4XGT,4U4C


Conserved Protein Domain Family
rRNA_proc-arch

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pfam13234: rRNA_proc-arch 
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rRNA-processing arch domain
Mtr4 is the essential RNA helicase, and is an exosome-activating cofactor. This arch domain is carried in Mtr4 and Ski2 (the cytosolic homolog of Mtr4). The arch domain is required for proper 5.8S rRNA processing, and appears to function independently of canonical helicase activity.
Statistics
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PSSM-Id: 338640
View PSSM: pfam13234
Aligned: 289 rows
Threshold Bit Score: 39.0596
Threshold Setting Gi: 574751826
Created: 29-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4XGT_A        523 EYMLERCFFQFQNAASVPQLEREL-ISLQQERDAIIIP----DESIVKDYYGVRQQLEEYNKDMVFVIQHPQNCLGfFQE 597  Neurospora cr...
XP_009149949  709 EDMLKRSFAEFHAQKKLPEKQQLLmLKRSLPVKTIECIk---GEPAIEDYYEMYMEANECNSKMSEAVMQSPNTQQhLVP 785  field mustard
XP_003552970  838 EDMLKRSFAEFHAQKKLPEMQQLLkRKLNQPTKAIECLk---GEPTIEEYYDLYLEAETYSNQISEAILQSPSAQQfLNT 914  soybean
ERN09667      924 EDMLKRSFAEFHAQKTLPEKQRLLlQKLAQPTKDIECIk---GEPAIEDYYKIAIEAEKYREHILEVVMQSQTAHQfLSP 1000 Amborella tri...
EMS49465      936 EDMLKRSFAEFHAQKDLPQKEKLLlQMLRQPTKTIECIk---GEPSIEEYYDMFLEAEEHREFVTEAIMQLHTTQQfLAP 1012 Triticum urartu
XP_020181535  865 EDMLKRSFAEFHAQKDLPQKEKLLlQMLRQPTKTIE-Ci--kGEPSIEEYYDMFLEAEEHREFVTEAIMQLHTTQQfLAP 941  Aegilops taus...
XP_003570958  868 EDMLKRSFAEFHAQKKLPEKEELLlQMLRQPTKTIECIk---GEPSIEEYYDMFLEAEKLREYITEAIMQLPASQQfLGP 944  Brachypodium ...
XP_006646905  869 EDMLKRSFAEFHAQKNLPEKEKLLlQMLRQPTKTIECIk---GEPAIEEYYEMALEAEAHRESITEAIMQLSASQQaLIP 945  malo sina
XP_009416213  837 EDMLKRSFAEFHAQKNLPEKERLLlQKLRQSTKKIECIk---GEPAIEEYFEMASEAETHRQHILEAVLQSHTAQQfLSP 913  wild Malaysia...
XP_003288018  829 EDMIKRSFSEFSSQQEIPDIEKQI-SKLTEQYKSLGEIecilGEPDIENYYSLFSQSKNINERIQKTILNLPNSNH-FSP 906  Dictyostelium...
4XGT_A        598 GRLIHikspsgvdygwgvlikhiqrqtpkngqppypeqesyvldv---------------------------llkvsgdf 650  Neurospora cr...
XP_009149949  786 GRVVVmksetgidnllgvvlkglsnrqyvvlvikseipppeknmvsidkkssdps------qgffiapkskrgfeddyys 859  field mustard
XP_003552970  915 GRVVIvksesaqdhllgvvvetpsptnkmyivfvikpdmpssvdnasssgnmqnksga-fdqgyfvmpksrrvvvdeyst 993  soybean
ERN09667     1001 GRVVVvksrlahehilgvilktpaagnkhhivfaldaeyprynattslsnkfqdkesgnfpqgvvitpkakrrpdekyfl 1080 Amborella tri...
EMS49465     1013 GRLVVvksksdddhllgvivknpsttlkqyvvlvltgdcpssalapnlssqnekgpgd-sqgyfiippkgkrgmdddffs 1091 Triticum urartu
XP_020181535  942 GRLVVvksksdddhllgvivknpsatlkqyvvlvltgdctssalapnlssqsekgpgd-sqgyfiippkgkrgmdddffs 1020 Aegilops taus...
XP_003570958  945 GRLVVvesksdddhllgvivknpsgslkqyvvfvltgectssalapnlsnqndnaqgevqqgymvippkgkrgmddeffs 1024 Brachypodium ...
XP_006646905  946 GRLVVvksksdddhllgvivktpsaalkqyivlvltgdctssalapdssnqnekeagd-fkqgyfvvpkgkrgmedeyfs 1024 malo sina
XP_009416213  914 GRVVVvksqsaedhllgtvlktpsaankqyiilvliadiasqapsmssnklqeeesqn-fqqgyfitpkgkrsmdeeyfs 992  wild Malaysia...
XP_003288018  907 GRVLVlsnddemkynsytigviiqcnteiikqyt---------------------------------------------- 940  Dictyostelium...
4XGT_A        651 npktrgegpmpegimpagkdsknarwevvpcLLNCLRALGQLRVFLpkR--Les-adEKDGVGKAVDEISRrfp-----d 722  Neurospora cr...
XP_009149949  860 tsssrkgtgvikielpyhgvaagvgyevrafDNKEVLCICVSKIKI--DqvRlledgNKAAFSQTVQQLLDlksd--gnk 935  field mustard
XP_003552970  994 svsarkgkgvitirlpysgsacgmgyevrevDSKEFLCICSSKIKI--DrvGllediSSSVYSKTVQLLMDlksd--gnk 1069 soybean
ERN09667     1081 ttsshkgsgvinitlphkgnaagvnyvvmevESNDILSICNCKIKI--DqvRlledvSTAACSRTVQQLVDlkkq--dnk 1156 Amborella tri...
EMS49465     1092 ssrtrkssgviniklpytgdasgmgfevravENKEIISICTSKIKI--DqvGllediSKTAYAKTVQMLIKeqtd---gk 1166 Triticum urartu
XP_020181535 1021 ssrtrkssgviniklpymgdasgmgfevravENKEIISICISKIKI--DqvGllediSKTVYAKTVQMLIKeqtd---gk 1095 Aegilops taus...
XP_003570958 1025 agstrkssgvikiklphkgdasgmgfevravENKEIVSICTSKIKI--DqfRlleepSKTVYSTTVQLLIKaqpd--ghk 1100 Brachypodium ...
XP_006646905 1025 svskrkgsgviniklpykgdasgtgfevraiDSKEIMSICTSKIKI--DqvGlledpSKTIYAKTVQMLKQeqpd--gnk 1100 malo sina
XP_009416213  993 svssrkgsgainiklpyygsasgtnykviaiDNKDIVSICNCKIKI--DqvRlledpSNIAYSKTVQQLLEkkhd--gnk 1068 wild Malaysia...
XP_003288018  941 --nnqvnrtfkifslksssnnafeghqitisNGSDIKKVCDEKIKVd---iKliesaDPIATNSLEQQLQRiieeyplpl 1015 Dictyostelium...
4XGT_A        723 gIPILDPmENMGINDDSFKKLLRKIEVLESRLvAnpL-HnS---PLLVELWNQYSLKMQLGEQIKEKK 786  Neurospora crassa
XP_009149949  936 fPPALDPvKDLKLKDAELVETYYKWTSLLQKM-S--MnK-ChgcVKLDEHMKLAREIRKHKKDLKDLE 999  field mustard
XP_003552970 1070 yPPALDPvKDLKLRDVKLVATYHKWTRLLEKM-S--QnQ-ChgcIKLEEHLKLAKEIKKHKEEVYALQ 1133 soybean
ERN09667     1157 fPPAVDPvKDLKLKDMDLVFEYNKYNNLLQKM-A--QsK-ChgcIKLEQHIALLKEQTKHIEEVNALK 1220 Amborella trichopoda
EMS49465     1167 yPPALDAiKDLKMKDMDQVKRYHAHNNLLEVM-S--KnK-ChgcIKLKEHKSMMKDQKVHKDELDQLK 1230 Triticum urartu
XP_020181535 1096 yPPALDAiKDLKMKDMDQVKRYHAHNNLLEEM-S--KnK-ChgcIKLKEHKSMMKDQKMHKDELDQLK 1159 Aegilops tauschii subsp. ...
XP_003570958 1101 yPPALDPiKDLKMKDMDQVQKYHAYNRLLEKM-S--EnK-ChgcIKLKEHKSLMKEQKVYKTQMDELK 1164 Brachypodium distachyon
XP_006646905 1101 yPAALDAiKDLKLKDMLLIENYHAYQRLLQKM-S--EnK-ChgcIKLKEHIALMKEQKVYKDQLSELK 1164 malo sina
XP_009416213 1069 yPPALDAvKDLKLRDMDLVQRYHSYNKLLQNM-A--EnK-ChgcIKFNEHIMLIKEQNRHKEEVNALK 1132 wild Malaysian banana
XP_003288018 1016 gPKAIDPiHQLKLKDVNFVTTYEHLEKIEKLI-P--QsK-ChkcPRLAEHYELTEKKHQLQEAIRDYK 1079 Dictyostelium purpureum
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