1VIG,2CTK,1WVN,1J4W,2JZX,1DTJ,2ANN,2ANN,1WE8,1X4M


Conserved Protein Domain Family
KH_3

?
pfam13014: KH_3 (this model, PSSM-Id:289762 is obsolete)
Click on image for an interactive view with Cn3D
KH domain
KH motifs bind RNA in vitro. This RNA-binding domain is required for the efficient anchoring of ASH1-mRNA to the distal tip of the daughter cell. ASH1 is a specific repressor of transcription that localizes asymmetrically to the daughter cell nucleus. RNA localization is a widespread mechanism for achieving localized protein synthesis.
Statistics
?
PSSM-Id: 289762
View PSSM: pfam13014
Aligned: 719 rows
Threshold Bit Score: 26.6633
Threshold Setting Gi: 74630263
Created: 14-Jul-2015
Updated: 5-Aug-2015
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1VIG_A         15 FHRHLIGKSGAN---INRIKDQY-KVSVRIPP-----DsEKSNLIRIEG 54   human
Q4P7S6        759 HREFISGKKNGK---VNKVMKQC-GVRIKFET-----FnDYNFLIDVSG 798  Ustilago maydis
EDK38110      592 HYMLMINAKNKNlnfVNELEIKH-GVYIDFPKsveafQnSNELTVSIRG 639  Meyerozyma guilliermondii ATCC 6260
XP_001729217  606 HREFISGKKNGK---INKIMEGC-GVRIRFEP-----FnDYNFLIEVLG 645  Malassezia globosa CBS 7966
KKK23718      515 HKEFVSGKKNGK---INKIMGQS-NVQIIFDG-----FnEYNFYIDVCG 554  Aspergillus ochraceoroseus
KIK02300      466 HREFISGKKNGK---INKIMQTT-NVKIKFET-----FnDHNFLIDIAG 505  Laccaria amethystina LaAM-08-1
XP_001747904  922 YFKDMLARRAAF---LQDLAQEFpTCHVKVPRpd--aEgNCSNTVNVRG 965  Monosiga brevicollis MX1
XP_002174831 1075 LAQRLL--QSNI---LRNAYSRH-HVYVDRPHk----MeAGKTTIAVIA 1113 Schizosaccharomyces japonicus yFS275
NP_001100438  549 VRDSIFGFGGKY---IHRLNEQL-HVDIRLPP-----KgSWNTNITVIG 588  Norway rat
XP_002172284  261 LAQSVLSRSPTK---LQEVAQDC-NTQIELPQa---dAqNDEQILLISG 302  Schizosaccharomyces japonicus yFS275
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap