4RFS


Conserved Protein Domain Family
ECF_trnsprt

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pfam12822: ECF_trnsprt 
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ECF transporter, substrate-specific component
Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.
Statistics
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PSSM-Id: 338507
View PSSM: pfam12822
Aligned: 58 rows
Threshold Bit Score: 32.6554
Threshold Setting Gi: 501050218
Created: 29-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4RFS_S         8 RL--------------VVDALLMAIVLLqnlvpfLGY---------IPFGPF--------S-MTLIGLTVIvaGSALGPR 55
gi 81533007   32 FVnylknefrfttfdiAISGILFALSLV------SSLivh---htlPPRLNI--------D-TEILFFITF--GIFFGPI 91
gi 501382860  21 AI--------------ILQVLLLASALV------LPAvc-----hhLNLQTK--------V-FLPMHWPVLlaGLVYGWR 66
gi 501424035  11 QL--------------AFAGLFIALGVL------LPIpf-----hiAGIAGS--------I-FLPMHIPVLlaGFYLGGL 56
gi 501338225  27 ML--------------RFIALVTAAAIV------GR----------LIFASI--------PnVQPATALVLlvAACVGPV 68
gi 489765172  16 RM--------------TLIAMLAALGTV------LRv---------FKIIPI--------PnVQPVTDLIMiaTLMLGIG 58
gi 501213873  79 MV--------------AILGVLTGVVAI------LR----------LPAGPA--------D-SPTFFFLIIliGYAYGSR 119
gi 148532122  15 NL--------------TLAAMLIALQVI------LN--------------KLsigdpavlK-FSFGFIATAliGYCLGPW 59
gi 170175292  11 DI--------------AISAVGGALYAL------VGYvsw----lgLTFYGV--------RfWPSVVIPATi-SCLYGAS 57
gi 501050218   9 FL--------------VITAVFIAIAIV------LRPfaitvaaggILTMRI--------S-FDAICYTAP--GLIFGPL 57
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4RFS_S        56 DGLLIGgfwGLITFVRAFT-WPSSPVapliftnplISILPRLLMGLVAG----SLYLWGRHRQWsMr------------- 117
gi 81533007   92 KGVFLS---IITDTFALIL-KGRIAFwm------wEYAISAVFIPIIAS----LLYQIYKNKNL-Klifipitiivvslt 156
gi 501382860  67 SGLTLG---ISAPLASFAL-SGMPPAhi-----lpIMTLELAVYGFAAG--------AFRQQLK-Ln------------- 115
gi 501424035  57 YGLCIG---MITPLISHLV-TGMPPLspip--mlpIMIMELGTYGLLAG----LLY-----NKS-Rg------------- 107
gi 501338225  69 TGAIVG---MLVVVLTSLF-LGSGPFvlf---qiiAYSVISLFCILPGM----------------Qt------------- 112
gi 489765172  59 FGISLA---VMIMVLSNLL-LGFGIWtip---qilAYIVCVVTVAGLAK----------VTPLK-Kh------------- 107
gi 501213873 120 FGFLIG---TLALLVSALLtGGVGPWl-------pFQMFVSGWMGMSAG----FLAPLGRRFRP-Gg------------- 171
gi 148532122  60 IGGWSM---VVSDIISNTIlNSGSLFf-------pGFTLSAFIAGVIAG-----MFLYQQRISW-Qr------------- 110
gi 170175292  58 VGGLSA---AIGIFISDIAtHGNAILsltv--gvtSNFTCFYIIGKLAG---------GNKYSV-Rr------------- 109
gi 501050218  58 YGGIAG---GLIDVFGYMMkPMGGYIp--------LFTITNIIAGILPAvlwrIIRNKSNYKIR-Nyysiffillfligf 125
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4RFS_S       118 -------------------------------Q-AMQVAAGCAALTNTVL------VLGLV---FLFY------------- 143
gi 81533007  157 ggft----------tfafyrpkkgvdiwiwqEvSFISSIVVSTIVALVS------LILIF---LFLFl------------ 205
gi 501382860 116 ------------------------------fIfSLLGAMILGKAVYILT------AYTLA-------------------- 139
gi 501424035 108 ------------------------------aLiSLIGSMIGGRLVAGLM-------VWLL---ITVFg------------ 135
gi 501338225 113 ------------------------------rWiLTAYGLAAGFFYGWIS------NLGFL---IFTDf------------ 141
gi 489765172 108 ------------------------------fTlQLILATFLGFEYGFIV------SLGMS---IYGGw------------ 136
gi 501213873 172 -------------------------------WgEVVLLGGFGYVWGFLF------GALMNlwfWPFAppgelgwlpgsgl 214
gi 148532122 111 ------------------------------iLiYEFFQILLTNVIGTTL------WLYLMslsSSSTg------------ 142
gi 170175292 110 ------------------------------yLvASTLGLTVGHLIIGIG--------------LLLWs------------ 133
gi 501050218 126 infiiikfmsnttlnrlfmflgkksqyfsygFmLIGIIGILILLINLFInknsakFYSFInnyYFKMv------------ 193
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4RFS_S       144 --QTPAVA--Tafga-----------------------------------tgnQTLGYVLMISLFTNGIPELILDVLVAP 184
gi 81533007  206 --YLKTKKdiYfriiiviclivssvvlsrwlmgpyaftnylnrflpskrvrlhKDLYFTWQGPIIIKSLFTIPIYSLILV 283
gi 501382860 140 ---------------------------------------------------------GSASFAFIQTSLPGIILQAVLLP 162
gi 501424035 136 --FQQL------------------------------------------------DYPMAYLSGAVVTGLPGIGLQLFLIP 165
gi 501338225 142 --SR--------------------------------------------------EAFFTLLLTGGFFDLLHGVSNAIFIW 169
gi 489765172 137 ------------------------------------------------------AAFMAYWLSGLLFDFYHAVGNFGCYF 162
gi 501213873 215 aaTIQ-------------------------------------------------QYLRFYIVTSLAWDAVRALGNVILIA 245
gi 148532122 143 ------------------------------------------------------HTFMALLFIRLPKELITWPIETLLVL 168
gi 170175292 134 --QYFPLPfqEsl---------------------------------------tPLSIAAALTISFVTFAWELPFALILVP 172
gi 501050218 194 --IVLGISgiFictintyil-------------------------liftpaliAKGFMLLWIPRIVETLLMTAINSYIVC 246

                 ...
4RFS_S       185 LIA 187
gi 81533007  284 PLI 286
gi 501382860 163 LIA 165
gi 501424035 166 LII 168
gi 501338225 170 LLY 172
gi 489765172 163 ILY 165
gi 501213873 246 LLG 248
gi 148532122 169 VIL 171
gi 170175292 173 PIV 175
gi 501050218 247 IIL 249
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