Conserved Protein Domain Family
zf-C4pol

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pfam14260: zf-C4pol 
C4-type zinc-finger of DNA polymerase delta
In fission yeast this zinc-finger domain appears is the region of Pol3 that binds directly to the B-subunit, Cdc1. Pol delta is a hetero-tetrameric enzyme comprising four evolutionarily well-conserved proteins: the catalytic subunit Pol3 and three smaller subunits Cdc1, Cdc27 and Cdm1.
Statistics
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PSSM-Id: 339136
View PSSM: pfam14260
Aligned: 260 rows
Threshold Bit Score: 31.9186
Threshold Setting Gi: 255086906
Created: 4-Apr-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P28340       1012 CIGCRtvlshqG----AVCEFCQ-PRESElYQKEVSHLNALEERFSRLWTQCQRC----QGSlhedVICTSRDCPIFYMR 1082 human
EFN82225       13 CVACG------EqtnkEVCAECVsQPSRT-ILVLLEKICQLERTHQQIASICHSCig-rSGD----IECASLDCPVLYQM 80   Jerdon's jump...
XP_019885602 2013 CITCG------EqtnkEVCPDCFsQPSRT-ILILLQKIRQIERNQQQITAICHSCtg-rIGD----VECLSLDCPILYRm 2080 Florida carpe...
XP_018317331 1872 CITCG------EqtnkEICPDCLlQPSRT-VLILLEKIKQLEKNHQQITAICHSCig-rLGD----IECVSLDCPVLYRm 1939 Trachymyrmex ...
XP_007259958 2960 CPVCD------EltqlGVCERCRaEPQRV-VVTLQQNLRQWESQQDQLLKICRACsgsvERQ----VPCVSLDCPVLYKV 3028 Mexican tetra
XP_003977815 2856 CPACD------EltqlGVCSHCRaEPQRV-AVTLHQEMRQWESQQELILQICRNCsgsaERL----VPCVSLDCPVLYKl 2924 torafugu
CAL49423      429 CPVCD------EltqhGICSKCRsQPQHV-VVILNQEIRELEYKQDQLAKLCRNCtgcsNQQ----IQCVSLNCPVLFKl 497  western clawe...
ETE72844     2965 CPVCD------EltqhGICNKCRsQPQHV-IVMLNQEIRELERKHEQITKVCKNCtscfDRQ----IPCISLNCPVFFKv 3033 king cobra
AAG09402     2964 CPVCD------DltqhGICSKCRsQPQHV-AVILNQEIRELERQQEQLVKICKNCtgcfDRH----IPCVSLNCPVLFKl 3032 human
XP_002604222  723 CPVCN------GpaqqGVCTHCQgDPQLV-AVTLNNQIRAWERTYQHLQQVCRSCtg-sPGQ----PSCISLDCPVLYKy 790  Florida lancelet
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