Conserved Protein Domain Family
zf-rbx1

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pfam12678: zf-rbx1 
RING-H2 zinc finger domain
There are 8 cysteine/ histidine residues which are proposed to be the conserved residues involved in zinc binding. The protein, of which this domain is the conserved region, participates in diverse functions relevant to chromosome metabolism and cell cycle control.
Statistics
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PSSM-Id: 403773
View PSSM: pfam12678
Aligned: 67 rows
Threshold Bit Score: 59.6438
Threshold Setting Gi: 169806172
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4N1R0        28 DNCAICRNHIM--DHCLDCQAKHNKEsqditeqpgCTISWGACGHAFHLHCISTWLKTRRVCPLDN 91  Theileria parva
XP_002115565  38 DTCAICKLLLV--DACMKCQNEIKTEd--------CVVVWGECNHSFHRCCIASWLNKSNRCPLCQ 93  Trichoplax adhaerens
EDW31997      43 DICAICRVQVM--DSCLRCQADNKRDvmg---rqdCVVVWGECNHSFHHCCMSLWVKQNNRCPLCQ 103 Drosophila persimilis
A0CXI2        25 DRCAIDKQSLF--GQCLECEANQVQDe--------CKIVQGLCNHGFHKHCIDRWLKQSNTCPLCN 80  Paramecium tetraurelia
EAX86550      37 DTCAICKLSLV--DKCVQCQANDADDsv------pCPPEFGVCGHGFHKHCIDKWVKTNPTCPLCT 94  Trichomonas vaginalis G3
XP_001830470 319 RTCIICREEMVfqENQPQATPNDREGpn------mTPKKL-PCGHIFHFYCLRSWLERQQSCPTCR 377 Coprinopsis cinerea okayama7#130
EDQ90407      31 DSCAICLDPLT--RTATQDQRP-------------VRLNI--CRHVFHQACIADWQRQSDACPLCR 79  Monosiga brevicollis MX1
XP_001827831 185 IECLICK-----------CEFEKDE----------CMIIL-QCKHKFHDDCIKTWFKFNNACPLCK 228 Enterocytozoon bieneusi H348
Q9SVW0       142 YDSQGCLIPIE--EECIICLEELASSgse----rrIMKLL--CSHSFHKDCILPWLRCKRSCPTCR 199 thale cress
XP_001709381  21 AACAVCKIPCH--ELCPTCASTDST----------CSLVKSKCGHVFHTECIHTWLTSNVICPLCA 74  Giardia lamblia ATCC 50803
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