Conserved Protein Domain Family
Asp_protease_2

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pfam13650: Asp_protease_2 
Aspartyl protease
This family consists of predicted aspartic proteases, typically from 180 to 230 amino acids in length, in MEROPS clan AA. This model describes the well-conserved 121-residue C-terminal region. The poorly conserved, variable length N-terminal region usually contains a predicted transmembrane helix.
Statistics
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Aligned: 147 rows
Threshold Bit Score: 39.974
Threshold Setting Gi: 74565628
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7MAZ2           54 V-PVTISG------KKYQFLLDTGASYTFIDNKLA----KTL---TQTTPESK-IpVTFhrMLS--DG-L-VTTSEKR-L 113  Photorhabdu...
EER08697         71 I-DFEINDc----qKPLRALLDSGAAMSVIHEAEL----TKIpdvVIQPTD-----LVV--RTA--DG-G-SPKVTGI-V 129  Perkinsus m...
Q09575          293 M-SVEVCG------KDVAFQLDTGSMITLISVKCW----EKL---GSPPLEK--VpHRI--SCA--NG-T-PMAVKGRcL 350  Caenorhabdi...
EEU39902        138 V-KAKVGK------HHVDALPDTGAQCNLISLQLA----EKA---GLVPRKGTeQaIRL--PTG--KQ-V-SSPGAVR-I 196  [Nectria] h...
Q0BX44          184 A-EVSVNG------VKGRALIDTGSPFSFMNTQMA----RAA---KAQQDDEKt--QML--QGA--TGgA-MAVSVAS-V 241  Hyphomonas ...
jgi:Bresu_0555  190 ArVGRVGD------LPFWIFVDSGAQHSVGNSALRtllsDSA---GPSVGPST-PvAIY--DTP--GL-T-RPATRAA-V 252  Brevundimon...
Q0UJH2          144 L-PLKFNGti--csATILACPDTGSDVNLISKDIA----KAL---GYEMRESA-ApGFYl-LLA--DG-TfVFPERYI-C 207  Parastagono...
wustl:cce_0938  100 V-KLKHNQi----eIQTTMLVDSGAEVSLISYKMG----QDL---GYQLADAE-StLVA--ETI--GG-N-VEYV-LR-N 158  Cyanothece ...
CAR64332        351 I-PYCYNG------TTVQALLDCGASSCFISRNLA----EKL---GLKMTPCKp--RQV--QSV--HS-M-ETTNYTV-E 407  Yarrowia li...
EDR06062        360 W-NCQINSltndfpVKTRALIDNGAHLVLIRPELV----ERL---GLKQYKLN-KpELV--DVAfsNG-KkKKTELYF-Y 426  Laccaria bi...
Q7MAZ2          114 HKadltlwqplaITLGN----HTVPSS--D-----PWIGIdmslfnqsIGQELDGILGIDT 163  Photorhabdus laumondii subsp. ...
EER08697        130 RN----------LKLTF----ADDTVVyeS-----FVVVD--------TPLSHAILLSTNA 163  Perkinsus marinus ATCC 50983
Q09575          351 VK----------FKLKG----IEYT----E-----YVYVR----------DRQTNLLGTSW 378  Caenorhabditis elegans
EEU39902        197 PF----------SFLGE----AKEYML--K-----CWIIP---------GCNRDLILSREF 227  [Nectria] haematococca mpVI 77...
Q0BX44          242 KR----------LSVAR----FSVRRL--N-----MIVADpamfddlgLSDEPAMLLGLDL 281  Hyphomonas neptunium ATCC 15444
jgi:Bresu_0555  253 EG----------LEIAG----QRMGAT--P-----LLFADlhvfdvldLATTPALLLGGDL 292  Brevundimonas subvibrioides AT...
Q0UJH2          208 AE----------FTFAV----QSSMGL--PhmsaiFYVLR---------HLPSQVIMGVSF 243  Parastagonospora nodorum SN15
wustl:cce_0938  159 VE----------FTIDN----HQLIAP--V-----AWLQT--------LTDTEQSLLGREV 190  Cyanothece sp. ATCC 51142
CAR64332        408 VP----------VELGK----WGC-DV--F-----AYVLP--------QMVGQELLLGMPF 438  Yarrowia lipolytica CLIB122
EDR06062        427 VK----------LALSSldsaWTSHVV--K-----ALVTP---------GLCLPIILGLPW 461  Laccaria bicolor S238N-H82
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