Conserved Protein Domain Family
AAA_10

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pfam12846: AAA_10 
AAA-like domain
This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Statistics
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PSSM-Id: 315512
View PSSM: pfam12846
Aligned: 11 rows
Threshold Bit Score: 406.012
Threshold Setting Gi: 81536497
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81838800  443 KI-VWFFPNLTK-KAIEGAQYTNGNT-LIIGPPGQGKSVLVKYIFLWLTFLG---------QKILYIDPKNE-TVLfF-- 507
gi 123066446 443 RN-VYLQPSLAS-QGVKGTVTNALAS-AFVGSLGGGKSFCNNLLVYYAVLFG---------GQAVILDPKAE-RGN-W-- 506
gi 81436856  443 RN-VYLKPALAS-QGVKGSVTNALAA-AFLGSLGGGKSFSNNLLVYYAVLFG---------GQAVIVDPKGE-RGG-W-- 506
gi 81436596  443 RN-VYLKPALAS-QGVKGSVTNALAA-AFLGSLGGGKSFSNNLLVYYAVLFG---------GQAVIVDPKGE-RGG-W-- 506
gi 81509530  444 KN-VYLKPALAS-QGVKGSVTNALAS-AFIGSLGGGKSFSNNMLVYYAVLFG---------GQAVIVDPKAE-RGK-W-- 507
gi 81345928  442 RDfVLFHPFLAN-QQLKGSKTRSPHC-LITGDTGNGKSYLAKLIFNYISMLN---------IKSLYIDPKKE-MRK-Wiq 508
gi 81437537  443 KNiVYMNLLLANkQNIEGKKTNNPHW-LVSGDTGNGKSVFSKWLFLYSSLLD---------VKVLYIDPKKEvRQQ-F-- 509
gi 81436451  444 KNlIFMNMLLANkEGVDGKKTNNPHW-ALTGDTGNGKSVTAKTLFMQMALLK---------DRVLYIDPKKEmRKQ-F-- 510
gi 123525120 425 AP-VWWRPGYAA-RELGR--SNAV---FITGGLGGGKSMTIKTMGHFIRLAG---------GVLFVIDPKKN-EYR-A-- 484
gi 81536497  447 RP-VLIDP-------TRGPRENASGSmAFIGELGAGKSVGMKTAVYNVLARGhqpgrphsrGRAVIVDRTKE--EE-W-- 513
gi 727330608 177 KI-VWFFPNLTK-KAIEGAQYTNGNT-LIIGPPGQGKSVLVKYIFLWLTFLG---------QKILYIDPKNE-TVLfF-- 241
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81838800  508 --------KRALdkfghiPEfk-------aLYQ--R----------INFVSL-S-SE-ERYRGMLDPLLFLP--RE-EAI 554
gi 123066446 507 --------KETL------PE----------IAN--E----------INIVNL-T-SD-KDNAGLLDPFVIMK--NVkDAE 545
gi 81436856  507 --------KENL------PE----------IAD--E----------INILNL-T-SK-PENQGLLDPYVIMK--KKkDSE 545
gi 81436596  507 --------KENL------PE----------IAD--E----------INILNL-T-SK-PENQGLLDPYVIMK--KKkDSE 545
gi 81509530  508 --------KETL------PE----------IAH--E----------INIVNL-T-SD-DENKGLLDPYVILS--RKkDSE 546
gi 81345928  509 rvlndeyiRENF------PLy---------IAHleK----------YNYITL-D-HEnTHNWGALDPISFLP--PMkAKE 559
gi 81437537  510 --------MRTIn----dPE----------YQR--KypldvafiktFNFVTL-DvRK-KENHGVLDPIVLFD--ET-EAI 560
gi 81436451  511 --------MYTIn----dPEyqkkypldvdFVK--S----------FNFVTLdV-RD-TKNHGVLDPIVLFD--ETeAIA 562
gi 123525120 485 --------YERL------YP--------------------------IKRIDL-S-PG-GDQ--ELNPFMLAA--DErRSK 517
gi 81536497  514 --------VRFA------KA----------CPG--T----------TQVIRI-D----QEAEVSLDPLRLFNadSPkIAA 552
gi 727330608 242 --------KRALdkfghiPEfk-------aLYQ--R----------INFVSL-S-SE-ERYRGMLDPLLFLP--RE-EAI 288
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81838800  555 QTARNVLENfgeVTTDS--HTASDKKTLILDS---VNAVM-K---GKGkKHLTKVIEVI---R---EK--DPKLANLI-- 615
gi 123066446 546 SLAIDILTF---LTGIS--SRDGEKFPVLRKA---VRSVT-Q---SET-RGLLHVIEEL---R---KE--DTAISRNI-- 602
gi 81436856  546 SLAIDILTF---LTGIS--SRDGEKFPVLRKA---IRTVT-Q---SDQ-RGLLQVINEL---R---KE--NSPVAENI-- 602
gi 81436596  546 SLAIDILTF---LTGIS--SRDGEKFPVLRKA---IRTVT-Q---SDQ-RGLLQVINEL---R---KE--NSPVAENI-- 602
gi 81509530  547 SLAIDILTF---LTGIS--SRDSDKFPVLRKA---IRNVT-Q---SEQ-RGLLLVIDEL---R---KE--DTSISNSI-- 603
gi 81345928  560 LV-QVIFEQ---VYDFK--GKDDINTAFLRATsevIDAKQ-K---GEQ-VGSLDIIRKM---Q---SH--PEEAVQKA-- 618
gi 81437537  561 ATAKAMLNN---INEDK--WKMPHKTA-INET---VAEVVaErkaGKQ-VGFWHVIERL---I---SH--SEKDVHEM-- 620
gi 81436451  563 TTKAMLTNI---YEGTWnlKQKTEINEAIAKV---VLERK-E---GKK-VGFWHVIERL---V---ES--EISDVKDM-- 621
gi 123525120 518 GIALDFLSI---ALNLR--DDNDVRRVAVSQA---VERVA-Gr-pPAE-RNLEACLEEL---NmmaKEkaHPQVAREAgq 583
gi 81536497  553 RFCESFLTL---LLGVK--PMELEGV-ALSEA---VEAVL-E---RPD-PSMTALVDELverG---RT--DDVAGRNL-- 611
gi 727330608 289 QTARNVLENfgeVTTDS--HTASDKKTLILDS---VNAVM-K---GKGkKHLTKVIEVI---R---EK--DPKLANLI-- 349
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81838800  616 -SGHN-----VGLGKILLGND-YSEPIRFENQINVLGTQGLKIP-T--Q-----AEIdSGRLNNEQIAGMSIMEVIMKMT 680
gi 123066446 603 -ADHIdsftdYDFAHLLFSDGtVENAISLDNQLNIIQVADLVLP-D--K-----DTT-FEEYTTIELLSVSMLIVISTFA 672
gi 81436856  603 -ADHIesftdYDFAHLLFSDGsITQSISLDKQLNIIQVADLVLP-D--A-----ETT-FEEYTTMELLSVSMLIVISTFA 672
gi 81436596  603 -ADHIesftdYDFAHLLFSDGsITQSISLDKQLNIIQVADLVLP-D--A-----ETT-FEEYTTMELLSVSMLIVISTFA 672
gi 81509530  604 -ADHIesfvdYDFAHLLFSDGnVTQSISLEKQLNIIQVADLVLP-D--A-----DTS-FEEYTTMELLSVAMLIVISTFA 673
gi 81345928  619 -GDYLnevvsDSILKLCIHDGs-NPALSLEKRITILEVENMDLP-D--H-----AER-LENYTISQLKSSAVMFALGKFC 687
gi 81437537  621 -GRFLlstikGSILELAFSHGeVEG-LSFEKKVTILEIEDLDLP-T--D-------R-HDELDENQRLSVTLMFALGTFC 687
gi 81436451  622 -GRFIlstvkGSVLELAFSHGdVEG-LSFDKKVTILEIEDLDLPtD--K-----NEN-LDEN---KRLSVTLMFALGTFC 688
gi 123525120 584 cALLLeslrdGSLGHLVFGKGrG-NEIS---PVTVVSLQGLPLP-RtaQ-----NLL-AGRITESERQGLGMLYLAAAMA 652
gi 81536497  612 -ARKLkavarKDLAAVVFDDTl-PVVDTRRADTVVFAVNSLQLP-K--KaeltsDHR-IERLEFEKVLGRAVMYLIAAVA 685
gi 727330608 350 -SGHN-----VGLGKILLGND-YSEPIRFENQINVLGTQGLKIP-T--Q-----AEIdSGRLNNEQIAGMSIMEVIMKMT 414
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81838800  681 TIF--ST-DKTEDAAIIFDEAKGFEDTAQGRFLIEGSLRQG-RANMTDIYLVTQAFMDY-DKED------KKELLSYKFA 749
gi 123066446 673 LDFi-HS-DRSIFKIVDLDEAWAFLNVAQGETLSNKLVRAG-RAMQAGVYFVTQSAYDV-SKES------LKNNIGLKFA 742
gi 81436856  673 LDFi-HS-NREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAG-RAMNAGVYFVTQNSDDL-LDER------LKNNIGLKFA 742
gi 81436596  673 LDFi-HS-NREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAG-RAMNAGVYFVTQNSDDL-LDER------LKNNIGLKFA 742
gi 81509530  674 LDFi-HT-DRSIFKIVDLDEAWSFLQVAQGKTLSMKLVRAG-RAMNAGVYFVTQNADDL-LDEK------MKNNIGLKFA 743
gi 81345928  688 ELFgmNQ-DEQTVE--FIDEAWIFTTSQQGKKVERQMRRIG-RSYNNAEYFISQSTKDA-LKEE------DSGNFGVAFA 756
gi 81437537  688 SKFg-SR-NRKEETVTFFDEAWIFQSSPEGQKILKSMKRIG-RSFNNFMVLITQSVNDV-LDNG------DGTGFGTVVC 757
gi 81436451  689 SKFg-SR-NPKEETVTFFDESWIFQSSPEGKAILKSMKRIG-RSFNNFLVLITQSTNDL-DDSE------DGTGFGTVIC 758
gi 123525120 653 REVa-FSlPAHIIKGQIFDEVWMLAGISEGARLLDELIRMGaRSYNAIPILATQNASDVaSMQT------IKNNVSYVLC 725
gi 81536497  686 RETa-MA-SKDEFAVAVFDECWYLTSSDEGLELLLELMRDG-RKHNAAAYMGSHDPDDI-GPEGsekgaiLRGLIPHRLM 761
gi 727330608 415 TIF--ST-DKTEDAAIIFDEAKGFEDTAQGRFLIEGSLRQG-RANMTDIYLVTQAFMDY-DKED------KKELLSYKFA 483
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81838800  750 FRPNQKEAQKKVLEFFGMDTNPAN---------I----Q-L------INELKSGTCLFQDHRGRSQPIAIDVLFD-SWLM 808
gi 123066446 743 FRSTDINEIKQTLEFFGIDKDDEN---------N----QkR------LRDLENGQCLLQDLYGRVGVVQIHPVFE-ELLH 802
gi 81436856  743 FRSTDIHEIKKTLEFFGLDQEDES---------N----QkR------LRDLENGQCLMQDLYGRVGVVQVHPVFE-ELFH 802
gi 81436596  743 FRSTDIHEIKKTLEFFGLDQEDES---------N----QkR------LRDLENGQCLMQDLYGRVGVVQVHPVFE-ELFH 802
gi 81509530  744 FRSTDLVEIKKTLTFFGVDPEDEN---------N----QkR------LRELENGQCLISDLYGRVGVMQFHPIFE-ELLQ 803
gi 81345928  757 FD--EPNEREEVLKWMNMEVT-KD---------N----KkM------MESMFQGQCLFKDYYGRTSKISIECLFE-EWQG 813
gi 81437537  758 FDEVDNRE--GILRYLKLPV-NEI---------N----LkW------VSNMIQGQCLMKDMFNQVNRIVIDVIFE-EWLE 814
gi 81436451  759 FD--EVQNREGVLKYLNLPV-NEI---------N----MkW------VSNMVQGQCLMKDMFGQTNRIVVHVIFE-EWLE 815
gi 123525120 726 FRAQDKSEIRSNIELLGADVEEEE---------E----KkGaglanlFRSLESGWCLMKDALGRIGQVYIDPRPE-YLLQ 791
gi 81536497  762 FRQTTRALAVRGLDFLGIDSNDPDlldlvtsglSpidlPeE------ERFARAGECLYRDLAGRVGLMKILIPFDtPVAR 835
gi 727330608 484 FRPNQKEAQKKVLEFFGMDTNPAN---------I----Q-L------INELKSGTCLFQDHRGRSQPIAIDVLFD-SWLM 542

                 ..
gi 81838800  809 AI 810
gi 123066446 803 AF 804
gi 81436856  803 AF 804
gi 81436596  803 AF 804
gi 81509530  804 AF 805
gi 81345928  814 AL 815
gi 81437537  815 LF 816
gi 81436451  816 LF 817
gi 123525120 792 VF 793
gi 81536497  836 AI 837
gi 727330608 543 AV 544
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