Conserved Protein Domain Family

pfam13917: zf-CCHC_3 
Zinc knuckle
The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.
PSSM-Id: 316439
View PSSM: pfam13917
Aligned: 21 rows
Threshold Bit Score: 40.0468
Threshold Setting Gi: 74840413
Created: 28-Jul-2016
Updated: 4-Aug-2016
Aligned Rows:
Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
Q7QJY9        11 ENVRAACKKCGFPGHLTYQCRnyltvdpqsqA--------Vvp---vqKRPGSESPEQNY 59  Anopheles gambiae str. PEST
Q4R5Z6        39 NKQHVRCQKCLEFGHWTYECT----------Gkr----kyL-------HRPSRTAELKKA 77  crab-eating macaque
A0E2U0        31 DAAAVRCQRCLKYGHLTYECK----------Nen----vyL-------YRPSRTMQFKEK 69  Paramecium tetraurelia
XP_001759262  94 FGGSQQCQKCFQMGHWTYECK----------Ndr----vyI-------SRPTRTQQLANP 132 Physcomitrella patens
XP_003058313  18 AGGRPQCQRCLKFGKWTFECCkd-------aSsr----vyV-------SRPSRTAQLKNP 59  Micromonas pusilla CCMP1545
XP_011010096  90 fGGNAQCQKCFQTGHWTYECK----------Ner----vyM-------SRPSRTQQLKNP 128 Populus euphratica
XP_002676901  17 EGGGGFCQKCFTEGHWTYQCK----------GekapsttyT-------KRLSHTEKLEMM 59  Naegleria gruberi strain NEG-M
KFG30589     236 AIYNIACQRCGGKGHMAHECYn--------tGgn----kyEmleeerpARPEHTAVIQPK 283 Toxoplasma gondii GAB2-2007-GAL-DOM2
XP_001696858  27 NRQQARCQRCLQIGHYTYECK----------Nea----ayA-------ARPSRTQQLKQG 65  Chlamydomonas reinhardtii
XP_001844226 102 FPKGVRCQKCLEFGHWSYECK----------Gkr----kyV-------HRSSRTQLLKKN 140 southern house mosquito
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap