Conserved Protein Domain Family
AAA_26

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pfam13500: AAA_26 
AAA domain
This domain is found in a number of proteins involved in cofactor biosynthesis such as dethiobiotin synthase and cobyric acid synthase. This domain contains a P-loop motif.
Statistics
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Aligned: 41 rows
Threshold Bit Score: 121.583
Threshold Setting Gi: 288894582
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
18221:APL_0644      3 RTIILIPTTTGVGLTSVSLGLVHALeqkgsKVGFLKP-I-AQPIS--------G-EDTLDRSTS---IIRSAQ-T-TEVG 66  Actinobaci...
EEY53927           10 KAVYVAATRQHVGKTSTCLGLLQGLtarldRIGFLKP-V-GQESVaveggslrV-DKDVAVAKE---VFKLDTcN-YADM 82  Phytophtho...
WP_013304772        3 KAIYIATTEPNSGKSIISLGLMQMLlgkaaKVGYFRP-I-IDDYT--------N-GTKDNHIKTiisYFNLPI-A-YE-- 67  Maribacter...
OXE99781            3 KAIYIATSDYNSGKSIITLGLMSILigktaKVGYFRP-I-IEDFV--------D-GEVDNHIETvlsYFNLDI-D-FEDA 69  Flavobacte...
jgi:Cyan7425_4480   3 HSLYISTTEAGSGKALASLGIIDLIlrqttRVHFFRP-ViQTKNK--------R-DEDIELILT---YFGLNQ-T-YE-- 65  Cyanothece...
jgi:Namu_0579      12 RSLYIASPEALSGKSAVALGLVDLLsrrvgRVGVFRPiV-NADPQ--------R-DSVVELLIA---QPGIRQ-D-YDEA 76  Nakamurell...
jgi:Caci_6197       9 QGLYITATDAASGKTVVALGVAEAMsrrvrRLGVFRP-V-VPGGG--------AvDEVVELIRT---RYRIDE-P-YEDC 73  Catenulisp...
ADD07026           67 DTLLVASLEESTGKTAITMALARLAqsrgeQVGYMKP-K-GTRLQsnv--gktL-DEDPMLARE---LLDLDA-E-MHDL 136 Natrialba ...
jgi:Ferp_1982       2 RGILISSVEEKAGKTSLILALNEIFsg--yKTAYFKP-F-GTSPV--------R-EGEYLVDED---LKVVEG-NfSKSS 64  Ferroglobu...
BAI61189            2 RSIMISSPELYSGKSAVTMALAMKLkdndyKISYMKP-V-GNIIVdsn--gvlT-DDDALTMKR---VLGLDE-S-LQDL 71  Methanocel...
18221:APL_0644     67 EPFMLSEA----EA-LIGQNQ---SDVL--LEKVverhqQ-LSKNNEIVVVEGLIPTR-KN-SYAN-SVNYDIAQALDAE 132 Actinobaci...
EEY53927           83 SPVVIMPGyt-kRF-LDGHIT---VESQ--LDKIrtsfkR-ITEANEFTVVEGTGHTG-VG-SIVD-CNNARIAAELGVD 151 Phytophtho...
WP_013304772       68 DAFAFTRs---eVI-QMNNQN---KEDEv-LDKIiekykS-IEDQFDFVLVEGTDFSG-EGaIIEW-DINVLMAKNLGIP 136 Maribacter...
OXE99781           70 --YAITks---kLI-KKKNKGkigEVLDliIEKYk----K-LEERFDFVLVEGTSFTG-EG-TSIElDLNVLIAKNLGIP 136 Flavobacte...
jgi:Cyan7425_4480  66 ESFGLSSQev-nEL-LG-QHQ---ASIA--LEQIiakfkR-LEQRGDFILCEGSDYLG-EG-AAFEfNLNQEFARNLGCP 134 Cyanothece...
jgi:Namu_0579      77 VGVTYAQWha------dQDAA---LSRI--VDRFg----E-LSAEYDAVVVVGSDYTD-VT-TGNEwASNARIAANLGSP 138 Nakamurell...
jgi:Caci_6197      74 VGTTYDAV----HL-DPARAV---ETI---VDRYr----A-LAARCEAVVVVGSDYTDaAN-TAEF-GFNATVAANLGLP 135 Catenulisp...
ADD07026          137 EPVVYSPTfi-eQAiRSREDA---GELQ--NR-Ive-ayEgLAADCDRMFVEGGGRYD-VG-GIVD-LTDPDIAALLDAS 205 Natrialba ...
jgi:Ferp_1982      65 NPIVLDMPya-eFV-YSS------DSVE--LKKAiieayE--ELDADIVFVEGSSEYK-VG-KSLG-ISDDMVAEILDLK 129 Ferroglobu...
BAI61189           72 APILFTYRllddTL-EGKEKP---LAGK--LESTf---eK-ISKDKDIVVLEGAGDMS-GG-SVLG-LSDFEVARMTGSK 138 Methanocel...
18221:APL_0644    133 IILVAAP---GS-D-K----PTQLK----ERVEAAAsefggRH----NPNLLGVIINKF-NAPvdesgrtrpDlteifds 194 Actinobaci...
EEY53927          152 MVLVANG---GL-GsA----FDDLA----LNYSMCK-----TH----NVRVRGVILNKV-RED---------R------- 193 Phytophtho...
WP_013304772      137 TLILTSGvgkTLdE-L----VNNVY----LAYDSFK-----DH----GVEVLMVVANKV-QEK---------Nle----- 183 Maribacter...
OXE99781          137 TIIVGSG---VG-K-TleelLDSLY----LVYDSFK-----VK----EVEVLSVFANK--VQP---------E------- 180 Flavobacte...
jgi:Cyan7425_4480 135 ILILGRA---DN-R-T----PEATLrpiqMAVDAYR-----QH----NCQVMGIVLNR--ASP---------D------- 178 Cyanothece...
jgi:Namu_0579     139 VVLVVHG---RD-R-T----PAVIA----ATVELAR-----SElvawHAHPVAAIANR--VDP---------D------- 182 Nakamurell...
jgi:Caci_6197     136 VLLVVGG---ME-R-T----PQDVA----AVVRVSR-----QEltrlHATELAVIVNRVePGQe-------dA------- 183 Catenulisp...
ADD07026          206 VLLVAPY---ETpG-D----IDDVL----AAADAFG-----D-------RLVGVVFNNV-TDAa-------yDql----- 248 Natrialba ...
jgi:Ferp_1982     130 VLLVAKY---SN-DfV----IDRVL----TAKDVFK-----ER-------LRKVLINQL-TGY---------Ktsy---- 171 Ferroglobu...
BAI61189          139 ILLVARYc--DD-F-A----VNRIV----TYMK-LM-----PK----DVELVGIVFNN--IGPhfin--fvkE------- 185 Methanocel...
18221:APL_0644    195 fqhstqniaEVEALFAKSP---------I------KLL-ACVEWKSDLIATR 230 Actinobacillus pleuropneumoniae serova...
EEY53927          194 ----------VEMVREYFPkamkhwgsnV------PLI-GVVPNLPLLSNPS 228 Phytophthora infestans T30-4
WP_013304772      184 --------lVNESLQKVIP---------E------EVLvGSIPMNPVLGNPT 212 Maribacter sp. HTCC2170
OXE99781          181 ---------NIELVTKSLQ---------Ktlp-snVLI-NTIPLISSLNNPT 212 Flavobacterium johnsoniae UW101
jgi:Cyan7425_4480 179 ---------QVVTLKAALK---------TrygedgYLL-AVIPSDPRLGSPR 211 Cyanothece sp. PCC 7425
jgi:Namu_0579     183 ---------AVEDVRERLS---------Ra----gLVA-GALPNIPLLGAPT 211 Nakamurella multipartita DSM 44233
jgi:Caci_6197     184 ---------VRREVAAAFGsai---ddaT------PLV-CTIPEVPGLTAPT 216 Catenulispora acidiphila DSM 44928
ADD07026          249 -------etDVVPFLETSG---------V------TVF-GIVPSERSLSGVT 277 Natrialba magadii ATCC 43099
jgi:Ferp_1982     172 ------vsaVVGKVFAEND---------L------SVV-GVLPRDPLLAGMS 201 Ferroglobus placidus DSM 10642
BAI61189          186 ---------KVVPYFEKRN---------V------KVL-GVIPQNKTLMSVT 212 Methanocella paludicola SANAE
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