Conserved Protein Domain Family
AAA_21

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pfam13304: AAA_21 
AAA domain, putative AbiEii toxin, Type IV TA system
Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Statistics
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PSSM-Id: 315880
View PSSM: pfam13304
Aligned: 79 rows
Threshold Bit Score: 35.1052
Threshold Setting Gi: 0
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6KHU9         27 IIGIIGQNSSGKTIILETIELVfqimnmekflnsnlFSYQSFLNYLQkdnlGLNLISSYSPFYIHKKIEKFLNIlFFDKN 106 Mycoplasma mobile
35_pfamImport   1 LSVVAGANGVGKTSFARAL-----------------AGDSRYSVIAG----FEWARWRRGPGAVLGVFLTFQAP-VEVPG 58 
24_pfamImport   1 FNLVLGPNGSGKTSLIEALQHL-----------------------------------RTLSQLEPMDPITAHVT-EDGPS 44 
Q7NJA5         24 RVFVVGPNASGKSNFLDVFRFLrd-----------iAKPGGGLQKAVvargGVSKIRCLSARREPNIEIEIHISeSVNRS 92  Gloeobacter vi...
48_pfamImport   1 VSVLIGANNAGKSSVLQALDFLq-------------DCVLHGVTSAAqmngRHGFFDLRTRGTDEPMSLRILFS-SAKTG 66 
Q7UYP8         23 VTVLVGRSGTGKSNFVEAVRFLrdll------rgqpGGSGGGMGGVFgggqNPFALMRPLPMTEAPTRFEICFS-VRSSK 95  Pirellula sp.
46_pfamImport   1 VNVLIGPNGAGKTNVLKVFRFLadm--------irtDLIPAMDEHGGfdeiLFRGGESIPDHFRIKLKAAWTPHaTLEDS 72 
Q7UEM4         23 LTVVTGPNGSGKTNLYRSLRLIas----------aaNGNLNQSLAEEggfeSVLWAGPESIPNEMKRGDVPVQGtLRRKP 92  Pirellula sp.
Q6AIC2         41 LNVVVGGNGAGKSNLISFFKM---------------LRALIDGNLNRyvieHGGAGDLLFNGRKTTEKMEFETH-FNSRG 104 Desulfotalea p...
Q8YSF6         25 LIVMIGANGAGKTSFLDVL-----------------STLAASANGKLqetlQSKGGLNEILTRGKAQELEIEVSmRVPQE 87  Nostoc sp. PCC...
Q6KHU9        107 KKFVFNIFFQNGDNy------KMIISNQNENVSIFLYFNEILKEEILNFNNFIRNFYLYYFSFETKILNSKEEIEKIFFE 180 Mycoplasma mobile
35_pfamImport  59 VLYAHFLKLVACRA------------------------------------------------------------------ 72 
24_pfamImport  45 MVFQFTAPFERLQV---------RLACVDSNRCDAIHLTPPDAPDWPALKAEIERIRSFAFDPEAMASPTPLQPGAELAA 115
Q7NJA5         93 ALWRYEIGVKQETR----------GNRQPKLAYERVYKEDKLILDRPDEFDKNDDVRLTQTHLEQIVANLSFRDIAKFFE 162 Gloeobacter vi...
48_pfamImport  67 IIYNYMLQIGDNDQ----------GKPLITAESLQIVEQEKGDFFRCADDKFTARFGTHEESQVVKPYDLPLLSVYAKLP 136
Q7UYP8         96 ERYRYLLDLGKSPE-------QGRFGEEKLLLGDTILYHQSSDKNAMAWIQEPRLVDIPKPGGIALGRMPSLSDVVVAYA 168 Pirellula sp.
46_pfamImport  73 DEYELVVALNDPASqgqltrfERFKFPGPQGGNEILIRSDAVEVRAVSVRHTPSILDVLRSDAHMRTTGISSLSSGLSTL 152
Q7UEM4         93 IALKLAFSADPMSYci---dlGRPVPSNSMFDGDPEIKRECIWTGPTPDARSLCVDRKGANLRCRSGKGKWQDIDLHLSR 169 Pirellula sp.
Q6AIC2        105 YRFKLIPTPKDACS-------LEEEARYYESGLTGWWELGDSHDGTSRMVSEVTENRSDGQYSKPIYDAISSWQIYHFHD 177 Desulfotalea p...
Q8YSF6         88 QPLKYGLTLSPKGLsye--irNETLTQQRNPNKSEPFKYIESHGLDIKYFQEGSGLLRPNWEHNPLETSLSQVPKMYREP 165 Nostoc sp. PCC...
Q6KHU9        181 QNKKISNFKKEYEILNLEItylaesrpiDISNFNNRINYIFYFFKSQKIEDQYKKYKEKFLKWMKISDAWIDdfei---- 256 Mycoplasma mobile
35_pfamImport  73 ----------------------------GTAPSLACKLKLVLKLVGVSVRALNRPVNVGF-------------------- 104
24_pfamImport 116 DGANLAAVLADWRETARAA---------YDAFVAEALRLFPEYTKFELQSRPGHHVALAFTLLGEVGVVSGEd------- 179
Q7NJA5        163 SVLYLHLVPQLLRHPEAFSgpa----ipEDPFGRSFLERVAKTPEKTRRARLLKIEEALKFAVPQLKKLSDVrdelg--- 235 Gloeobacter vi...
48_pfamImport 137 GADFCREPYEYIEHWLYISfp-----alMNQPGRASRDFMLQASQLGNLSGGHRHINRYADNVPNVLAYLQKkhpniyq- 210
Q7UYP8        169 ALTEGIGCYTFPNSVMLIGapa---eagQSGFQDSGANYLDTMKKIVSNFQDASARQRIVKSLQRVNEGVSSvelndl-- 243 Pirellula sp.
46_pfamImport 153 PRLSEEAGAREVRALASRLg--------EFRVFDVSVDAARRPSRLLQRGGDSLEDDAANLAAFLLTLRKEDsdawsrle 224
Q7UEM4        170 GTSLMTEYADPFAAPEIIVmke---qlrGWRFYDTFRCDSHAPARLPSPQTFTPVMANDGSNLAAALQTIREigdshive 246 Pirellula sp.
Q6AIC2        178 TGSRAGMRHYEIIQDNKSLr--------ADASNIGPFLLKLKKKHPQEYKDILNAIRLVTPFFEDFLLEPREsgnk---- 245 Desulfotalea p...
Q8YSF6        166 ENLRKSLASCTYYGALDVSek-----spIRLPQPMRPAKLPGASGEDLVSCLYDLRETDGDRFEMVEDVVSTafpdferl 240 Nostoc sp. PCC...
Q6KHU9        257 ----------------------qndFYWYFKNTKGELINWNQLSKGTQKWaAFFYDIISRYLLKdkitvnknIFFLIDEI 314 Mycoplasma mobile
35_pfamImport 105 -------------------------------------------SGGERRL-LELVQMVVMEP----------DVCVLDEV 130
24_pfamImport 180 ------------------------------------------lSQGTLHT--LAVLALASMPQPp-------SVVCLEEL 208
Q7NJA5        236 --------------------vphleAVYEHWRPNAGKQREDQFSDGTLRL-IGLFWALLETD----------SLLLLEEP 284 Gloeobacter vi...
48_pfamImport 211 ------------------eflqtvrQSVKLTANLKNALINSDFSNADARY--FLLVLLLFDPKPr-------SLLLLDAP 263
Q7UYP8        244 -------------------rqpqyaIVGHLFNDKTLELKLSQESEGFRRF-YAHLLALYQQPPK--------LAMLFEHP 295 Pirellula sp.
46_pfamImport 225 edavtvlpqlesidfeypsgaarevVVVLHERGLRRPTQLADASYGTIRL-LGLLALLYDPRPP--------ALTCVEEI 295
Q7UEM4        247 qaieeaf----pgsqlyvqsgengmQVVLTQPGMLRGLTARELSDGTLRY-LLLLAALFSPRPP--------ELLVLNEP 313 Pirellula sp.
Q6AIC2        246 ----------------------eevNISWRQNGSDYPMQPYHLSDGSIRF-ICLATALLQPMPP--------AAIIIDEP 294 Desulfotalea p...
Q8YSF6        241 n---------------fppvaagtiSMTWTDRNFSQPIYVHELSEGTLRF--LWLVTLLQSQSLt-------TITLLDEP 296 Nostoc sp. PCC...
Q6KHU9        315 ENFMHL----KLTKTFI-----DLMiqyfenNLNnsigkIHL-IYTTHQ-PLLFE 358 Mycoplasma mobile
35_pfamImport 131 DSGLDA----HKLAILI-----KLVl-----AFGa---sRRClLVITHS-LDLML 167
24_pfamImport 209 DHGVHPrtlrELRDALYrlaypESV------GLKrp--aVQV-VATTHS-PYLLD 253
Q7NJA5        285 ELSLNS----GIVSRLP-----SIM------YRLqrqkrRQV-VISTHSyELLSD 323 Gloeobacter violaceus
48_pfamImport 264 ESELYP----DKINSLA-----EQL------RRFsfktsSQI-LLTTHS-LGLVD 301
Q7UYP8        296 EDAVHP----GAFSLLAe----EFL------AAPme-grGQV-ILTTHS-PGLLD 333 Pirellula sp.
46_pfamImport 296 DHGLHP----QALELLV-----ERL------REAse--rTQF-LIATHS-PAFAD 331
Q7UEM4        314 ETSLHP----ELIEPLA-----NMI------CRAae--rSQV-IVVSHN-QQLVA 349 Pirellula sp.
Q6AIC2        295 ELGLHP----AAIVILA-----ELI------QIAsq--kTQV-IIATQS-PALMD 330 Desulfotalea psychrophila
Q8YSF6        297 EVSLHP----ELLRHLV-----YWM------REAsk--yTQL-IVATHS-DRLIR 332 Nostoc sp. PCC 7120
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