Conserved Protein Domain Family
LRR_4

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pfam12799: LRR_4 
Leucine Rich repeats (2 copies)
Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Statistics
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Aligned: 267 rows
Threshold Bit Score: 24.1125
Threshold Setting Gi: 0
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WGS:AAPP:GF11041-PA  286 DTLRSLNLM--EN-GIE-EIKLp--dCDplaklNiFMSLEQLNLs--H-NPIW--NEA--DAFNE 337  Drosophila ananassae
Q4QJ80               346 RALKKVDVS--GCaALR-DAAA----LT-----H-LSQLTHVDL-----S-FTavDDV--SSLAY 389  Leishmania major
Q4Q6A2               306 CFLRSVHLS--GC-NVK-DADV----PHl----AqLPCVEEL-Ll--S-RTRI--TNV--QALAA 350  Leishmania major
A0BPX3                67 INLKVVHAS--DC-NLQ-DQNIendfFE-------LDSLKEFNMtknQ-------LSIidR-FTS 112  Paramecium tetraurelia
O81765               300 SNVTVFDASknS--FIG-R--L----PTsf--vG-LTSVEEIDI---SgN--K---LT--GLVPH 342  thale cress
A0EEN6               593 PSLQILQVQ--DN-QLQtCYDTeysiSY-------IPNIQQIDLs--G-N-RI--QSF--GTIIN 639  Paramecium tetraurelia
A0CP28               200 EQLQILSLQn-N--QII-KIFE----PSql--aK-IPKIRQIHVq--G-N------PF--SRFIQ 242  Paramecium tetraurelia
EEN44652             902 KCLRKLSLDh-N--QLL-SIPA----GAl---tT-MRRIDLVDVk--E-N------PF--RCTCA 943  Florida lancelet
21_pfamImport          1 VSIQKLDVS--DN-CFD-SFDAi--lPCv----SqLTRLKCLRLn--G-NPVV--EEP---NFQA 47  
A0BHX4               110 INLQKVYLSy-N--MLI-T--L----PHfl--eS-LTFLEVLDL---SyN------QI--QIYNV 150  Paramecium tetraurelia
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