Conserved Protein Domain Family
DUF4258

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pfam14076: DUF4258 
Domain of unknown function (DUF4258)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 95 and 124 amino acids in length. Structural models show this family adopts a structure found in bacterial toxins, suggesting this family are the toxins in a toxin-antitoxin system.
Statistics
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PSSM-Id: 464082
Aligned: 111 rows
Threshold Bit Score: 34.9997
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Hoch_2128   14 FSTHALRRMSQRGIRRSQVMSAFLFGrahhlrgariyvigrrEVREAAEqdgfy-----------lddlEGL-------- 74 
jgi:Cylst_5292  23 FTAHAVTQSQHRCLVSEDIFYSVLKG----------------SVLEEQQdlnrapkfi---vsgrtefgMRL-------- 75 
WP_015236491    76 IKAHAQQHARAEGFLETDIVQVLDTGrvrav----------------------------------ypedHRWlvcgyfea 121 Deinococcus p...
Q9RXU2         144 vcPHAVQHARAEGFMESDIMDVLLTGrvrav----------------------------------ypedHRWlvcgyfea 189 Deinococcus r...
WP_013871032    53 YTTEAQDFLVNKSIDTTQINYILYKG----------------DINFSKSesrkkpcgi--yfvegeidnKET-------- 106 Lacinutrix sp...
WP_011963214    51 YSNVASKELAEDWLDTIDVKNTLQYG----------------DVDFSRSnlkiskgkly-tiigktiknQPI-------- 105 Flavobacteriu...
WP_002986154    51 YSSDAEFKLKEGWVVEDDIRKSLQYG----------------KVDFDQSnvdfekgkly-visgrnannDPI-------- 105 Myroides odor...
WP_014165299    52 YSKEASKILSEKWIDTTDIRNTLTYG----------------DVDFSRSniqtksggkryiiegfttkkQSI-------- 107 Flavobacteriu...
WP_015480232    50 YSNEAKKVMQTSDIDSLKIEKILNFG----------------DVDFGKGkprqkpcae--yfvtgkkelENV-------- 103 Polaribacter ...
Q8FSY0           5 ISPHARARMEQRGVTEQEIVETLSNPdltrpgnkpdrtiyerNi------------------------gKIV-------- 52  Corynebacteri...
jgi:Hoch_2128   75 -------HVVCHPDG-----LVLTVYR 89 
jgi:Cylst_5292  76 -------ETVWAYNErngwaTLISLfs 95 
WP_015236491   122 hgyilplHVVVELQEhgtwfDVVTAFV 148 Deinococcus peraridilitoris
Q9RXU2         190 hgirlplHVAVQHYRdg-hiDIVTAFV 215 Deinococcus radiodurans
WP_013871032   107 -------ALIIENCKek--aFIKTIkf 124 Lacinutrix sp. 5H-3-7-4
WP_011963214   106 -------EVIVENYEdk--vVLKEVkk 123 Flavobacterium psychrophilum
WP_002986154   106 -------TIKIVNYSdk--iKLlditk 123 Myroides odoratus
WP_014165299   108 -------ELEVENFEdk--sVLKNIIk 125 Flavobacterium columnare
WP_015480232   104 -------SLYISRCDst--sTIQKIMI 121 Polaribacter sp. MED152
Q8FSY0          53 -------CVVTVDQTnp--lVIVSAWK 70  Corynebacterium efficiens
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