Conserved Protein Domain Family

pfam13917: zf-CCHC_3 
Zinc knuckle
The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.
PSSM-Id: 372813
View PSSM: pfam13917
Aligned: 21 rows
Threshold Bit Score: 40.0473
Threshold Setting Gi: 74840413
Created: 1-May-2019
Updated: 18-Jul-2019
Aligned Rows:
Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
Q7QJY9    11 ENVRAACKKCGFPGHLTYQCRnyltvdpqsqA--------Vvp---vqKRPGSESPEQNY 59  Anopheles gambiae str. PEST
EER16637  11 AKEDILCQNCLQYGHWSYECK----------Npp----knA-------SRMSRMQKIRSK 49  Perkinsus marinus ATCC 50983
Q4R5Z6    39 NKQHVRCQKCLEFGHWTYECT----------Gkr----kyL-------HRPSRTAELKKA 77  crab-eating macaque
EDS36439 102 FPKGVRCQKCLEFGHWSYECK----------Gkr----kyV-------HRSSRTQLLKKN 140 southern house mosquito
EDP00550  27 NRQQARCQRCLQIGHYTYECK----------Nea----ayA-------ARPSRTQQLKQG 65  Chlamydomonas reinhardtii
ESS29615 236 AIYNIACQRCGGKGHMAHECYn--------tGgn----kyEmleeerpARPEHTAVIQPK 283 Toxoplasma gondii VEG
EFC44157  17 EGGGGFCQKCFTEGHWTYQCK----------GekapsttyT-------KRLSHTEKLEMM 59  Naegleria gruberi
EEY70243  44 SSVAAMCQKCLRRGHWTYECK----------Nga----vyV-------QRPSRSQQLRNP 82  Phytophthora infestans T30-4
EEH58264  18 AGGRPQCQRCLKFGKWTFECCkd-------aSsr----vyV-------SRPSRTAQLKNP 59  Micromonas pusilla CCMP1545
CBZ56078  12 gQAQAECQNCFQTGHWTYQCR----------Nek----vyL-------TRPTRTQMLRNP 50  Neospora caninum Liverpool
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