6S1M,6P1H


Conserved Protein Domain Family
zf-C4pol

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pfam14260: zf-C4pol 
C4-type zinc-finger of DNA polymerase delta
In fission yeast this zinc-finger domain appears is the region of Pol3 that binds directly to the B-subunit, Cdc1. Pol delta is a hetero-tetrameric enzyme comprising four evolutionarily well-conserved proteins: the catalytic subunit Pol3 and three smaller subunits Cdc1, Cdc27 and Cdm1.
Statistics
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PSSM-Id: 405022
View PSSM: pfam14260
Aligned: 229 rows
Threshold Bit Score: 33.5015
Threshold Setting Gi: 226520646
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6S1M_A       1012 CIGCRt-----------VLShQ----GAVCEFCQPRESEL--YQKEVSHLNALEERFSRLWTQCQRC-QGSLhe----dV 1069
Q4WWR3       1553 CIVCK------------SKL-Dhi-gIPVCSDCLQQPHIS--LLSLVSRQQQAEKRVSDLHRICQSCmGVPSgd----dV 1612 Aspergillus f...
EED46432     1327 CIVCK------------AKL-Ddt-dVPVCAECIRQPHIS--LLDLVTRQRHAEKSVSDLLRVCRSCmGVPFgd----eV 1386 Aspergillus f...
XP_662393    1578 CVVCK------------AKL-Yda-eIPVCSDCVRQPHVS--LLELVSRQRHAEQRVATLERICRSCmDVPFgd----eV 1637 Aspergillus n...
GAA85787     1572 CIVCK------------TKL-Rdt-dTPLCGNCSRQPHLA--MFELVSRQRAAEKRVVDLQRICRSCmGVTFgd----eV 1631 Aspergillus k...
XP_001949189 1396 CILCSkl--------sqH---------GFCEQC--QQNPQylIVQLNHLLSKWTKKQDDLETICRSCcgr------nfeL 1450 pea aphid
Q6CB61       1246 CIVCK-------------TA-QtsglSKLCATC--ESDPGhaTFVLNSDLRYREKRLDELNTICAQCsgd-------feT 1302 Yarrowia lipo...
XP_002171448 1364 CCLCLknpvtavpnaptS---------LLCEDC--RQHSDkaLMNTLYNLNSSSLLFNRLSHICEGC-SRISsv---dpI 1428 Schizosacchar...
XP_013021620 1390 CSSCLrnmvsnqnssenK---------YLCDDC--LRNIPaaTTRVIQQSKDVAVRLARLEDICRGC----ScisssdpV 1454 Schizosacchar...
CAZ85646     1521 CAVCG------------CKT-Srt-kNNICKDCTQNRDAS--IIHVRTQLARAEKRVLDLQTVCRSCeGSSPge----eV 1580 Perigord truffle
6S1M_A       1070 ICTSRDCPIFYMR 1082
Q4WWR3       1613 ICDSKDCPVFYSR 1625 Aspergillus fumigatus
EED46432     1387 KCDSKDCPVFYSR 1399 Aspergillus flavus NRRL3357
XP_662393    1638 KCDSLDCPVFYAR 1650 Aspergillus nidulans FGSC A4
GAA85787     1632 KCDSKDCPVFYSR 1644 Aspergillus kawachii IFO 4308
XP_001949189 1451 KCNSLNCQIYYga 1463 pea aphid
Q6CB61       1303 RCESQDCPIYYSR 1315 Yarrowia lipolytica
XP_002171448 1429 YCNSQNCCIYYER 1441 Schizosaccharomyces japonicus yFS275
XP_013021620 1455 LCRSKSCKIYYDR 1467 Schizosaccharomyces cryophilus OY26
CAZ85646     1581 ACTSQDCAVYYSR 1593 Perigord truffle
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