Conserved Protein Domain Family
DUF4243

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pfam14027: DUF4243 
Protein of unknown function (DUF4243)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 348 and 477 amino acids in length.
Statistics
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Aligned: 217 rows
Threshold Bit Score: 78.8519
Threshold Setting Gi: 344035118
Created: 29-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KDE09872 122 FHNHAAHHLLASYSLGAPASLLKNIWE-VH-L----IEgtK---PMLPlhpigltEANWTKHLGNEKFYPNYLAFFMRQI 192 Microbotryum lychni...
CAP85952  63 FPNQLIHLLSSSFLQGADADTLGRIYEkEVsDlvkwKE--S---PAEIt------ILDWRGHLGCRKFDRAFVDFFEDEM 131 Penicillium rubens ...
EEA19078  62 SHNFIPQHLISAFLFGADGQTLESLYDlDSrIaeawKD--A---PGEVv------GSDWMDFLGKKEYERAFLDLFEDDL 130 Talaromyces marneff...
EED12307  64 SHNFLPQHLVSAFLFGADNYALDNLYEaNSgLlepwKD--A---PGEVv------GSDWMDFLGKREYERAFLDLFEDSL 132 Talaromyces stipita...
OBR16267  45 LHNHLPHALGSSYLLGATDVQLEAIYLsDSrTltaaNA--DklhREKIt------TENWRDFLGNKIYTVAYAQFFDSEV 116 Colletotrichum higg...
CCT74232  47 FHNHIPHALGSSYLLGASTAKLQEIYHaEEpNllavDA--Ev-vRYTIv------AENWRDHLGDKKYTAAYVDYFDDQI 117 Fusarium fujikuroi ...
EON61521  66 LHSHLPHLLGSAYGLGADSQQLIETYEhDVkTlvniDE--TfirGDKIs------EQDWRQFLGDKSYTVAYVDFFDEKV 137 Coniosporium apolli...
EHY52808  59 FHNHMPHILGSSYYLGGSSSKLLEILKaEGeHlr-pQE--TvppQNPIt------RENWRSFLASKDHTVEYARYFDDEI 129 Exophiala dermatiti...
Q2UH29     1 ----MPHMLGSAYLLGYPCEKLIEMYQnESpQlkslND--Gl-iRTGIt------KDNWRQFLGKKKYTAAYTTFFDQEL 67  Aspergillus oryzae
CBF83662  59 FHNHAPHSLCSFYLLGANADDLNRLYEaELkPleawID--S---PGEIs------TYDWRDYLGKREYQRAYVDFFEDEL 127 Aspergillus nidulan...
KDE09872 193 KE--I--PlatsqyaerkssviPVLERYLLGGQGQMLVRAVSGALHGLINIGYGVEFGLDALVAEGLAQSAVTS------ 262 Microbotryum lychni...
CAP85952 132 VRlsYdwK--------------EVVAEYLFTDKEPMFDSIMASLGLPLIHLAYAFEMDSREIGMEALALAATCHndiy-- 195 Penicillium rubens ...
EEA19078 131 VDqgYdwK--------------AVLQKFLFTGEQPLISSITAGLGQPLIHLALSLQMSVRDLAMEALTLAATSYydndvf 196 Talaromyces marneff...
EED12307 133 VEegYdwK--------------VVLQKYLFSAKQPLISSITAGLGRPLIHLALALQMSIKDIAMEALTLVATAYydndil 198 Talaromyces stipita...
OBR16267 117 EKrgGdwV--------------SVVEDYLFTGPRPVINGFIGGLGHSFIHLAYAFEFNDKEVATEALSLGCTEYdpth-- 180 Colletotrichum higg...
CCT74232 118 ERngGdwN--------------KVVLDHLFSGKEPLVNGFCGGLGHPYIHLAYGYEFNSKEVISEALSLGCTEYdpah-- 181 Fusarium fujikuroi ...
EON61521 138 RRrdGdwE--------------KVVQEYLYTGPEPLINGFCGGLAHPFIHLAYGYEFRIPEVVTEALSLGCTEYvvch-- 201 Coniosporium apolli...
EHY52808 130 AKtnGdwK--------------KVVTEHLYSGSKPLVNGFCGGLGHPFIHLAYAYEFDSKEVASEALSLGCTEVdfmh-- 193 Exophiala dermatiti...
Q2UH29    68 ANtqNdwK--------------ELVNEYLFTPPQPLINGFIGGLGHAFIHLAYAYEFSHPQIATEALSLGCTDRdpih-- 131 Aspergillus oryzae
CBF83662 128 VRhgYdwK--------------TVVFQYLFSGKEPLFNALASDLGHPLIHLAYAFEVSSREVAMEALSLATVCYgtah-- 191 Aspergillus nidulan...
KDE09872 263 ---PQVSplfdaawpppprtqtamqftlssalssfklgsgsfgtmpiaspsdsfvqtaarlPreRRVPREGL-AGFTILE 338 Microbotryum lychni...
CAP85952 196 kslGGPK------------------------------------------------------Hs-ENKESYESkSLFAILD 220 Penicillium rubens ...
EEA19078 197 kysDEPS------------------------------------------------------Yf-QAEPLYKScSISEILH 221 Talaromyces marneff...
EED12307 199 kysDDPS------------------------------------------------------Yf-QAEPIYKTpSVPEILG 223 Talaromyces stipita...
OBR16267 181 eflDSAP------------------------------------------------------Pd-N--STYKTpQLEQVLR 203 Colletotrichum higg...
CCT74232 182 kflDDAF------------------------------------------------------Pd-N--STYKTaSLEEMLI 204 Fusarium fujikuroi ...
EON61521 202 gllDNPP------------------------------------------------------Pi-P--SSYKTsDLAEVIK 224 Coniosporium apolli...
EHY52808 194 kyfDNPP------------------------------------------------------Ad-TGKSTYKTkDLLEILG 218 Exophiala dermatiti...
Q2UH29   132 hylDTPY------------------------------------------------------Pd-T--STYKTtSAKEILH 154 Aspergillus oryzae
CBF83662 192 kylDDPS------------------------------------------------------Ys-QAESSYHStSPFEILQ 216 Aspergillus nidulan...
KDE09872 339 RiLHDARLAPDv-------aVfekdfpklgnllkrraDIIIEWCDEWKFscdaspdygeehqakrkegtplktpnWeevV 411 Microbotryum lychni...
CAP85952 221 LvRKDEDLDGLfptp-gsdnLdtlf--------vsrnAALLNHWKAWKIe------------------------nP---I 264 Penicillium rubens ...
EEA19078 222 KvRTDERFNSYtitipgeqnMavif--------cdheAALLDHCNAWTIss-----------------------dP---T 267 Talaromyces marneff...
EED12307 224 KvRTDERFTNEalitpgehnMaiif--------rdheAALLDHCNAWMFps-----------------------dL---T 269 Talaromyces stipita...
OBR16267 204 KiRADDRFDGYanep-gfvnIltll--------ahheAQVLEHWNAWVVe------------------------dP---I 247 Colletotrichum higg...
CCT74232 205 NiHNDKRFDNYsddp-gfanVftll--------skyeSELLEHWNALVVe------------------------nT---T 248 Fusarium fujikuroi ...
EON61521 225 RvQRDDRFDGIvpmp-gtvnFgivl--------qnrfEAFMEHWNAWEVk------------------------dP---I 268 Coniosporium apolli...
EHY52808 219 RvVDDKRFDGLfehp-gfmnTfaih--------akaeDVLLEHYNAFVLd------------------------dV---E 262 Exophiala dermatiti...
Q2UH29   155 RvHTDIRFSSLfsvp-gfinIattf--------ahaeHALLEHWNAWDIv------------------------nP---A 198 Aspergillus oryzae
CBF83662 217 KvRADKRLSNLftap-gdhnTeivf--------rdaeATILDHWNAWKItsn---------------------sdP---V 263 Aspergillus nidulan...
KDE09872 412 EKCEELLWMATVLYA---SstrpgyACKP-KMDFFIMHGLTSVLFLPAILEVV-S---PHlrpyILHTHFRMIVSYWISR 483 Microbotryum lychni...
CAP85952 265 EQFRESQELAAALLVg-tAp-----DDSPgHYDWFFALNLATSHAVRVVLPFIpPqfqIS----LLRQWWLICVGIYVAQ 334 Penicillium rubens ...
EEA19078 268 TYFRESQKAAVALFTgakI------PAAGgKYNKSLLHPLLMSHAIHLILPHTpDkvhIS----LVQQWWLTTLAIYVAQ 337 Talaromyces marneff...
EED12307 270 THFRDSQKAIVSLFLgt--------sNSEnKYDKCLLYPLLMSHAIQVLFPHIpGkvhIS----LVQQWWLTTLAIYVAQ 337 Talaromyces stipita...
OBR16267 248 KQLGDFAHTAATLFMet--------cNAEgEYDFYLAHILTVAHALRVLFPHFsLerqVS----LMRQYGLYAVLVYLAQ 315 Colletotrichum higg...
CCT74232 249 IQFKDWLKTSAILSLst--------vDEEgNFDFFLAHVLTVGHALRILLPIMpEdrrLT----MMKQFGLFTTITYLMQ 316 Fusarium fujikuroi ...
EON61521 269 QQLEHCCDLSILLAIgs--------gYGDgKYDFFYAHIATVAHAIRVLYHYFpTdkrVS----IIRQYGFFTILIYILQ 336 Coniosporium apolli...
EHY52808 263 VQFEQIFDVAARIAVet--------gDAErQFDFFLIHILTAFHALRVILPYApVehrGN----MVKQFVMWTLLMYVAQ 330 Exophiala dermatiti...
Q2UH29   199 KQFRDVVDLAGLLLIgs--------rNGEgEYDFFLAHLLTVGHALRVLLPSFpWgyrVG----VLRQFWLFVLYVYVAQ 266 Aspergillus oryzae
CBF83662 264 KSFRESQELAVALLTatsSs-----DNRDaKYDFFFVHVLTTSHAVRVLLPLIpAkfqIP----LVRQWWLMTLAVYIGQ 334 Aspergillus nidulan...
KDE09872 484 GRPNLW----IKEtlmaaplypmppdasspstsavarylaslharkegelgpdgvpktpqvdangrlrleeelaeatetp 559 Microbotryum lychni...
CAP85952 335 LRPEIRid-qIRDyd----------------------------------------------------------------- 348 Penicillium rubens ...
EEA19078 338 LRPEIGfd-vIAAhd----------------------------------------------------------------- 351 Talaromyces marneff...
EED12307 338 LRPDIDfd-lIEGyd----------------------------------------------------------------- 351 Talaromyces stipita...
OBR16267 316 LRPETEwk-eSKAsg----------------------------------------------------------------- 329 Colletotrichum higg...
CCT74232 317 LRPSFGve-kMRPln----------------------------------------------------------------- 330 Fusarium fujikuroi ...
EON61521 337 KRLLFGie-eIESve----------------------------------------------------------------- 350 Coniosporium apolli...
EHY52808 331 LRRPVQtd-lVKKvd----------------------------------------------------------------- 344 Exophiala dermatiti...
Q2UH29   267 LRPGVGdgedVSGve----------------------------------------------------------------- 281 Aspergillus oryzae
CBF83662 335 LRPEINlh-sVRKyd----------------------------------------------------------------- 348 Aspergillus nidulan...
KDE09872 560 ldllGGGNPWSTVLAsa---vdHPDDHVAKVIRSL 591 Microbotryum lychnidis-dioicae p1A1 Lamole
CAP85952 349 ---lN-GKDWEWVAEnavngefSSNVQFVRTTRAL 379 Penicillium rubens Wisconsin 54-1255
EEA19078 352 ---tQ-GKNWGWIKQqalesqhATDAYFLQTLRVL 382 Talaromyces marneffei ATCC 18224
EED12307 352 ---mE-GKDWNWIRQqalkgphAMDAYFVSTLRVL 382 Talaromyces stipitatus ATCC 10500
OBR16267 330 ---dEVTPSWDKIYKsaldnkwFVDVHFPKVVRGL 361 Colletotrichum higginsianum IMI 349063
CCT74232 331 ---sD-NSSWESISKraleskwSTDMHWAKVIRAL 361 Fusarium fujikuroi IMI 58289
EON61521 351 ---tS-GRDWNWITEnalkhrwALDDHFFKVVRAT 381 Coniosporium apollinis CBS 100218
EHY52808 345 ---lK-GRGWDYVRDqalnsrfSLDSHYVKVVRAL 375 Exophiala dermatitidis NIH/UT8656
Q2UH29   282 ---lR-GRDWGWVYGrclegefWGDAHVVKVVRAF 312 Aspergillus oryzae
CBF83662 349 ---tE-GKGWGYMKDkalhgehSTETHYIKALRVI 379 Aspergillus nidulans FGSC A4
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