Conserved Protein Domain Family
ANAPC4_WD40

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pfam12894: ANAPC4_WD40 
Anaphase-promoting complex subunit 4 WD40 domain
Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Statistics
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PSSM-Id: 372368
View PSSM: pfam12894
Aligned: 24 rows
Threshold Bit Score: 109.288
Threshold Setting Gi: 699749056
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEA25475             41 LTYCPTMDLIALATEDEQLYVFRLNG--------QEVLSAdlagdpylDEVKGEIR--GVRWKNDGRLLAVADAENKLRI 110 Talaromy...
jgi:MICPUN_58493     27 ASWCPTMDLLALATSDGQLALSRLDWnktggereNRLWTA---------NPDSPVT--SLGWRPDGKILVSGHADGAVQL 95  Micromon...
EDQ90924             25 QSWCPTMDILVLAFEDGSIEARRLSW--------QLAWQVs------pPALDAAVT--HLAWSPSGKRLLVLHADGHCRI 88  Monosiga...
WGS:AATM:SJAG_02186  33 LSLCPTMDLQAFVTDANQLYVCRRNG--------HIIWEL---------KRDETVT--ALCWHFKGEMLAVGYGNGEIEL 93  Schizosa...
O42839               33 VILCPSMELIAILTCSNHLICCRSNS--------QRIWDV--------DFHDLEAT--ELCWNHDGNLIVVGFKNGELKI 94  Schizosa...
Q6BWV1               23 LSWCPTMDLLAISMNRMSIWVFRING--------ERIYSI---------NNKSLIL--DISWNPNGKFFCVSGIDGYCKI 83  Debaryom...
EDO04643             24 LAYCPSMDLIALGSTDQQVLIYRLNG--------QRVYGAa------qKVNTLRVE--KISWKPNGQLLAIAWSDGSVRL 87  Scleroti...
EEQ27150             36 FAYCPNMDLVAIVTEDEQLNAYRLNG--------QRVFGGaygl-gedDGKGGLVRavGLKWKENGRVLAVACSDNRIRL 106 Microspo...
WGS:ABKI:PADG_06682  26 MSYCPTMDLIALASADERVDVFRLNG--------QRVFGGvygg-ggrGGSGREVR--GLKWKGNGHLLAVVCSDNIIRI 94  Paracocc...
EEP77994             45 LTYCPTMDLVALATEDEQVHVFRLNG--------QKVFGGfarg-ggaAADGLKVK--SLKWKGNGHLLAVATSDNNVRI 113 Uncinoca...
EEA25475            111 ISSYTGKTVHHFSCLPHeaeghssspn---estkdpkdirITCIGWGVN 156 Talaromyces marneffei ATCC 18224
jgi:MICPUN_58493     96 YHAEDGEVLHASTPHRGs---------------------aVTSLHWQDA 123 Micromonas commoda
EDQ90924             89 FNAENGQPLSHFDAGAP-----------------------PSAVFWAST 114 Monosiga brevicollis MX1
WGS:AATM:SJAG_02186  94 LEVVNGRTAEKIQTGSTg---------------------rITSIAWSVQ 121 Schizosaccharomyces japonicus yFS275
O42839               95 IDSSTGHLVEQRPASRDl---------------------aVLMITWAMQ 122 Schizosaccharomyces pombe 972h-
Q6BWV1               84 YDSNSGKLINTIDSKQKs----------------------INLINWCYH 110 Debaryomyces hansenii
EDO04643             88 VGAESTKVVHHFSTTSDdqd-----------------fsgITCMSWSSN 119 Sclerotinia sclerotiorum 1980 UF-70
EEQ27150            107 LSSYSGKMVHSLTAQSApipfslp----------qkpagtVSCIGWGVS 145 Microsporum canis CBS 113480
WGS:ABKI:PADG_06682  95 LSAYSGKIVHQLPCGPLlashstasvppsslspaadavtcVSCLGWGMN 143 Paracoccidioides brasiliensis Pb18
EEP77994            114 LSAYSGKTVHVLPCNASleygvgvrpr----epvpnvapsICCLGWGVN 158 Uncinocarpus reesii 1704
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