKHYADQHSADSsRTCLA--CSk--CPEFRSYYTCSCGHPAHAHQTVVET 226
Q22AF9       168 REDRIRLGKPVDDmDrltdelnVP-VNMGGLTSFQQLVTGGDRyeqmIDKMGQNA 221 Tetrahymena thermophila SB210
1_pfamImport 154 KLERESRGRPTGR-D-------VPyAAMGGLTGFSSLLDGYLS----LEAGGSDQ 196
XP_003969318 172 KSEREARGRPVGR-D-------VPyAAMGGLTGFSSLCEGYLS----LETSNS-- 212
ESO10554     178 KDERIARGHPVGQ-E-------VPyQAMGGITGFSSLLDGYCR----LDPSGAGV 220
XP_001635654 177 KEERKSRGHPVGQ-D-------VPyAAMGGITGFSSLMEGYMR----LDDSGIGP 219
XP_002126539 175 RDERIKRGHPVANyE-------PPyAAMGGLTGLSSLIDGYMR----LDDSGIGA 218
XP_002110736 172 KEERENRGHPVSKdD-------VPyIAMGGLTGFSSLAEGYIR----CDPSGAGQ 215
EEN43319     175 KDEREARGHPVGC-D-------VPyAAMGGLTGFSSLADGYMR----LDPSGIGD 217
XP_021577918 172 KQERMAQGKPVGQ-D-------VPyAAMGGLTGFSSLAEGYMR----LDDSGIGA 214
XP_031796464 227 REERLALGKPVGR-N-------VPyAAMGEFAGFSALSEDFTD----LDENELEF 269
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