Conserved Protein Domain Family
RRM_5

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pfam13893: RRM_5 
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
The RRM motif is probably diagnostic of an RNA binding protein. RRMs are found in a variety of RNA binding proteins, including various hnRNP proteins, proteins implicated in regulation of alternative splicing, and protein components of snRNPs. The motif also appears in a few single stranded DNA binding proteins.
Statistics
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Aligned: 7 rows
Threshold Bit Score: 179.545
Threshold Setting Gi: 0
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEB18296             6 NFRHNPGFQGSPALLSTsg---alGVTTGPVMMVYGLDTKKLNCDKLFNLFCLYGNIARIKFLKTKEGAAMIQMGDGSAV 82   human bo...
FlyBase:CG9218-PB  148 PAGVVPGRNAPVAFTPQ-------GQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAV 220  fruit fly
4_pfamImport         1 DPLFIPSATLEVAATGWiaipglaGV-GNSVFLVSNFNLDRVTLQSLFILFSVYDNVQRVKILFNKKEYTLVQMANASQA 79  
OWK09974            97 GSRDTPELVAYPLPQASssy-mhgGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAV 175  Cervus e...
XP_021056983       271 PGALGPLTLTSSAVSGRmaipgasGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQA 350  shrew mouse
PDM64980          1532 GGNAPTDYYGYGADTGMv-----qPYKESGVVMVYGLEPGRFNCDMLFNMLCQYGNVNKVLFMRSKPDTAMVEMGSGREV 1606 Pristion...
TDH04581            75 SQRYGPSYGPPPPEYGP--------HADSPVLMVYGLEPSKVNADKVFNIFCLYGNVERIKFMKSKPGAAMVEMGDCYSV 146  yellow p...
EEB18296            83 ERCVQHLNNAPMfDSknRLQLGFSKQPFLSDvTNPFVLPDGSPSFKDFIRN 133  human body louse
FlyBase:CG9218-PB  221 ERCVQHLNNIPV-GTggKIQIAFSKQNFLSEvINPFLLPDHSPSFKEYTGS 270  fruit fly
4_pfamImport        80 QLDRSHMNGHKLhGK--PIGIILSKHQN----ALPHEGQKDEGLTKDYGNS 124 
OWK09974           176 ERAVTHLNNVKLfGK--RLNVCVSKQHSVVP-SQIFELEDGTSSYKDFAMS 223  Cervus elaphus hippelaphus
XP_021056983       351 QLAMNHLSGQRLyGK--VLRATLSKHQAV---QLPREGQEDQGLTKDFSNS 396  shrew mouse
PDM64980          1607 QTAIDHLYGTEIfGS--RLELKPSKQGEVAY-KEPFELADGSPSFRDYSSS 1654 Pristionchus pacificus
TDH04581           147 DRAITHLNNNFLfGQ--KLNVCVSKQQAIVP-GQCYQLEDNTSSFKDFHGS 194  yellow perch
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