Conserved Protein Domain Family
Fer4_12

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pfam13353: Fer4_12 
4Fe-4S single cluster domain
This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.
Statistics
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PSSM-Id: 379137
View PSSM: pfam13353
Aligned: 82 rows
Threshold Bit Score: 87.2367
Threshold Setting Gi: 153805130
Created: 30-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
tigr:CHAB381_0327  11 IQGEGkfaGRL-----AVFfrFAGCNL--NCAG-FNCELK-----------------SPKtgeilrgcdtiravktahfd 65  Campylobac...
O25588             12 LQGEG---KRIgkpslFLR--LGGCNL--SCKG-FNCKTLlndeiltgcdslyavhpKFK-------------------- 63  Helicobact...
tigr:CFF8240_0222  11 VQGEGkfsGRY-----SLFirLGGCNL--SCKGfG-VKIK-----------------SPKtgeilvgcdt-ikavqtehf 64  Campylobac...
jgi:Tmel_0605      13 LDHPKh--FAL-----SIY--FQGCDRipKCPFcHNKETW-----------------EPF-------------------- 46  Thermosiph...
jgi:Paes_2284      83 EHRPL---IFY-----IVL--TYRCDL--ACDYcFQNSAK-----------------ALD-------------------- 113 Prosthecoc...
wustl:cce_2540     42 VNGPG---YRA-----VLW--VQGCLR--ECPGcFNPDSW-----------------SFE-------------------- 72  Cyanothece...
EAW45704           31 VNGPG---SRA-----VVW--VQGCPR--ECSGcFNPESW-----------------SFG-------------------- 61  Nodularia ...
jgi:Npun_F1624     31 VNGPG---CRA-----VVW--VQGCLR--ECPGcFNTNSW-----------------SFE-------------------- 61  Nostoc pun...
jgi:Aazo_0207      31 VNGPG---CRA-----VVW--VQGCPR--ECAGcFNPDSW-----------------TFE-------------------- 61  'Nostoc az...
jgi:Cyan7425_2045  31 VNGPG---CRA-----VIW--VQGCLR--ECPGcFNPASW-----------------VFE-------------------- 61  Cyanothece...
tigr:CHAB381_0327  66 YEKIS---Tv----SQLLDKIGTNF--K----NSLPIIVITGGEPLL--NYanPLFYEFIDEILKRNFe--VHFETNGTI 128 Campylobac...
O25588             64 TSWDYyneP-----KPLIERLEDLAp-N----YKDFDFILTGGEPSLyfNN--PILISVLEHFYRQKIp--LCVESNGSI 129 Helicobact...
tigr:CFF8240_0222  65 EHNKF---D-----FEALVNLVKET-------EFKPLIVITGGEPLLwyKD--EDLIKFIQWCFEQNYe--VHFETNGSI 125 Campylobac...
jgi:Tmel_0605      47 RGFEY---Nv----EKLIIRIKEKIn-DiidlHEKIAIVYLGGEPLApyNR--RALLEISKSLKEEFSekiINTLYTWRT 116 Thermosiph...
jgi:Paes_2284     114 GSIDT---ShlpalFNAMDEICERFp-Dt---RSRPVVALFGGEPLLrqHV--GLVEEIFREVAERGWvn-gPIISNGVS 183 Prosthecoc...
wustl:cce_2540     73 MNQLI---A-----VNT---LVEKIssH----PRNEGVTFSGGEPFW--QA--QALAELARKVKAKGL---NVMSFTGFT 130 Cyanothece...
EAW45704           62 INQLI---S-----VDTLAQNI--Ls-K----PNNTGVTFSGGEPFW--QA--TALASLARKLKAAGL---NIMSFTGFT 119 Nodularia ...
jgi:Npun_F1624     62 ANQLI---Av----DTLAENI---Ls-N----PRNMGVTFSGGEPFW--QA--TALASLARKVKAAGL---NIMSFSGFT 119 Nostoc pun...
jgi:Aazo_0207      62 INQLV---Ai----DSLGADILK----N----PHNTGVTFSGGEPFW--QA--SALANLARKVKVAGL---NVMAFTGFT 119 'Nostoc az...
jgi:Cyan7425_2045  62 ENQLV---Ai----ADLAAKI---La-N----PRNTGVTFSGGEPFW--QA--AALAELARTLKQAGL---NVMSFTGFR 119 Cyanothece...
tigr:CHAB381_0327 129 FVDFQKF-------PLYKNCVFAVSVKLGNSKEPR----E-KR-LNFTALQNLK 169 Campylobacter hominis ATCC BAA-381
O25588            130 FFEFS---------PILKELHFTLSVKLSFSLEEE----S-KR-IHLKALQNIL 168 Helicobacter pylori
tigr:CFF8240_0222 126 FVDFdk-------fKVYKKCKFAVSVKLAISGEPK----S-KR-INQKALQAIF 166 Campylobacter fetus subsp. fetus 82-40
jgi:Tmel_0605     117 LEDIKNQkl----sSFIEYIDEAILGPYDHDQRNTdkdgN-LL-FPASKNQKYI 164 Thermosipho melanesiensis BI429
jgi:Paes_2284     184 LDAHLPTfer--yrP--SGIQVTIDGPEEVHNQRR----H-TA-SYAGTFSSIV 227 Prosthecochloris aestuarii DSM 271
wustl:cce_2540    131 LEQLQSEdapagsqDLLAQLDILIDGPYIRSLAIN----SpDS-PVSSRNQRVH 179 Cyanothece sp. ATCC 51142
EAW45704          120 LKQLQSAsappdsaALLAELDILIDGPFVDSLAIN----SpTS-LVSSSNQGVN 168 Nodularia spumigena CCY9414
jgi:Npun_F1624    120 LKQLQSQsappgsqELLEQLDILIDGPFVQSLAIN----S-PNsPVSSSNQRVR 168 Nostoc punctiforme PCC 73102
jgi:Aazo_0207     120 LKQLQSEsappgseELLEQLDILIDGPFVESQAIN----SpLS-PVSSRNQQVH 168 'Nostoc azollae' 0708
jgi:Cyan7425_2045 120 LEELQSEtappgskALLEQLDILIDGPFVQSLAIN----DpTS-PVSSRNQRVH 168 Cyanothece sp. PCC 7425
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