Conserved Protein Domain Family
Y_phosphatase3

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pfam13350: Y_phosphatase3 
Tyrosine phosphatase family
This family is closely related to the pfam00102 and pfam00782 families.
Statistics
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PSSM-Id: 338693
View PSSM: pfam13350
Aligned: 258 rows
Threshold Bit Score: 96.5148
Threshold Setting Gi: 655123222
Created: 28-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6BSM6       336 IDGISNFRDIGAwkiqnptyrLPnyDNESHyyVKPHIAFRCANTADVTQ-M---GLKELRK-LNVKVMFDFRSSIEiNnd 410 Debaryomyces ha...
Q82PC9         7 FERLHNFRDLGG---------YTt-ADGRV--VRWGRLFRSDSLGKLTG-E---EWERFLA-LGIGTVIDLRYPWE---- 65  Streptomyces av...
WP_012850929  96 MEGLSNFRDLGG---------YRt-ADGGR--VRWGLVYRSDAPHLLTP-A---DLEVIAR-LGLRTAYDLRTDEE-R-- 155 Thermomonospora...
WP_012784277   7 FQRLHNFRDLGG---------YPa-GAGRA--TKWGVLYRSDNLRKLNEsD---DVERFRA-LDVHTVVDLRYPWE-I-- 67  Catenulispora a...
WP_013284511  11 FPALFNFRDVGG---------YAa-RDGRT--VRRGRLYRSDSLHRIDE-T---DRSAFTA-LGIRTVIDLRRPSE-V-- 70  Micromonospora ...
WP_013286435   7 FATLCNFRDLGG---------WRt-GDGRT--VARGRLYRSDSLAKLAG-E---DLERFAA-LGVRTVIDLRYPWE-I-- 66  Micromonospora ...
WP_015036266   7 FERLHNFRDLGG---------YPt-ADGGT--VRWETLYRSDSLAKLAD-AgptDLERFRS-LGVATVIDLRYPWE-I-- 69  Streptomyces ve...
WP_011905143  19 FDSLFNFRDVGG---------PAg-QDGRI--VRSGRLFRSDAPHRLAG-A---DRTAFAS-YGVRTVLDLRRPYE---- 77  Salinispora tro...
WP_013019385  19 FETIFNFRDLGG---------LAa-LGGSK--VRTGLVFRSDQFGNASS-E---DIDYIVDeLGVKTVVDLRRPTE---- 78  Stackebrandtia ...
ADB31388       6 WNGCLNARDVAG---------LPt-RYGGT--TRAG-IIRTDSLHQLDD-A---GWAAFHQ-VRAGLVLDLRSDWEmT-- 65  Kribbella flavi...
Q6BSM6       411 gSPqn--leK-----Yg-----iKRIHAPVf--SETDYSPEVI-AIRYTNLMTSW--FTYVNVYEDILENGTSAFRQVFE 473 Debaryomyces ha...
Q82PC9        66 -IDak--grV-----Pehp--afTYHNLSI--------EHRPYdQAGLGPDVETG--PFLAEKYMEVAHDGVKELRQVVE 125 Streptomyces av...
WP_012850929 156 -Ah------A-----PsvlpegvRREWIAIs--GAAAKTEQIV-QEVIAGQRTALpgDFLVRVYHAMAETEAAAFGRLLT 220 Thermomonospora...
WP_012784277  68 -EQsgrvpdF-----Pg-----lRYVNLSIe--HQ-----PYD-QGALGDDFDPW--RFLADRYMEVAQDGGKEIRGVLD 126 Catenulispora a...
WP_013284511  71 -ERdg---rV-----Pdyd--glTYRHIH------PEHADWGA-NRFDASGVSLA--RYLADRYADLARTGTAGLAEAVG 130 Micromonospora ...
WP_013286435  67 -ADrg---rA-----Pesl--gvTWHNLSIe--H-----RPYV-QADIDPDVDPW--RYLADRYAEVAEDGVAELRQAIE 125 Micromonospora ...
WP_015036266  70 -AAk-----GrlpetEd-----vSWHNLSVe--H-----RPYD-QEAIDPALDPW--RYLADRFAEVAEDGAVELRTALE 128 Streptomyces ve...
WP_011905143  78 -VDrd--grI-----Pefa--glTWRHIHP------EHAEWSA-TPYQA-GADLA--RYLADRYADMATTGTAGLAAAIG 137 Salinispora tro...
WP_013019385  79 -IAat--asF-----Pgdr--gvAVHNLEL-----GHIRWENI-ERDAGREPSPV--PFLVERYTAMVETGAITIRDTLN 140 Stackebrandtia ...
ADB31388      66 ---------E-----P-----------HPLdgdPAYRRIPWIDpVADQRRMPADE--PLMVDIYRGSLD---RNQGQILK 115 Kribbella flavi...
Q6BSM6       474 ---FIRD----EV-P--ASsfVFHCTAGKDRTGVLSMLILLFLGVDKHTISKEYELTTVGlknd------hasIrDKFIK 537 Debaryomyces ha...
Q82PC9       126 ---VIAAvatsTD-E--SV--VFHCASGKDRTGLVAALVLALLGVPESQIVEDFTLTELAterl------ladWrADHPG 191 Streptomyces av...
WP_012850929 221 ---GLAE----PG-Gl-PA--LIHCTAGKDRTGIGAALLLSALGVDERTVLDDYELSAVYysap-----qleqL-RTALA 283 Thermomonospora...
WP_012784277 127 ---VIAD----PEsG--TT--VFHCASGKDRTGIIAMLVLSLIGVSEDDVVADFALTELAterl------iadW-KAF-- 186 Catenulispora a...
WP_013284511 131 ---LIAD----SA-Na-PV--VVHCVAGKDRTGIVCALTLAVLGVPDEDVVADYALSTAAsrrf------tewV-RAT-- 190 Micromonospora ...
WP_013286435 126 ---VIAD----GE-H--PL--VFHCASGKDRTGLLAALVLSLLGVDEDQIAADFALTEQAtdrl------vaeW-RDRNG 186 Micromonospora ...
WP_015036266 129 ---VIAA----AD-G--PL--VFHCASGKDRTGLLAALVLALLGVPDEEILADFALTELAterl------iadW-R---A 186 Streptomyces ve...
WP_011905143 138 ---LIAD-----E-TnaPL--LVHCVAGKDRTGIVCGLTLAVLGVSDDDIATDYALSTAAgerf------rawFtATGRA 200 Salinispora tro...
WP_013019385 141 ---MMITa--------tPM--VFHCMAGKDRTGITAAVALKLLGVSDDDIAADYALTGEGmhry------ydwRaRIGKS 201 Stackebrandtia ...
ADB31388     116 ayrAIAEvpl-----dvPV--VVHCRSGKDRTGLLVALLQELAGVPGDVIAADYAMSETRlgipdriaalpgtDeERAA- 187 Kribbella flavi...
Q6BSM6       538 T--MENFKtkmenvedvaqiiaqgrkgwtieedGFQNLISSRYEAMLATIELFNQKYGSIVNYMKTQLKFEDSDLLKIYE 615 Debaryomyces ha...
Q82PC9       192 QepT------------------------------WPGYGRAPADVMRLFLDALTHQHGSMADYARDLLRIDEGLIAALRR 241 Streptomyces av...
WP_012850929 284 G--TGIDVe------------------------RFRAALDTSRQAMAAVLATLKERHGTIENYLLQEAGVSPDVLAELRA 337 Thermomonospora...
WP_012784277 187 ---YPDREl------------------------TWSAYARAPKEPMELFIADLKSRYGSVEGYAEQELGVDEALVAALKA 239 Catenulispora a...
WP_013284511 191 ---LPDAEe------------------------PPPPFLESPAEAMELFLAELRTGYGSVEGYLT-HAGVTEAQVESLRT 242 Micromonospora ...
WP_013286435 187 G-----ATp------------------------GWPAYGRAPAEIIRLVLAELRAAHGSVHGYVTDRLGVGAETIAALRA 237 Micromonospora ...
WP_015036266 187 A--HPGREp------------------------RWPGYGRAPADIMRLFLADLRARYGSVDAYVTGHVGLDPSVVTTLRS 240 Streptomyces ve...
WP_011905143 201 Vh-------------------------------pALPPLSCPEEAMLLFLAELRDRYGSVEGYLR-HAGVTDAQVAALRD 248 Salinispora tro...
WP_013019385 202 ----------------------------------PNEGLHPHAEAMYGLLRNIDNHFGSMEKYAR---AIDFQRTDELRA 244 Stackebrandtia ...
ADB31388     188 ----------------------------------AGLLWRSLPETILGALDHVDQRYGGVRAYL-ARCGLSAREIHRLGL 232 Kribbella flavi...
Q6BSM6       616 NLVY 619 Debaryomyces hansenii
Q82PC9       242 NLLE 245 Streptomyces avermitilis
WP_012850929 338 RLVq 341 Thermomonospora curvata
WP_012784277 240 KLVD 243 Catenulispora acidiphila
WP_013284511 243 HLLD 246 Micromonospora aurantiaca
WP_013286435 238 RLLT 241 Micromonospora aurantiaca
WP_015036266 241 RLVD 244 Streptomyces venezuelae
WP_011905143 249 HLLE 252 Salinispora tropica
WP_013019385 245 HLLT 248 Stackebrandtia nassauensis
ADB31388     233 RLLT 236 Kribbella flavida DSM 17836
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