1VIG,2CTK,1WVN,1J4W,2JZX,1DTJ,2ANN,2ANN,1WE8,1X4M


Conserved Protein Domain Family
KH_3

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pfam13014: KH_3 (this model, PSSM-Id:289762 is obsolete)
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KH domain
KH motifs bind RNA in vitro. This RNA-binding domain is required for the efficient anchoring of ASH1-mRNA to the distal tip of the daughter cell. ASH1 is a specific repressor of transcription that localizes asymmetrically to the daughter cell nucleus. RNA localization is a widespread mechanism for achieving localized protein synthesis.
Statistics
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PSSM-Id: 289762
View PSSM: pfam13014
Aligned: 719 rows
Threshold Bit Score: 26.6633
Threshold Setting Gi: 74630263
Created: 14-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
1VIG_A         15 FHRHLIGKSGAN---INRIKDQY-KVSVRIPP-----DsEKSNLIRIEG 54
gi 74701299   759 HREFISGKKNGK---VNKVMKQC-GVRIKFET-----FnDYNFLIDVSG 798
gi 190346104  592 HYMLMINAKNKNlnfVNELEIKH-GVYIDFPKsveafQnSNELTVSIRG 639
gi 164656178  606 HREFISGKKNGK---INKIMEGC-GVRIRFEP-----FnDYNFLIEVLG 645
gi 816348024  515 HKEFVSGKKNGK---INKIMGQS-NVQIIFDG-----FnEYNFYIDVCG 554
gi 750944378  466 HREFISGKKNGK---INKIMQTT-NVKIKFET-----FnDHNFLIDIAG 505
gi 167527143  922 YFKDMLARRAAF---LQDLAQEFpTCHVKVPRpd--aEgNCSNTVNVRG 965
gi 213408120 1075 LAQRLL--QSNI---LRNAYSRH-HVYVDRPHk----MeAGKTTIAVIA 1113
gi 157820101  549 VRDSIFGFGGKY---IHRLNEQL-HVDIRLPP-----KgSWNTNITVIG 588
gi 213403023  261 LAQSVLSRSPTK---LQEVAQDC-NTQIELPQa---dAqNDEQILLISG 302
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