2NUP,2DMW


Conserved Protein Domain Family
Longin

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pfam13774: Longin 
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Regulated-SNARE-like domain
Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain.
Statistics
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PSSM-Id: 338939
View PSSM: pfam13774
Aligned: 368 rows
Threshold Bit Score: 37.5473
Threshold Setting Gi: 122108798
Created: 30-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2NUP_C        40 QLFRKLneqsPTRCTLEa-GA-MTFHYIIEQ---GVCYLVLCEAAFPKKLAFAYLEDLHSEFDEQHgkKV--PTVSRPYS 112 human
Q3SEQ5        46 TCAARak--pGTRCAVT--NQeAHAVSYICIdknNLAALVIADDQYPEKVAFMVIQNMYQEYYRQYn-SMflDTI--VAD 118 Paramecium tetr...
Q8I346        45 TIPSRie--yNTKEIIT--HEnNTVFAFKYEd--NICPIVIATDDYPERVAFYMINEIYRDFISTIp-KEewSSV--KQD 115 Plasmodium falc...
Q23D12        33 EILPEIkp--etRDIYQtgDQkFFIRSTS-E---NFIFCILCSRDYQQRIGFTAIDQIMQIF------MEktTLEQRKTA 100 Tetrahymena the...
XP_001614643  45 TIPSRie--yNTKEIIT--HEsNTVFAIKFSd--NICPVVIATDDYPERVAFYMINEIYMDFIRTIp-KDvwSEV--KQD 115 Plasmodium viva...
KJE94083       7 TIGERta--pGTRNAVS--EQaYVFFCHAREd--GYTGIVIADSEYDKRVAFSVITKSLEQFTAKYt-KEtvD-R--ATA 76  Capsaspora owcz...
XP_001747534  46 TLAERtd--eGVRQSVQ--EKqYFCHVHNRQd--KLCGVVIVDEEYPARVAFSIISKALEEFKSKYp-VAswT----SNP 114 Monosiga brevic...
XP_007319995  47 TVVERtq--aTQRQSVQ--EGnYTAHVWNRGgpeNIAGIIITDHEYPVRPAFSLIAKLLDDFITKVp-QStyT-T--SAA 118 Serpula lacryma...
XP_008029990  46 EIAQRta--pNKQMDVL--EKgCMFHVYSHAd--PVCGFVVTDEEYPRLAAHRILRKVVDEFVSKYp-RSayD-GFTKES 117 Setosphaeria tu...
XP_007705962  46 vVAKRtp--pHKMTDVL--ENgHKFHALASAd--PICAVVVTDDEYPSSAAHRIVRKVLDEFSAKYp-RSayS-GFTADA 117 Bipolaris sorok...
2NUP_C       113 FI-E 115 human
Q3SEQ5       119 QNlN 122 Paramecium tetraurelia
Q8I346       116 NKiS 119 Plasmodium falciparum 3D7
Q23D12       101 LShS 104 Tetrahymena thermophila SB210
XP_001614643 116 NKvA 119 Plasmodium vivax Sal-1
KJE94083      77 RDlP 80  Capsaspora owczarzaki ATCC 30864
XP_001747534 115 RDmP 118 Monosiga brevicollis MX1
XP_007319995 119 PSiP 122 Serpula lacrymans var. lacrymans S7.9
XP_008029990 118 PKmS 121 Setosphaeria turcica Et28A
XP_007705962 118 TKlS 121 Bipolaris sorokiniana ND90Pr
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