Conserved Protein Domain Family
AAA_21

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pfam13304: AAA_21 
AAA domain, putative AbiEii toxin, Type IV TA system
Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Statistics
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Aligned: 79 rows
Threshold Bit Score: 35.1042
Threshold Setting Gi: 150013295
Created: 30-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Bind_0896     23 LTILVGLNGSGKSHLLQAIEIGaaetdlfpsLPGFHAGHPATippgSIVRIENSFITADIFSGAVLSSI-AGGHNPNHQL 101 Beijerincki...
eebua:HCDSEM_037  29 LSVVAGANGVGKTSFARAL------------AGDSRYSVIAG----FEWARWRRGPGAVLGVFLTFQAP-VEVPGVLYAH 91  Candidatus ...
jgi:Oter_3924     23 FNLVLGPNGSGKTSLIEALQHL------------------------------RTLSQLEPMDPITAHVT-EDGPSMVFQF 71  Opitutus te...
Q7NJA5            24 RVFVVGPNASGKSNFLDVFRFLrd------iAKPGGGLQKAVvargGVSKIRCLSARREPNIEIEIHISeSVNRSALWRY 97  Gloeobacter...
ADC91575          45 VSVLIGANNAGKSSVLQALDFLq--------DCVLHGVTSAAqmngRHGFFDLRTRGTDEPMSLRILFS-SAKTGIIYNY 115 Mageeibacil...
Q7UYP8            23 VTVLVGRSGTGKSNFVEAVRFLrdll-rgqpGGSGGGMGGVFgggqNPFALMRPLPMTEAPTRFEICFS-VRSSKERYRY 100 Pirellula sp.
jgi:Sros_7563     26 VNVLIGPNGAGKTNVLKVFRFLadm---irtDLIPAMDEHGGfdeiLFRGGESIPDHFRIKLKAAWTPHaTLEDSDEYEL 102 Streptospor...
Q7UEM4            23 LTVVTGPNGSGKTNLYRSLRLIas-----aaNGNLNQSLAEEggfeSVLWAGPESIPNEMKRGDVPVQGtLRRKPIALKL 97  Pirellula sp.
Q6AIC2            41 LNVVVGGNGAGKSNLISFFKM----------LRALIDGNLNRyvieHGGAGDLLFNGRKTTEKMEFETH-FNSRGYRFKL 109 Desulfotale...
Q8YSF6            25 LIVMIGANGAGKTSFLDVL------------STLAASANGKLqetlQSKGGLNEILTRGKAQELEIEVSmRVPQEQPLKY 92  Nostoc sp. ...
jgi:Bind_0896    102 NHRLLNFDIlrk-tvlADSLSNLENALGCPISSYLSSEEDPWQFGYDAILTKAGITVGSRKALEIKEAFDDAQSKLTIHL 180 Beijerincki...
eebua:HCDSEM_037  92 FLKLVACRA----------------------------------------------------------------------- 100 Candidatus ...
jgi:Oter_3924     72 TAPFERLQV---------RLACVDSNRCDAIHLTPPDAPDWPALKAEIERIRSFAFDPEAMASPTPLQPGAELAADGANL 142 Opitutus te...
Q7NJA5            98 EIGVKQETR----------GNRQPKLAYERVYKEDKLILDRPDEFDKNDDVRLTQTHLEQIVANLSFRDIAKFFESVLYL 167 Gloeobacter...
ADC91575         116 MLQIGDNDQ----------GKPLITAESLQIVEQEKGDFFRCADDKFTARFGTHEESQVVKPYDLPLLSVYAKLPGADFC 185 Mageeibacil...
Q7UYP8           101 LLDLGKSPE-------QGRFGEEKLLLGDTILYHQSSDKNAMAWIQEPRLVDIPKPGGIALGRMPSLSDVVVAYAALTEG 173 Pirellula sp.
jgi:Sros_7563    103 VVALNDPASqgqltrfERFKFPGPQGGNEILIRSDAVEVRAVSVRHTPSILDVLRSDAHMRTTGISSLSSGLSTLPRLSE 182 Streptospor...
Q7UEM4            98 AFSADPMSYci---dlGRPVPSNSMFDGDPEIKRECIWTGPTPDARSLCVDRKGANLRCRSGKGKWQDIDLHLSRGTSLM 174 Pirellula sp.
Q6AIC2           110 IPTPKDACS-------LEEEARYYESGLTGWWELGDSHDGTSRMVSEVTENRSDGQYSKPIYDAISSWQIYHFHDTGSRA 182 Desulfotale...
Q8YSF6            93 GLTLSPKGLsye--irNETLTQQRNPNKSEPFKYIESHGLDIKYFQEGSGLLRPNWEHNPLETSLSQVPKMYREPENLRK 170 Nostoc sp. ...
jgi:Bind_0896    181 TQPGHPLDADLHALrllvkdvaeilRISPLEVTKMQVLSRNCWGGFSIFEPQISLVIARYRDAMAQNDLytcadrrngts 260 Beijerincki...
eebua:HCDSEM_037 101 -------------------------GTAPSLACKLKLVLKLVGVSVRALNRPVNVGF----------------------- 132 Candidatus ...
jgi:Oter_3924    143 AAVLADWRETARAA-----------YDAFVAEALRLFPEYTKFELQSRPGHHVALAFTLLGEVGVVSGEd---------- 201 Opitutus te...
Q7NJA5           168 HLVPQLLRHPEAFSgpa------ipEDPFGRSFLERVAKTPEKTRRARLLKIEEALKFAVPQLKKLSDVrdelg------ 235 Gloeobacter...
ADC91575         186 REPYEYIEHWLYISfp-------alMNQPGRASRDFMLQASQLGNLSGGHRHINRYADNVPNVLAYLQKkhpniyq---- 254 Mageeibacil...
Q7UYP8           174 IGCYTFPNSVMLIGapa-----eagQSGFQDSGANYLDTMKKIVSNFQDASARQRIVKSLQRVNEGVSSvelndl----- 243 Pirellula sp.
jgi:Sros_7563    183 EAGAREVRALASRLg----------EFRVFDVSVDAARRPSRLLQRGGDSLEDDAANLAAFLLTLRKEDsdawsrleeda 252 Streptospor...
Q7UEM4           175 TEYADPFAAPEIIVmke-----qlrGWRFYDTFRCDSHAPARLPSPQTFTPVMANDGSNLAAALQTIREigdshiveqai 249 Pirellula sp.
Q6AIC2           183 GMRHYEIIQDNKSLr----------ADASNIGPFLLKLKKKHPQEYKDILNAIRLVTPFFEDFLLEPREsgnk------- 245 Desulfotale...
Q8YSF6           171 SLASCTYYGALDVSek-------spIRLPQPMRPAKLPGASGEDLVSCLYDLRETDGDRFEMVEDVVSTafpdferln-- 241 Nostoc sp. ...
jgi:Bind_0896    261 nglsdnafrehyghppwelvsefiqsfglayrvtapalelsqpYTFSLERTDTGATVQFGAlSSGEKVLLRFALSLFPFD 340 Beijerincki...
eebua:HCDSEM_037 133 --------------------------------------------------------------SGGERRLLELVQMVVMEP 150 Candidatus ...
jgi:Oter_3924    202 -------------------------------------------------------------lSQGTLHT-LAVLALASMP 219 Opitutus te...
Q7NJA5           236 --------------------------------------vphleAVYEHWRPNAGKQREDQF-SDGTLRLIGLFWALLETD 276 Gloeobacter...
ADC91575         255 ------------------------------------eflqtvrQSVKLTANLKNALINSDF-SNADARY-FLLVLLLFDP 296 Mageeibacil...
Q7UYP8           244 -------------------------------------rqpqyaIVGHLFNDKTLELKLSQE-SEGFRRFYAHLLALYQQP 285 Pirellula sp.
jgi:Sros_7563    253 vtvlpq---------------------lesidfeypsgaarevVVVLHERGLRRPTQLADA-SYGTIRLLGLLALLYDPR 310 Streptospor...
Q7UEM4           250 eeaf-------------------------pgsqlyvqsgengmQVVLTQPGMLRGLTAREL-SDGTLRYLLLLAALFSPR 303 Pirellula sp.
Q6AIC2           246 ----------------------------------------eevNISWRQNGSDYPMQPYHL-SDGSIRFICLATALLQPM 284 Desulfotale...
Q8YSF6           242 ----------------------------------fppvaagtiSMTWTDRNFSQPIYVHEL-SEGTLRF-LWLVTLLQSQ 285 Nostoc sp. ...
jgi:Bind_0896    341 PLrisiirpRLLLLDEMDASLHPemayRWLKGISd----GLVqKLG-----IKC-ILTTHS-PTTVA 396 Beijerinckia indica subs...
eebua:HCDSEM_037 151 ---------DVCVLDEVDSGLDA----HKLAILI-----KLVlAFGa---sRRClLVITHS-LDLML 195 Candidatus Hodgkinia cic...
jgi:Oter_3924    220 QPp------SVVCLEELDHGVHPrtlrELRDALYrlaypESV-GLKrp--aVQV-VATTHS-PYLLD 275 Opitutus terrae PB90-1
Q7NJA5           277 ---------SLLLLEEPELSLNS----GIVSRLP-----SIM-YRLqrqkrRQV-VISTHSyELLSD 323 Gloeobacter violaceus
ADC91575         297 KPr------SLLLLDAPESELYP----DKINSLA-----EQL-RRFsfktsSQI-LLTTHS-LGLVD 345 Mageeibacillus indolicus...
Q7UYP8           286 PK-------LAMLFEHPEDAVHP----GAFSLLAe----EFL-AAPme-grGQV-ILTTHS-PGLLD 333 Pirellula sp.
jgi:Sros_7563    311 PP-------ALTCVEEIDHGLHP----QALELLV-----ERL-REAse--rTQF-LIATHS-PAFAD 356 Streptosporangium roseum...
Q7UEM4           304 PP-------ELLVLNEPETSLHP----ELIEPLA-----NMI-CRAae--rSQV-IVVSHN-QQLVA 349 Pirellula sp.
Q6AIC2           285 PP-------AAIIIDEPELGLHP----AAIVILA-----ELI-QIAsq--kTQV-IIATQS-PALMD 330 Desulfotalea psychrophila
Q8YSF6           286 SLt------TITLLDEPEVSLHP----ELLRHLV-----YWM-REAsk--yTQL-IVATHS-DRLIR 332 Nostoc sp. PCC 7120
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