5EAN


Conserved Protein Domain Family
AAA_12

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pfam13087: AAA_12 
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AAA domain
This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Statistics
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PSSM-Id: 338594
View PSSM: pfam13087
Aligned: 110 rows
Threshold Bit Score: 161.172
Threshold Setting Gi: 156395603
Created: 29-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5EAN_A        809 MSESLFKRL-ERNe----------------SAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGS------DrvanavLALP 865
gi 121955480  441 LGMSMLERLmNLPvyqkdpi----tklyntQLITKLVKNYRSHEALIKFSNEQFYDGELQCLA------S------SQVS 504
gi 123889019  725 LDVSLLERLmTQNdlykrg-----dvefdnRYVSKLIMNYRSHPYILEVPNRLFYDGELKACA------D------EISS 787
gi 50403726   699 lgYSLLERLlAYNslykkg-----pngydpQFITKLLRNYRSHPTILDIPNQLYYDGELQACA------D------VVDR 761
gi 156395541  203 LNVSLLERLmSGLlyardetrfvdhgcydpLLVTKLVNNYRSHPSLLRLPSALFYHSELRVCA------E------RTMR 270
gi 290975853  644 LGESLLEHLvKLGdn--------------cCSITQLQQSYRAHPKIMQVYSSVFYNNSLISSCtdinsaN------LFIN 703
gi 156395603  654 LDRSLLVRLyELYpr-------------esDSKLLLLENYRAYNDIVEIPSKLFYEGTLIAHK------H------RPEG 708
gi 260831591 1815 FDKSLLERMvQRYiefgkakg--ttekaenPFLVMLKDNYRCCEEILRFLSESFYGGL-----------K------SMGQ 1875
gi 260833184  814 FHQSLLERLfYHYqqmvp-------dddlhPCITLLHENYRCHDDILKFPSKVFYGGKLICRS------E------AKRH 874
gi 156395603 2603 LGRSLFEDLwEAHre-------------gsSACCTLNTQHRMHPSLGKFSSSFFYN--VQQSRenvsnaC------AREL 2661
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5EAN_A        866 NLKda-rLslqlyadysdspwlagVLEPDNP-VCFLNTDKVPAPEQVe-nGGVSNVTEARLIVFLTSTFIKAGCSPs--- 939
gi 121955480  505 LAEnw-rW----------------LPNKTFP-IILHTVFGSNKRSQKs--KSFMNQTEIDTVEFYLDFLLKTGINDrkia 564
gi 123889019  788 NQYcmweH----------------LPSKGFP-VIFHGVPGKDERESNs--PSFFNIYEINILVDYLKKLLLTQPKKgisr 848
gi 50403726   762 ERFcrweG----------------LPQQGFP-IIFHGVMGKDEREGNs--PSFFNPEEAATVTSYLKQLLAPSSKKgkar 822
gi 156395541  271 EQLsqweM----------------LPTQGTP-LVFHGLKGEDMREGNs--PSWFNPVEAVQVVRYVQALKNSATCPikl- 330
gi 290975853  704 NPI---------------------LENPQVP-MLFYHVKGDEKRDNDs--PSWYNSKEIQVLMDKLDEIVKSGLVFnskh 759
gi 156395603  709 SEY---------------------------P-IRFHGVLGREERAVDr--ASYYNMAEAAEVSERVEELVKQWRGEdaed 758
gi 260831591 1876 PRY-----------------------PRWYP-LTFFSAEGDDKTGDYs--TSFFNMAEVLEITERVQQLWKDWPEEwgpp 1929
gi 260833184  875 PNF--------------------------FP-LAFYAVAYGQDSVDNt-sTSFYNDAEVWELADRVEALWNSWPEEewge 926
gi 156395603 2662 EGF---------------------WPAGRDLyHVFCHVEDEPESDCDyieGGMSNDAEVQKVVEVVESLMSRGVQPf--- 2717
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5EAN_A        940 -------dIGVIAPYRQQLRIISDLLARSSVGm--------VEVNTVDKYQGRDKSLILVSFVRS-----------N--- 990
gi 121955480  565 -----qedIGIISPYQLQVQRLKQMCQDKQWPs--------LEIGSVEQFQGREKLVIILSTARS--------------- 616
gi 123889019  849 i---fpkdIGIIAPYRKQVEKIKRAIDA-DKDfqdymgidnLKVGSVEEFQGQERKVIMVSTVRSs----------Vkyi 914
gi 50403726   823 l---sprnVGVISPYRKQVEKIRYCITKLDRElrglddikdLKVGSVEEFQGQERSVILISTVRS-----------S--- 885
gi 156395541  331 ------adLGIITPYKKQVEKIRLLLSRVGIDe--------VKVGSVEEFQGQERPAIIISTVRSt----------Eamv 386
gi 290975853  760 nqynpeheIGIITPYRKQAEEIKKLLR-KSTNply----kkIFVGTTEQFQGQERRVILLTTVRS-----------Sste 823
gi 156395603  759 v---elrrICVLTPYTAQVREIRQLLRRSQLGe--------VRVESVNNVQGLEFDALFISTVHTa---------fGltp 818
gi 260831591 1930 ----nmadIGVITPYHNQMQLIRKELRQKRMGg--------VTVEMVTNIQGKQFRAVFISTVRT-----------Ratc 1986
gi 260833184  927 kntismaqIGVVTPYQDQVNRIRLALRRKRLGr--------VTVETVTNVQGKEYRALFLSTVRTretccgeqnisTqgt 998
gi 156395603 2718 -------kIWIVSPFLRQRHSILHALDSTLGSql------dIRLTSPEECQGAQCDVLVLSTVRG-----------Rprd 2773
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
5EAN_A        991 ---EDG-------TLgeLLKDWRRLNVALTRAKHKLILLGSVS 1023
gi 121955480  617 ---HTP-------DVg-FLNNVKRLNVALTRAKALLIVIGNSN 648
gi 123889019  915 sldETF-------NIg-FLKNEKRFNVAVTRAKSLLIMVGNPM 949
gi 50403726   886 ---QSFvqldldfNLg-FLKNPKRFNVAVTRAKALLIVVGNPl 924
gi 156395541  387 gfdVAH-------TIg-FLDNPKRFNVAVTRAQSLLVVVGNPH 421
gi 290975853  824 gleQDSk-----fKLg-FLQNPKRLNVAISRAISLMVIVGNAE 860
gi 156395603  819 emlDNH-------HLg-FLSDPRLLNTAVTRAKYHLTIVGDPN 853
gi 260831591 1987 dpnNDKn------SYg-FLSDSKLLNTAMTRAQSLVAVIGDPR 2022
gi 260833184  999 dkeQTS-------DFr-FLSDPKLLNTAITRAKSFVGVVGDPV 1033
gi 156395603 2774 qltGPHg------GFg-CLGDKHQMNVVLTRARKGLVIVGNRY 2809
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